Results 21 to 30 of about 2,769,482 (267)

Genomic and Transcriptomic Characterization of Canine Osteosarcoma Cell Lines: A Valuable Resource in Translational Medicine

open access: yesFrontiers in Veterinary Science, 2021
Osteosarcoma (OSA) represents the most common primary bone tumor in dogs and is characterized by a highly aggressive behavior. Cell lines represent one of the most suitable and reproducible pre-clinical models, and therefore the knowledge of their ...
Cecilia Gola   +8 more
doaj   +1 more source

Establishment and Characterization of Feline Mammary Tumor Patient-Derived Xenograft Model

open access: yesAnimals, 2021
Feline mammary tumor is a relatively commonly diagnosed neoplasm in the cat. Development of new veterinary cancer therapies is limited by the shortage of in vivo models that reproduce tumor microenvironment and metastatic progression. Four feline mammary
Hsiao-Li Chuang   +9 more
doaj   +1 more source

Transplants of Encapsulated Rat Choroid Plexus Cells Exert Neuroprotection in a Rodent Model of Huntington's Disease

open access: yesCell Transplantation, 2007
Choroid plexus (CP) epithelial cells secrete several neurotrophic factors and have been used in transplantation studies designed to impart neuroprotection against central nervous system (CNS) trauma. In the present study, CP was isolated from adult rats,
Cesario V. Borlongan   +4 more
doaj   +1 more source

Generation of an iPSC line from a retinitis pigmentosa patient carrying a homozygous mutation in CERKL and a healthy sibling

open access: yesStem Cell Research, 2019
Dermal fibroblasts from an autosomal recessive retinitis pigmentosa (RP) patient, homozygous for the mutation c.769 C>T, p.Arg257Ter, in CERKL (Ceramide Kinase-Like) gene, and a healthy sibling were derived and reprogrammed by Sendai virus. The generated
Arantxa Bolinches-Amorós   +6 more
doaj   +1 more source

Establishment of A Novel Paclitaxel-Resistant Triple-Negative Breast Cancer Cell Line

open access: yesJournal of Health Science and Medical Research (JHSMR), 2023
Objective: Triple-negative breast cancer (TNBC) is one of the most aggressive subtypes of breast cancer, and is associated with poor prognosis. Paclitaxel, a microtubule-binding agent, and chemotherapeutic agent, has been widely used in the management of
Thanaporn Khunpitak, Pasarat Khongkow
doaj   +1 more source

Mir-129-2-3p Has Tumor Suppressor Role in Ewing Sarcoma Cell Lines and Cancer Tissue Samples

open access: yesBrazilian Archives of Biology and Technology, 2021
Deregulation of miRNA expressions was identified as a novel feature of tumor biology in Ewing sarcoma (EWS). The aim was to evaluate the regulatory role of miR-129-2-3p in EWS cell lines and human EWS tissue samples.
Esra Guzel Tanoglu   +5 more
doaj   +1 more source

Do-it-yourself instrument integration into an existing mammalian cell line development automation platform

open access: yesSLAS Technology
Laboratory automation in the biopharmaceutical industry as a rule requires contracted service from highly professional automation solution provider, at times involving the purchase and development of specialized or customized hardware and software, which
Jie Ding, Kee Wee Tan, Xiaoyue Chen
doaj   +1 more source

Impact of progesterone on innate immunity and cell death after influenza A virus H1N1 2009 infection of lung and placental cells in vitro

open access: yesFrontiers in Virology, 2022
The influenza A virus (IAV) 2009 H1N1 pandemic was associated with an increased risk of maternal mortality, preterm birth, and stillbirth. The underlying mechanism for severe maternal lung disease and stillbirth is incompletely understood, but IAV ...
Miranda Li   +9 more
doaj   +1 more source

Fibroblasts cell lines misclassified as cancer cell lines [PDF]

open access: yes, 2017
Large collections of immortalized cancer cell lines have been widely used as model systems for cancer research and drug discovery. Some of these models however display more fibroblast-like than cancer-like characteristics based on their genetic and genomic characterization. The correct annotation of these cell lines remains a challenge. Here, we report
de Weck, Antoine   +2 more
openaire   +1 more source

Mouse cell line authentication [PDF]

open access: yesCytotechnology, 2013
The scientific community has responded to the misidentification of human cell lines with validated methods to authenticate these cells; however, few assays are available for nonhuman cell line identification. We have developed a multiplex polymerase chain reaction assay that targets nine tetranucleotide short tandem repeat (STR) markers in the mouse ...
Almeida, Jamie L.   +2 more
openaire   +2 more sources

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