Results 21 to 30 of about 446,721 (287)
Plasma membrane integrity in health and disease: significance and therapeutic potential
Cell Discovery, 2021 Maintenance of plasma membrane integrity is essential for normal cell viability and function. Thus, robust membrane repair mechanisms have evolved to counteract the eminent threat of a torn plasma membrane.
Catarina Dias, Jesper Nylandsted
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Advances in cell membrane-encapsulated biomaterials for tissue repair and regeneration [PDF]
, 2022 The evolution of tissue engineering and regenerative medicine have enabled better treatment outcomes for tissue reconstruction, although several shortcomings remain.
Xiao, Yin +3 more
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MG53, A Tissue Repair Protein with Broad Applications in Regenerative Medicine
Cells, 2021 Under natural conditions, injured cells can be repaired rapidly through inherent biological processes. However, in the case of diabetes, cardiovascular disease, muscular dystrophy, and other degenerative conditions, the natural repair process is impaired.
Zhongguang Li +6 more
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A Decrease in Membrane Tension Precedes Successful Cell-Membrane Repair [PDF]
Molecular Biology of the Cell, 2000 We hypothesized that the requirement for Ca2+-dependent exocytosis in cell-membrane repair is to provide an adequate lowering of membrane tension to permit membrane resealing. We used laser tweezers to form membrane tethers and measured the force of those tethers to estimate the membrane tension of Swiss 3T3 fibroblasts after membrane disruption and ...
T, Togo, T B, Krasieva, R A, Steinhardt
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Toxins, 2021 Pore-forming toxins (PFTs) form multimeric trans-membrane pores in cell membranes that differ in pore channel diameter (PCD). Cellular resistance to large PFTs (>20 nm PCD) was shown to rely on Ca2+ influx activated membrane repair mechanisms. Small PFTs
Yu Larpin +4 more
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Plasma Membrane Repair Is Regulated Extracellularly by Proteases Released from Lysosomes. [PDF]
PLoS ONE, 2016 Eukaryotic cells rapidly repair wounds on their plasma membrane. Resealing is Ca(2+)-dependent, and involves exocytosis of lysosomes followed by massive endocytosis.
Thiago Castro-Gomes +3 more
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Clinical and Translational Discovery, 2023 Background Annexin A2 contributes to several key cellular functions and processes, including membrane repair. Effective repair prevents cell death and degeneration, especially in skeletal or cardiac muscle, epithelia, and endothelial cells.
Victor G. Kayejo +3 more
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Tracking cell layer contribution during repair of the tympanic membrane
Disease Models & Mechanisms, 2023 ABSTRACT The tympanic membrane (i.e. eardrum) sits at the interface between the middle and external ear. The tympanic membrane is composed of three layers: an outer ectoderm-derived layer, a middle neural crest-derived fibroblast layer with contribution from the mesoderm-derived vasculature, and an inner endoderm-derived mucosal layer.
Olivia M. Dinwoodie +2 more
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Enhancing membrane repair increases regeneration in a sciatic injury model.
PLoS ONE, 2020 Various injuries to the neural tissues can cause irreversible damage to multiple functions of the nervous system ranging from motor control to cognitive function.
Brian J Paleo +7 more
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Materials Today Bio, 2023 The presence of periosteum can greatly affect the repair of a bone fracture. An artificial periosteum imitates the biological function of natural periosteum, which is capable of protecting and maintaining bone tissue structure and promoting bone repair ...
Wentao Zhang +8 more
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