Results 171 to 180 of about 551,941 (324)

Large‐scale bidirectional arrayed genetic screens identify OXR1 and EMC4 as modifiers of αSynuclein aggregation

FEBS Open Bio, EarlyView.
Activation of the mitochondrial protein OXR1 increases pSyn129 αSynuclein aggregation by lowering ATP levels and altering mitochondrial membrane potential, particularly in response to MSA‐derived fibrils. In contrast, ablation of the ER protein EMC4 enhances autophagic flux and lysosomal clearance, broadly reducing α‐synuclein aggregates.
Sandesh Neupane, Lea Nikolić, Lorenzo Maraio, Thomas Goiran, Nathan Karpilovsky, Stefano Sellitto, Vangelis Bouris, Jiang‐An Yin, Ronald Melki, Edward A Fon, Adriano Aguzzi, Elena De Cecco   +11 more
wiley   +1 more source

3P197 Effects of cellular aggregation on anoikis of MDCK cells(Cell biological problems-adhesion, motility, cytoskeleton, signaling, and membrane,Poster Presentations)

, 2007
Yumiko Emoto
openalex   +2 more sources

Supplementary Figure 1 from Exosomes from Nischarin-Expressing Cells Reduce Breast Cancer Cell Motility and Tumor Growth

, 2023
Mazvita Maziveyi, Shengli Dong, Somesh Baranwal, Ali Mehrnezhad, Rajamani Rathinam, Thomas M. Huckaba, Donald E. Mercante, Kidong Park, Suresh K. Alahari   +8 more
openalex   +1 more source

Development of the nonreceptor tyrosine kinase FER-targeting PROTACs as a potential strategy for antagonizing ovarian cancer cell motility and invasiveness [PDF]

, 2023
Yanchun Zhang, Xuexue Xiong, Renhong Sun, Xiaotong Zhu, Chen Wang, Biao Jiang, Xiaobao Yang, Dake Li, Gaofeng Fan   +8 more
openalex   +1 more source

The skills required for transition to university and study in biological sciences: A student perspective

FEBS Open Bio, EarlyView.
Bioscience students were asked for their opinions on the value and teaching of skills. 204 responded that teamwork, time management and study skills are necessary to reach University, that scientific writing, research, laboratory and presentation skills are taught effectively during their studies, while other skills are gained inherently through study ...
Janella Borrell, Susan Crennell
wiley   +1 more source

Optogenetic control of PLC-γ1 activity directs cell motility. [PDF]

J Cell Biol
Appalabhotla R, Siesser PF, Truscott H, Hajicek N, Sondek J, Bear JE, Haugh JM.   +6 more
europepmc   +1 more source

Reviewer #1 (Public review): Synaptic cell adhesion molecule Cdh6 identifies a class of sensory neurons with novel functions in colonic motility

openalex   +1 more source

Suppression of lung adenocarcinoma migration through organelle alkalization by human lactoferrin – albumin fusion

FEBS Open Bio, EarlyView.
This paper reveals how human lactoferrin–albumin fusion (hLF‐HSA) potently suppresses lung adenocarcinoma cell migration. hLF‐HSA upregulates NHE7, leading to Golgi alkalization, disruption of the Golgi secretome, downregulation of MMP1, and reversal of EMT. These findings suggest a novel Golgi‐targeting strategy to suppress cancer cell migration.
Hana Nopia, Masahiro Kimura, Daisuke Kurimoto, Atsushi Sato   +3 more
wiley   +1 more source

2P194 Reconstitution of stator proteins of the bacterial flagellar motor in membrane using cell-free protein synthesis system(Cell biological problems-adhesion, motility, cytoskeleton, signaling,and membrane,Oral Presentations)

, 2007
Hiroyuki Terashima, Seiji Kojima, Michio Homma   +2 more
openalex   +2 more sources

Iroquois homeobox 2 suppresses cellular motility and chemokine expression in breast cancer cells [PDF]

, 2015
Stefan Werner, Hauke Stamm, Mutiha Pandjaitan, Dirk Kemming, Benedikt Brors, Klaus Pantel, Harriet Wikman   +6 more
openalex   +1 more source