Nuclear Phosphoinositides—Versatile Regulators of Genome Functions
The many functions of phosphoinositides in cytosolic signaling were extensively studied; however, their activities in the cell nucleus are much less clear.
Enrique Castano +7 more
doaj +1 more source
Immunocytochemical localization of chromatin regions UV-microirradiated in S phase or anaphase : Evidence for a territorial organization of chromosomes during cell cycle of cultured Chinese hamster cells [PDF]
Chinese hamster cells (M3-1 line) in S phase were laser-UV-microirradiated (λ, 257 nm) at a small site of the nucleus. Cells were fixed either immediately thereafter or in subsequent stages of the cell cycle, including prophase and metaphase.
Avivi +33 more
core +1 more source
MONONUCLEOTIDES OF THE CELL NUCLEUS [PDF]
1. It has been demonstrated by ion exchange chromatography that the cell nucleus contains mononucleotides of adenine, guanine, cytosine, uracil, together with diphosphopyridine nucleotide, and several uridine diphosphate derivatives; the adenine nucleotides predominating in amount.
V G, ALLFREY, A E, MIRSKY, S, OSAWA
openaire +2 more sources
The cell nucleus is the information centre of the cell. It is responsible for copying highly selected regions of the genome into ribonucleic acid (RNA) and for supplying precisely regulated amounts of specific RNA molecules to the cytoplasm, where they are translated into proteins.
openaire +2 more sources
Lipid Microdomains in Cell Nucleus [PDF]
It is known that nuclear lipids play a role in proliferation, differentiation, and apoptotic process. Cellular nuclei contain high levels of phosphatidylcholine and sphingomyelin, which are partially linked with cholesterol and proteins to form lipid–protein complexes.
Giacomo, Cascianelli +6 more
openaire +2 more sources
The connections of the inferior colliculus and the organization of the brainstem auditory system in the greater horseshoe bat (Rhinolophus ferrumequinum) [PDF]
The connections of the inferior colliculus, the mammalian midbrain auditory center, were determined in the greater horseshoe bat (Rhinolophus ferrumequinum), using the horseradish peroxidase method.
Adams +70 more
core +1 more source
The Role of Nuclear Insulin and IGF1 Receptors in Metabolism and Cancer
Insulin (InsR) and insulin-like growth factor-1 (IGF1R) receptors mediate the metabolic and growth-promoting actions of insulin and IGF1/IGF2, respectively.
Haim Werner, Rive Sarfstein, Zvi Laron
doaj +1 more source
Preganglionic innervation of the pancreas islet cells in the rat [PDF]
The position and number of preganglionic somata innervating the insulin-secreting β-cells of the endocrine pancreas were investigated in Wistar rats.
Horst, G.J. ter, +4 more
core +2 more sources
Modular Nanotransporters for Nuclear-Targeted Delivery of Auger Electron Emitters
This review describes artificial modular nanotransporters (MNTs) delivering their cargos into target cells and then into the nuclei – the most vulnerable cell compartment for most anticancer agents and especially for radionuclides emitting short-range ...
Alexander S. Sobolev +1 more
doaj +1 more source
Rabl's model of the interphase chromosome arrangement tested in Chinise hamster cells by premature chromosome condensation and laser-UV-microbeam experiments [PDF]
In 1885 Carl Rabl published his theory on the internal structure of the interphase nucleus. We have tested two predictions of this theory in fibroblasts grown in vitro from a female Chinese hamster, namely (1) the Rabl-orientation of interphase ...
C Cremer +34 more
core +1 more source

