Results 71 to 80 of about 5,562,033 (283)
Membrane Active Peptides and Their Biophysical Characterization
Biomolecules, 2018 In the last 20 years, an increasing number of studies have been reported on membrane active peptides. These peptides exert their biological activity by interacting with the cell membrane, either to disrupt it and lead to cell lysis or to translocate ...
Fatma Gizem Avci +2 more
doaj +1 more source
Non-metabolic membrane tubulation and permeability induced by bioactive peptides. [PDF]
PLoS ONE, 2007 BACKGROUND:Basic cell-penetrating peptides are potential vectors for therapeutic molecules and display antimicrobial activity. The peptide-membrane contact is the first step of the sequential processes leading to peptide internalization and cell activity.
Antonin Lamazière +5 more
doaj +1 more source
Cell-penetrating Peptides [PDF]
Journal of Biological Chemistry, 2003 The present invention discloses cell penetrating peptides and conjugates of a cell penetrating peptide and a cargo molecule.
Jean Philippe Richard +7 more
openaire +1 more source
FEBS Open Bio, EarlyView.UiO‐66(Zr) metal–organic frameworks are chemically stable, biocompatible, and highly tunable nanomaterials. Their modular structure enables controlled drug delivery, multimodal bioimaging, and light‐activated photodynamic therapy, supporting integrated diagnostic and therapeutic (theranostic) applications in cancer and biomedical research.
Veronika Huntošová +2 more
wiley +1 more source
Synthesis, Structural and Biological Analysis of Organized Biomimetic Systems [PDF]
, 2010 As a part of a program for foldamer design two β-turn mimetics (3S)-amino-5-(carboxylmethyl)-2,3-dihydro-1,5-benzothiazepin-4(5H)-one or DBT and 2-aminomethyl-phenyl-acetic acid or AMPA were selected as frameworks from a molecular modeling study for ...
Lubomir, Vezenkov
core +1 more source
Evaluating the involvement of autolysosomes in the nuclear translocation of fluorescent proteins
FEBS Open Bio, EarlyView.Endogenously expressed fluorescent proteins can be degraded by autophagy and transported to cell nuclei via the nuclear pore complex. But in some cell lines, for example, HeLa cells which are positive for immunoreactivity of a receptor ligand, such as UCN I, in cell nuclei, fusion of autolysosome with the nuclear envelope is involved in the nuclear ...
Keiichi Ikeda
wiley +1 more source
Application of CPPs for Brain Delivery
, 2015 Cell-penetrating peptides provide a promising strategy for delivery of drugs across the blood-brain barrier. Here, we present an overview of CPP and peptide-mediated delivery to the central nervous system as well as a Transwell in vitro model to evaluate
Regberg, Jakob, +5 more
core +1 more source
Yeast Gcn2 retains activity following humanization of its auto‐phosphorylation region
FEBS Open Bio, EarlyView.Using Saccharomyces cerevisiae as a model to study Gcn2 activation and regulation is limited by the lack of antibodies detecting phosphorylated Gcn2. To overcome this, we engineered Gcn2‐HsC, a yeast Gcn2 variant recognizable by commercial anti‐human phospho‐GCN2 antibodies.
Reuben A. Anderson +2 more
wiley +1 more source
Characterisation of cell‐penetrating peptide‐mediated peptide delivery [PDF]
British Journal of Pharmacology, 2005 Cell‐penetrating peptides such as antennapedia, TAT, transportan and polyarginine have been extensively employed for in vitro and in vivo delivery of biologically active peptides. However, little is known of the relative efficacy, toxicity and uptake mechanism of individual protein transduction domain–peptide conjugates, factors that will be critical
Jones, Simon W. +6 more
openaire +2 more sources
The properties of cell penetrating peptides.
, 2019 The properties of cell penetrating peptides.
Atieh Hashemi (7610240) +2 more
core +1 more source