Results 161 to 170 of about 1,616,474 (251)

Suppression of lung adenocarcinoma migration through organelle alkalization by human lactoferrin – albumin fusion

FEBS Open Bio, EarlyView.
This paper reveals how human lactoferrin–albumin fusion (hLF‐HSA) potently suppresses lung adenocarcinoma cell migration. hLF‐HSA upregulates NHE7, leading to Golgi alkalization, disruption of the Golgi secretome, downregulation of MMP1, and reversal of EMT. These findings suggest a novel Golgi‐targeting strategy to suppress cancer cell migration.
Hana Nopia, Masahiro Kimura, Daisuke Kurimoto, Atsushi Sato   +3 more
wiley   +1 more source

Five questions on the cell-to-cell movement of Orthotospoviruses. [PDF]

BBA Adv
Singh P, Raj R, Savithri HS.
europepmc   +1 more source

Why human connection is the true metric of research success

FEBS Open Bio, EarlyView.
Human‐centred mentorship can be shaped by mentor attributes, actions, intrinsic drive and career ambition. Drawing on reflections across Singapore and France, as well as workshop insights from FEBS‐IUBMB ENABLE 2024, this article shows that human‐centred mentorship creates the conditions for sustainable growth, well‐being and retention in research ...
Timothy Lin Yun Tan, Mattias Wei Ren Kon, Xavier Coumoul, Fun Man Fung   +3 more
wiley   +1 more source

Ethanol downregulates gastrula gene expression and cell movement, causing symptoms of foetal alcohol spectrum disorders. [PDF]

Biol Open
Alsakran AA, Gibson B, Wong HY, Heaton C, Boreham R, Minhas R, Ball J, Kudoh T.   +7 more
europepmc   +1 more source

Exploring the Multifunctional Roles of Odontoglossum Ringspot Virus P126 in Facilitating Cymbidium Mosaic Virus Cell-to-Cell Movement during Mixed Infection. [PDF]

Viruses, 2021
Lee SC, Pai H, Huang YW, He MH, Song YL, Kuo SY, Chang WC, Hsu YH, Lin NS.   +8 more
europepmc   +1 more source

Blood‐based proteomic profiling reveals context‐dependent changes in BCL2‐associated signaling during taxane therapy in breast cancer patients

FEBS Open Bio, EarlyView.
Chemotherapy side effects significantly impact cancer survivors' quality of life. Using protein levels in blood samples from breast cancer patients before and after 12 weeks of taxane treatment, we detected treatment‐dependent changes in calcium signaling and aging pathways associated with cancer recurrence.
Saira Munshani, Eiman Y. Ibrahim, Rozalyn L. Rodwin, Leah M. Ferrucci, Kim Blenman, Maryam Lustberg, Barbara E. Ehrlich   +6 more
wiley   +1 more source

Approximate Bayesian inference in a model for self-generated gradient collective cell movement. [PDF]

Comput Stat
Devlin J, Borowska A, Husmeier D, Mackenzie J.   +3 more
europepmc   +1 more source

The conserved aromatic residue W¹²² is a determinant of potyviral coat protein stability, replication, and cell-to-cell movement in plants. [PDF]

Mol Plant Pathol, 2021
Yan ZY, Cheng DJ, Liu LZ, Geng C, Tian YP, Li XD, Valkonen JPT.   +6 more
europepmc   +1 more source

Long‐term hippocampal alterations and cognitive impairment in a murine model of surgical sepsis

FEBS Open Bio, EarlyView.
Using a mouse model of surgical sepsis, we tested long‐term memory and analyzed the transcriptome of single cells isolated from the hippocampus. Survivor mice showed worse memory, loss of certain brain cell subpopulations, and abnormal immune cell activity—suggesting that post‐sepsis brain alterations may be linked to cognitive deficits.
Dong Seong Cho, Rebecca Schmitt, Aneesha Dasgupta, Alexandra Ducharme, Jason Doles   +4 more
wiley   +1 more source

HSP90 interacts with VP37 to facilitate the cell-to-cell movement of broad bean wilt virus 2. [PDF]

mBio
Kim M-H, Jang S-Y, Choi J-S, Kim S, Lee Y, Park S, Kwon S-J, Seo J-K.   +7 more
europepmc   +1 more source