Results 151 to 160 of about 1,616,474 (251)

A chemorepellent inhibits local Ras activation to inhibit pseudopod formation to bias cell movement away from the chemorepellent. [PDF]

Mol Biol Cell, 2022
Kirolos SA, Gomer RH.
europepmc   +1 more source

Matrix metalloproteinase‐9 regulates cell adhesion and membrane protrusive activity of ovarian cancer cells

FEBS Open Bio, EarlyView.
Matrix metalloproteinase‐9 (MMP9) drives ovarian cancer progression. Using MMP9‐null cells (M9‐KO) created from ovarian cancer cells, we found MMP9 loss did not block Epidermal Growth Factor (EGF)‐driven E‐cadherin dissolution or EMT but delayed and reduced EGF‐driven membrane protrusions. Transient MMP9 re‐expression drove membrane protrusion.
Claire Strauel, Sam Bennett, Natalie Ehlinger, Nelson Cook, Katelyn Marvin, Caleb L. Lines, Sam Reyes, Brooke Kirby, Shawn M. Ellerbroek   +8 more
wiley   +1 more source

Editorial: Ethological dynamics in diorama environments

Frontiers in Cell and Developmental Biology
Toshiyuki Nakagaki, Audrey Dussutour, Audrey Dussutour, Laurence Wilson, Takuji Ishikawa   +4 more
doaj   +1 more source

Cell-derived Matrix Assays to Assess Extracellular Matrix Architecture and Track Cell Movement.

Bio Protoc, 2022
Murphy KJ, Reed DA, Chambers CR, Zhu J, Magenau A, Pereira BA, Timpson P, Herrmann D.   +7 more
europepmc   +1 more source

Decreased cold‐sensing function of the transient receptor potential channel TRPM8 from tailed amphibians

FEBS Open Bio, EarlyView.
Despite frogs avoiding low temperatures, examination of four salamander species revealed that none avoided cold and all possessed cold tolerance. Functional analysis of TRPM8, a cold sensor, showed that all salamander TRPM8s had lost their cold sensitivity.
Tadahiro Sawao, Daiki Kobayashi, Shogo Hori, Osamu Saitoh   +3 more
wiley   +1 more source

Forty-five years of cGMP research in Dictyostelium: understanding the regulation and function of the cGMP pathway for cell movement and chemotaxis. [PDF]

Mol Biol Cell, 2021
van Haastert PJM, Keizer-Gunnink I, Pots H, Ortiz-Mateos C, Veltman D, van Egmond W, Kortholt A.   +6 more
europepmc   +1 more source

Large‐scale bidirectional arrayed genetic screens identify OXR1 and EMC4 as modifiers of αSynuclein aggregation

FEBS Open Bio, EarlyView.
Activation of the mitochondrial protein OXR1 increases pSyn129 αSynuclein aggregation by lowering ATP levels and altering mitochondrial membrane potential, particularly in response to MSA‐derived fibrils. In contrast, ablation of the ER protein EMC4 enhances autophagic flux and lysosomal clearance, broadly reducing α‐synuclein aggregates.
Sandesh Neupane, Lea Nikolić, Lorenzo Maraio, Thomas Goiran, Nathan Karpilovsky, Stefano Sellitto, Vangelis Bouris, Jiang‐An Yin, Ronald Melki, Edward A Fon, Adriano Aguzzi, Elena De Cecco   +11 more
wiley   +1 more source

Tracking Cell Movement in Two-Dimensional, Fragmented Microcosms Reveals Dispersal Syndromes and Strategies in <i>Tetrahymena thermophila</i>. [PDF]

Ecol Evol
Manzi F, Brans V, Dacek M, Jacob S, Schtickzelle N.   +4 more
europepmc   +1 more source

The skills required for transition to university and study in biological sciences: A student perspective

FEBS Open Bio, EarlyView.
Bioscience students were asked for their opinions on the value and teaching of skills. 204 responded that teamwork, time management and study skills are necessary to reach University, that scientific writing, research, laboratory and presentation skills are taught effectively during their studies, while other skills are gained inherently through study ...
Janella Borrell, Susan Crennell
wiley   +1 more source

Functionality of potato virus Y coat protein in cell-to-cell movement dynamics is defined by its N-terminal region. [PDF]

J Virol
Vozelj A, Mahkovec Povalej T, Stare K, Tušek Žnidarič M, Bačnik K, Levak V, Gutiérrez-Aguirre I, Podobnik M, Gruden K, Coll A, Lukan T.   +10 more
europepmc   +1 more source