Results 41 to 50 of about 446,721 (287)
A Bioinspired Cell Membrane Disruptor Opens Pyroptosis-deficient Cells Membrane and Ignites Powerful Antitumour Immune Function [PDF]
, 2023 Gasdermin protein, a membrane disruptor, can mediate immunogenic pyroptosis and elicit anti-tumour immune function. However, cancer cells downregulate gasdermin and develop membrane repair mechanisms to resist pyroptosis.
Qinyang, Wang +7 more
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Toxins, 2018 The largest superfamily of bacterial virulence factors is pore-forming toxins (PFTs). PFTs are secreted by both pathogenic and non-pathogenic bacteria. PFTs sometimes kill or induce pro-pathogen signaling in mammalian cells, all primarily through plasma ...
Sucharit Ray +2 more
doaj +1 more source
Plasma membrane integrity: implications for health and disease
BMC Biology, 2021 Plasma membrane integrity is essential for cellular homeostasis. In vivo, cells experience plasma membrane damage from a multitude of stressors in the extra- and intra-cellular environment.
Dustin A. Ammendolia +2 more
doaj +1 more source
Frontiers in Microbiology, 2021 Staphylococcus aureus (S. aureus) is well known to express a plethora of toxins of which the pore-forming hemolysin A (α-toxin) is the best-studied cytolysin.
David Krones +8 more
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Annexins: players of single cell wound healing and regeneration
Communicative & Integrative Biology, 2019 Cell life is defined by a thin 4 nm plasma membrane, which separates the interior of a cell from its environment. Thus, disruption of the plasma membrane poses a critical risk to cells, which requires immediate repair to avoid uncontrolled osmotic lysis ...
Swantje Christin Häger +1 more
doaj +1 more source
Scientific Reports, 2021 Plasma membrane repair is essential for eukaryotic cell life and is triggered by the influx of calcium through membrane wounds. Repair consists of sequential steps, with closure of the membrane hole being the key event that allows the cell to recover ...
Martin Berg Klenow +3 more
doaj +1 more source
Phosphatidylethanolamine positively regulates autophagy and longevity [PDF]
, 2015 This work was supported by the Austrian Science Fund FWF (grants LIPOTOX, I1000-B20, P23490-B12, and P24381-B20) to FM. The authors acknowledge support from NAWI Graz.
Pietrocola, F. +30 more
core +1 more source
A Combination Hyaluronic Acid-Collagen Fiber Scaffold for Tympanic Membrane Repair [PDF]
, 2022 Tympanic membrane perforation (TMP) can cause recurrent ear infections and chronic TMP. Treatments designed to repair TMP involve reconstruction of the TM with autologous tissue grafts. These autologous grafts have limitations.
Cervantes Gonzalez, Mireya Yareth
core
High-Throughput Microplate-Based Assay to Monitor Plasma Membrane Wounding and Repair
Frontiers in Cellular and Infection Microbiology, 2017 The plasma membrane of mammalian cells is susceptible to disruption by mechanical and biochemical damages that frequently occur within tissues. Therefore, efficient and rapid repair of the plasma membrane is essential for maintaining cellular homeostasis
Sarika Pathak-Sharma +6 more
doaj +1 more source
Long-Term Potentiation of Exocytosis and Cell Membrane Repair in Fibroblasts [PDF]
Molecular Biology of the Cell, 2003 We previously found that a microdisruption of the plasma membrane evokes Ca2+-regulated exocytosis near the wound site, which is essential for membrane resealing. We demonstrate herein that repeated membrane disruption reveals long-term potentiation of Ca2+-regulated exocytosis in 3T3 fibroblasts, which is closely correlated with faster membrane ...
Tatsuru, Togo +2 more
openaire +2 more sources