Macrocyclic Peptides Closed by a Thioether-Bipyridyl Unit That Grants Cell Membrane Permeability. [PDF]
ACS Bio Med Chem Au, 2023 Membrane permeability is an important factor that determines the virtue of peptides targeting intracellular molecules. By introducing a membrane penetration motif, some peptides exhibit better membrane permeabilities.
Chen H, Katoh T, Suga H.
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Cold Atmospheric Plasma Treatment of Chondrosarcoma Cells Affects Proliferation and Cell Membrane Permeability. [PDF]
Int J Mol Sci, 2020 Chondrosarcoma is the second most common malign bone tumor in adults. Surgical resection of the tumor is recommended because of its resistance to clinical treatment such as chemotherapy and radiation therapy.
Haralambiev L +7 more
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The Antifungal Peptide MCh-AMP1 Derived From Matricaria chamomilla Inhibits Candida albicans Growth via Inducing ROS Generation and Altering Fungal Cell Membrane Permeability. [PDF]
Front Microbiol, 2019 The rise of antifungal drug resistance in Candida species responsible for life threatening candidiasis is considered as an increasing challenge for the public health. MCh-AMP1 has previously been reported as a natural peptide from Matricaria chamomilla L.
Seyedjavadi SS +10 more
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Mode of action of the antimicrobial peptide Mel4 is independent of Staphylococcus aureus cell membrane permeability. [PDF]
PLoS One, 2019 Mel4 is a novel cationic peptide with potent activity against Gram-positive bacteria. The current study examined the anti-staphylococcal mechanism of action of Mel4 and its precursor peptide melimine.
Yasir M, Dutta D, Willcox MDP.
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Characterization of Cell Membrane Permeability In Vitro Part II: Computational Model of Electroporation-Mediated Membrane Transport. [PDF]
Technol Cancer Res Treat, 2018 Electroporation is the process by which applied electric fields generate nanoscale defects in biological membranes to more efficiently deliver drugs and other small molecules into the cells.
Sweeney DC, Douglas TA, Davalos RV.
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Tracer Determinations of Human Red Cell Membrane Permeability to Small Nonelectrolytes [PDF]
The Journal of General Physiology, 1971 A flow system has been used to determine the permeability of human red cell membranes to four small nonelectrolytes labeled with 14C. The permeability coefficients, ω, in units of mol dyne-1 sec-1 x 1015, are: ethylene glycol, 6; urea, 13; formamide, 22;
David Savitz, A. K. Solomon
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Autophagic cell death is dependent on lysosomal membrane permeability through Bax and Bak
eLife, 2017 Cells deficient in the pro-death Bcl-2 family members Bax and Bak are known to be resistant to apoptotic cell death, and previous we have shown that these two effectors are also needed for mitochondrial-dependent cellular necrosis (Karch et al., 2013 ...
Jason Karch +6 more
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Red Cell Membrane Permeability Deduced from Bulk Diffusion Coefficients [PDF]
The Journal of General Physiology, 1974 The permeability coefficients of dog red cell membrane to tritiated water and to a series of[14C]amides have been deduced from bulk diffusion measurements through a "tissue" composed of packed red cells. Red cells were packed by centrifugation inside polyethylene tubing.
W R, Redwood, E, Rall, W, Perl
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Synthesis of practical red fluorescent probe for cytoplasmic calcium ions with greatly improved cell-membrane permeability [PDF]
Data in Brief, 2017 In this data article, we described the detailed synthetic procedure and the experimental data for the synthesis of a red-fluorescent probe for calcium ions (Ca2+) with improved water solubility.
Kazuhisa Hirabayashi +10 more
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The Nanopore Connection to Cell Membrane Unitary Permeability [PDF]
Traffic, 2005 Artificial nanopores have recently emerged as versatile tools for analyzing and sorting single molecules at high speed. However, the biological cell has already developed a large set of sophisticated protein nanopores that are able to selectively translocate all types of molecules through membranes.
Reiner Peters
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