Results 21 to 30 of about 18,536,823 (334)

Isolation of a pluripotent cell line from early mouse embryos cultured in medium conditioned by teratocarcinoma stem cells.

Proceedings of the National Academy of Sciences of the United States of America, 1981
This report describes the establishment directly from normal preimplantation mouse embryos of a cell line that forms teratocarcinomas when injected into mice. The pluripotency of these embryonic stem cells was demonstrated conclusively by the observation
G. Martin
semanticscholar   +1 more source

Impact of progesterone on innate immunity and cell death after influenza A virus H1N1 2009 infection of lung and placental cells in vitro

Frontiers in Virology, 2022
The influenza A virus (IAV) 2009 H1N1 pandemic was associated with an increased risk of maternal mortality, preterm birth, and stillbirth. The underlying mechanism for severe maternal lung disease and stillbirth is incompletely understood, but IAV ...
Miranda Li, Miranda Li, Amanda Li, Amanda Li, Hazel Huang, Jeff Munson, Adebimpe Obadan, Deborah H. Fuller, Kristina M. Adams Waldorf, Kristina M. Adams Waldorf   +9 more
doaj   +1 more source

High-throughput identification of genotype-specific cancer vulnerabilities in mixtures of barcoded tumor cell lines. [PDF]

, 2016
Hundreds of genetically characterized cell lines are available for the discovery of genotype-specific cancer vulnerabilities. However, screening large numbers of compounds against large numbers of cell lines is currently impractical, and such experiments
A Basu, Alykhan F Shamji, Andrew Crenshaw, Andrew L Kung, Aristotle M Mannan, Aviad Tsherniak, Bang Wong, Barbara A Weir, Bradley R Taylor, C Ditchfield, Channing Yu, D Peck, E Comer, Griselda Metta Yvone, J Barretina, J Du, JM Korn, Joshua Z Gould, JP Koivunen, JT Lowe, Kenneth N Ross, KT Flaherty, LA Marcaurelle, Levi A Garraway, M Carmena, Melissa A Marton, MI Davis, Michael A Foley, Michelle A Palmer, MJ Garnett, MK Muellner, ML Sos, MW Karaman, NC Turner, OD Abaan, Pablo Tamayo, PD Andrews, SL Schreiber, SM Wilhelm, Stuart L Schreiber, SV Sharma, Todd R Golub, U McDermott, Wendy Winckler, XD Zhang, Yan-Ling Zhang   +45 more
core   +2 more sources

Characteristics of a human cell line transformed by DNA from human adenovirus type 5.

Journal of General Virology, 1977
Human embryonic kidney cells have been transformed by exposing cells to sheared fragments of adenovirus type 5 DNA. The transformed cells (designated 293 cells) exhibited many of the characteristics of transformation including the elaboration of a virus ...
F. Graham, J. Smiley, W. Russell, R. Nairn   +3 more
semanticscholar   +1 more source

Role of crocin in several cancer cell lines: An updated review [PDF]

Iranian Journal of Basic Medical Sciences, 2020
Cancer is a major public health problem worldwide. The most important considerable features of cancer cells are uncontrolled proliferation, up-regulated differentiation, and immortality.
Ali Veisi, Ghaidafeh Akbari, Ali Mard, Gholamreza Badfar, Vahid Zarezade, Mohammad Ali Mirshekar   +5 more
doaj   +1 more source

Multi-scale engineering for neuronal cell growth and differentiation [PDF]

, 2011
In this paper we investigate the role of micropatterning and molecular coating for cell culture and differentiation of neuronal cells (Neuro2a cell line) on a polydimethylsiloxane substrate.
Béduer, Amélie, Flahaut, Emmanuel, Loubinoux, Isabelle, Seichepine, Florent, Vaysse, Laurence, Vieu, Christophe   +5 more
core   +3 more sources

Cell division promotes efficient retrotransposition in a stable L1 reporter cell line [PDF]

, 2013
Background: Long interspersed element type one (L1) actively modifies the human genome by inserting new copies of itself. This process, termed retrotransposition, requires the formation of an L1 ribonucleoprotein (RNP) complex, which must enter the ...
An, Wenfeng, Ivics, Zoltán, Izsvák, Zsuzsanna, Martin, Sandra L., Mátés, Lajos, Xie, Yi   +5 more
core   +2 more sources

Mir-129-2-3p Has Tumor Suppressor Role in Ewing Sarcoma Cell Lines and Cancer Tissue Samples

Brazilian Archives of Biology and Technology, 2021
Deregulation of miRNA expressions was identified as a novel feature of tumor biology in Ewing sarcoma (EWS). The aim was to evaluate the regulatory role of miR-129-2-3p in EWS cell lines and human EWS tissue samples.
Esra Guzel Tanoglu, Yavuz Arıkan, Yavuz Selim Kabukcuoglu, Fevziye Kabukcuoglu, Alpaslan Tanoglu, Sukru Ozturk   +5 more
doaj   +1 more source

Partial Response in an RRx-001-Primed Patient with Refractory Small-Cell Lung Cancer after a Third Introduction of Platinum Doublets. [PDF]

, 2016
Small-cell lung cancer (SCLC), initially exquisitely sensitive to first-line cisplatin/etoposide, invariably relapses and acquires a multidrug chemoresistant phenotype that generally renders retreatment with first-line therapy both futile and ...
Brzezniak, Christina, Cabrales, Pedro, Caroen, Scott, Carter, Corey A, Degesys, Aiste, Oronsky, Bryan, Reid, Tony R, Scicinski, Jan   +7 more
core   +3 more sources

Storage Conditions and Passages Alter IL-6 Secretion in C26 Adenocarcinoma Cell Lines [PDF]

, 2015
The C26 adenocarcinoma tumor line is frequently used to establish peripheral tumors in mice for the study of cancer cachexia and cancer-related fatigue. Recently, we have noticed a progressive decline in the effects of tumor growth on our biological and ...
Devine, Raymond, McCarthy, Donna O., Norden, Diana M., Wold, Loren E.   +3 more
core   +3 more sources