Results 161 to 170 of about 61,199 (301)

Plant‐Produced Viral Nanoparticles Decorated with Nanobodies Against HER2 Improve Retention and Recruitment of Immune Cells in Solid Tumors

Advanced Healthcare Materials, EarlyView.
Potato virus X is a filamentous RNA plant virus that can be engineered into a molecular tool for cancer therapy. We produced genetically‐encoded virus‐derived nanoparticles decorated with nanobodies targeting cancer cell receptors, epidermal growth factor receptor (EGFR) and human epidermal growth factor 2 (HER2).
Enrique Lozano‐Sanchez, Miguel A. Moreno‐Gonzalez, Fernando Merwaiss, Nicole F. Steinmetz, José‐Antonio Daròs   +4 more
wiley   +1 more source

Cell-Penetrating Peptides and Supercharged Proteins: A Comprehensive Protocol from Isolation to Cellular Uptake. [PDF]

Mol Pharm
Beribisky AV, Sarne V, Huber A, Hengstschläger M, Laccone F, Steinkellner H.   +5 more
europepmc   +1 more source

Inhibition of regulated cell death by cell-penetrating peptides [PDF]

, 2016

core   +1 more source

A Physiological Microfluidic Blood–Brain‐Barrier Model for In Vitro Study of Nanoparticle Trafficking and Accumulation

Advanced Healthcare Materials, EarlyView.
A human microfluidic blood‐brain barrier (mBBB) model enables spatially resolved comparison of nanoparticle trafficking. Extracellular vesicles (EVs), liposomes, and nanoplastics exhibit distinct transport and disruption behaviors, revealing that membrane composition and uptake pathways govern BBB interaction.
Bryan B. Nguyen, Neona M. Lowe, Sophia Kellogg, Kuan‐Wei Huang, Hannah O'Toole, Elizabeth J. Hale, Venktesh S. Shirure, Bhupinder S. Shergill, Steven C. George, Randy P. Carney   +9 more
wiley   +1 more source

Loading of therapeutic cell penetrating peptides into extracellular vesicles for pulmonary fibrosis. [PDF]

J Control Release
Lowe NM, Nguyen BB, Mizenko RR, Trushchankova A, Hadley DJ, Panitch A, Carney RP.   +6 more
europepmc   +1 more source

Polyarginine Cell-Penetrating Peptides Bind and Inhibit SERCA2. [PDF]

Cells, 2023
Lunde PK, Manfra O, Støle TP, Lunde M, Martinsen M, Carlson CR, Louch WE.   +6 more
europepmc   +1 more source

3D Soft Hydrogels Induce Human Mesenchymal Stem Cells “Deep” Quiescence

Advanced Healthcare Materials, EarlyView.
Three‐dimensional soft hydrogels mimicking the bone marrow niche induce deep quiescence in human mesenchymal stem cells. Unlike 2D culture, 3D matrices halt proliferation, regulate cell‐cycle and quiescence markers, and downregulate mTORC1 signaling, preserving stem cell phenotype and therapeutic potential ex vivo.
David Boaventura Gomes, Timo Rademakers, Ana Filipa Henriques Lourenço, Andrea Calore, Clarissa Tomasina, Denis van Beurden, Jinjie Venema, Bryan Chömpff, Hong Liu, Nicole Bouvy, Sandra Camarero‐Espinosa, Lorenzo Moroni   +11 more
wiley   +1 more source

Nanoparticles with Cell-Penetrating Peptides for Oral Delivery: A Case for Oral Delivery of Insulin. [PDF]

Int J Nanomedicine
Wang Y, Song W, Wang T, Sheng Y, Xue S, Dang Y, Rasool A, Zhang G.   +7 more
europepmc   +1 more source

Intrinsically Disordered Ku Protein-Derived Cell-Penetrating Peptides. [PDF]

ACS Bio Med Chem Au, 2023
Maity B, Moorthy H, Govindaraju T.
europepmc   +1 more source

Strategies to deliver peptide drugs to the brain [PDF]

, 2014
Lalatsa, Katerina, Schatzlein, Andreas G., Uchegbu, Ijeoma F.   +2 more
core   +1 more source