Results 41 to 50 of about 7,362,319 (231)
Mathematics, 2022 We consider the usual random allocation model of distinguishable particles into distinct cells in the case when there are an even number of particles in each cell. For inhomogeneous allocations, we study the numbers of particles in the first K cells. We prove that, under some conditions, this K-dimensional random vector with centralised and normalised ...
Alexey Nikolaevich Chuprunov +1 more
openaire +2 more sources
Unraveling Mycobacterium tuberculosis acid resistance and pH homeostasis mechanisms
FEBS Letters, EarlyView.Mycobacterium tuberculosis exhibits a remarkable resilience to acid stress. In this Review, we discuss some of the molecular mechanisms and metabolic pathways used by the tubercle bacilli to adapt and resist host‐mediated acid stress. Mycobacterium tuberculosis (Mtb) is a successful pathogen that has developed a variety of strategies to survive and ...
Janïs Laudouze +3 more
wiley +1 more source
Moment-based analysis of biochemical networks in a heterogeneous population of communicating cells
, 2019 Cells can utilize chemical communication to exchange information and coordinate their behavior in the presence of noise. Communication can reduce noise to shape a collective response, or amplify noise to generate distinct phenotypic subpopulations.
Gonzales, David T. +2 more
core +1 more source
FEBS Letters, EarlyView.Venom peptides have shown promise in treating pain. Our study uses computer screening to identify a peptide that targets a sodium channel (NaV1.7) linked to chronic pain. We produced the peptide in the laboratory and refined its design, advancing the search for innovative pain therapies.
Gagan Sharma +8 more
wiley +1 more source
Multi-Cell Random Beamforming: Achievable Rate and Degrees of Freedom Region
, 2013 Random beamforming (RBF) is a practically favourable transmission scheme for multiuser multi-antenna downlink systems since it requires only partial channel state information (CSI) at the transmitter.
Hui, Hon Tat +2 more
core +1 more source
The power of microRNA regulation—insights into immunity and metabolism
FEBS Letters, EarlyView.MicroRNAs are emerging as crucial regulators at the intersection of metabolism and immunity. This review examines how miRNAs coordinate glucose and lipid metabolism while simultaneously modulating T‐cell development and immune responses. Moreover, it highlights how cutting‐edge artificial intelligence applications can identify miRNA biomarkers ...
Stefania Oliveto +2 more
wiley +1 more source
STR profiling and Copy Number Variation analysis on single, preserved cells using current Whole Genome Amplification methods [PDF]
, 2017 The growing interest in liquid biopsies for cancer research and cell-based non-invasive prenatal testing (NIPT) invigorates the need for improved single cell analysis.
Cornelis, Senne +5 more
core +2 more sources
On the Number of ON Cells in Cellular Automata [PDF]
, 2018 If a cellular automaton (CA) is started with a single ON cell, how many cells will be ON after n generations? For certain "odd-rule" CAs, including Rule 150, Rule 614, and Fredkin's Replicator, the answer can be found by using the combination of a new transformation of sequences, the run length transform, and some delicate scissor cuts.
openaire +2 more sources
Regulation of glomerular cell number by apoptosis [PDF]
Kidney International, 1999 While commonly viewed as leading to glomerular scarring and end-stage renal failure, glomerular cell proliferation may be a beneficial response that promotes the injured glomerulus to return to its proper function. This brief review looks at the potentially counterbalancing influences that cause glomerular cells to survive, undergo mitosis ...
openaire +3 more sources
Identification of novel small molecule inhibitors of ETS transcription factors
FEBS Letters, EarlyView.ETS transcription factors play an essential role in tumourigenesis and are indispensable for sprouting angiogenesis, a hallmark of cancer, which fuels tumour expansion and dissemination. Thus, targeting ETS transcription factor function could represent an effective, multifaceted strategy to block tumour growth. The evolutionarily conserved E‐Twenty‐Six
Shaima Abdalla +9 more
wiley +1 more source