Results 281 to 290 of about 2,773,088 (322)

Positive feedback loop between MAPK and aquaporin 7 regulates autophagy and apoptosis induced by palmitate in RIN‐m5f cells

FEBS Open Bio, EarlyView.
T2DM is characterized by peripheral blood insulin resistance and progressive pancreatic β‐cell dysfunction. Here, we showed that AQP7, the only aquaglyceroporin protein, regulates autophagy and apoptosis in pancreatic β‐cells. We propose the existence of a positive feedback loop between MAPK signaling and AQP7 that regulates autophagy and apoptosis in ...
Maoqi Wang, Jiang Tan, Xueting He, Yuqin Chen, Guoping Qiu, Mei Yang   +5 more
wiley   +1 more source

Retraction: Puerarin inhibits proliferation and induces apoptosis by upregulation of miR-16 in bladder cancer cell line T24. [PDF]

Oncol Res
Oncology Research Editorial Office.
europepmc   +1 more source

A non‐fluorescent immunohistochemistry method for measuring autophagy flux using MAP1LC3/LC3 and SQSTM1 as core markers

FEBS Open Bio, EarlyView.
We introduce an immunohistochemistry method to measure autophagy flux, highlighting the active degradation and recycling of cellular waste. This cost‐effective approach uses tissue samples to track key markers like LC3 and SQSTM1, revealing how cells maintain health or respond to diseases such as cancer. It bridges the gap between research and clinical
Shahla Shojaei, Amir Barzegar Behrooz, Marco Cordani, Mahmoud Aghaei, Negar Azarpira, Daniel J. Klionsky, Saeid Ghavami   +6 more
wiley   +1 more source

Zein-sodium caseinate-diosmin nanoparticles as a promising anti-cancer agent with targeted efficacy against A2780 cell line. [PDF]

Sci Rep
Faezi M, Motavalizadehkakhky A, Homayouni Tabrizi M, Dolatabadi S, Es-Haghi A.   +4 more
europepmc   +1 more source

Enhancing transporter activity in heterologous expression systems with SAHA: a 2500‐times more potent and odorless alternative to butyrate

FEBS Open Bio, EarlyView.
Heterologous expression of membrane transporters in cultured cells is essential for functional characterization, but is sometimes limited by low activity. Our study compares the HDAC inhibitors butyrate, VPA and SAHA to enhance transport activity. We propose to replace butyrate by SAHA: it is equally effective, devoid of repulsive odor, costs less, and
Svenja Flögel, Maurice Tust, Samira Boussettaoui, Dietmar Fischer, Dirk Gründemann   +4 more
wiley   +1 more source

Establishment of Novel High-Grade Serous Ovarian Carcinoma Cell Line OVAR79. [PDF]

Int J Mol Sci
Shnaider PV, Malyants IK, Ivanova OM, Gordeeva VS, Svirina EA, Zakharzhevskaya NB, Shagaleeva OY, Selezneva OV, Bogomazova AN, Lukina MM, Aleshikova OI, Babaeva NA, Slonov AV, Shender VO.   +13 more
europepmc   +1 more source

Investigating the Cytotoxic Effects of Artemisia absinthium Extract on Oral Carcinoma Cell Line. [PDF]

Biomedicines
Tsamesidis I, Papadimitriou-Tsantarliotou A, Christodoulou A, Amanatidou D, Avgeros C, Stalika E, Bousnaki M, Michailidou G, Beketova A, Eleftheriou P, Bikiaris DN, Vizirianakis IS, Kontonasaki E.   +12 more
europepmc   +1 more source

Sucralose-Enhanced Adipogenesis on Preadipocyte Human Cell Line During Differentiation Process. [PDF]

Int J Mol Sci
Magaña-Gómez JA, González-Ochoa G, Rosas-Rodríguez JA, Stephens-Camacho NA, Flores-Mendoza LK.   +4 more
europepmc   +1 more source

Evaluating feature extraction in ovarian cancer cell line co-cultures using deep neural networks. [PDF]

Commun Biol
Sharma O, Gudoityte G, Minozada R, Kallioniemi OP, Turkki R, Paavolainen L, Seashore-Ludlow B.   +6 more
europepmc   +1 more source

Establishment and Characterization of a Chicken Myoblast Cell Line. [PDF]

Int J Mol Sci
Guo D, Lin S, Wang X, Jiao Z, Li G, An L, Zhang Z, Zhang L.   +7 more
europepmc   +1 more source