Results 111 to 120 of about 149 (146)

Surface dose analysis and dosimetric comparison of Halcyon versus Truebeam in breast cancer radiotherapy: An OSL dosimetry study

open access: yesJournal of Applied Clinical Medical Physics, EarlyView.
Abstract Purpose Breast cancer is a neoplastic disease with high prevalence among women. Radiotherapy is one of the principal treatment modalities for this disease, but it poses significant challenges. This study aimed to compare and evaluate the technical and dosimetric performance of conventional C‐arm linac systems and a new design, Halcyon, in the ...
Mustafa Çağlar   +8 more
wiley   +1 more source

A PANoptosis‐Based Signature for Survival and Immune Predication in Glioblastoma Multiforme

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective PANoptosis is a concept of total cell death characterized by pyroptosis, apoptosis, and necroptosis. We aimed to explore the clinical significance of PANoptosis‐related genes (PARGs) in glioblastoma multiforme (GBM). Methods Expression profiles of GBM were downloaded from the XENA database as a training dataset to construct a ...
Jun Yang   +4 more
wiley   +1 more source

Glycosylation Gene Signatures as Prognostic Biomarkers in Glioblastoma

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Glioblastoma (GBM) is an aggressive brain tumor characterized by significant heterogeneity. This study investigates the role of glycosylation‐related genes in GBM subtyping, prognosis, and response to therapy. Methods We analyzed mRNA expression data and clinical information from The Cancer Genome Atlas (TCGA) and Gene Expression ...
Tong Zhao   +4 more
wiley   +1 more source

An Analysis for IDH‐Mutant Grade 4 Astrocytoma Based on WHO CNS 5: Implication of Clinical Practice

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Purpose There is ongoing debate regarding the therapeutic approach and prognosis for IDH‐mutant grade 4 astrocytoma, a newly defined subtype of diffuse glioma in the 2021 WHO classification system for central nervous system tumors (WHO CNS 5). The aim of this study was to explore the clinical outcome and prognosticators for newly diagnosed IDH‐
Xianxin Qiu   +13 more
wiley   +1 more source

Whole‐Blood RNA Sequencing Profiling of Patients With Rheumatoid Arthritis Treated With Tofacitinib

open access: yesACR Open Rheumatology, EarlyView.
Objective Patients with rheumatoid arthritis (RA) often fail to respond to therapies, including JAK inhibitors (JAKi), and treatment allocation is made via a trial‐and‐error strategy. A comprehensive analysis of responses to JAKi, including tofacitinib, by RNA sequencing (RNAseq) would allow the discovery of transcriptomic markers with a two‐fold ...
Chiara Bellocchi   +11 more
wiley   +1 more source
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Oncogenes and cell proliferation

Current Opinion in Genetics & Development, 1995
Abstract The control of cell proliferation has an impact on both basic and practical problems in biology. Many of these problems intersect in the study of cancer biology, which is one organizing focus of this issue of Current Opinion in Genetics & Development.
Arnold J. Levine, James R. Broach
openaire   +7 more sources

Phosphoinositides and cell proliferation

Journal of Cell Science, 1985
ABSTRACT Certain growth factors act by stimulating the hydrolysis of inositol lipids to yield putative second messengers such as diacylglycerol (DG) and inositol trisphosphate (IP3). One function of the former is to stimulate C-kinase, which may act by switching on a sodium/hydrogen exchanger to induce the increase in pH that appears to ...
John P. Heslop   +3 more
openaire   +3 more sources

Calmodulin and cell proliferation

Biochemical and Biophysical Research Communications, 1982
Abstract The calmodulin content of synchronized Chinese hamster ovary (CHO-K 1 ) cells was determined at each phase of the cell cycle. The calmodulin content was minimum in the G 1 phase, increased after the cells entered S phase and reached the maximum level at the late G 2 or early M phase.
Hiroyoshi Hidaka, Yasuharu Sasaki
openaire   +3 more sources

Cell proliferation on hydrogels

In Vitro Cellular & Developmental Biology, 1990
The adhesion and proliferation of mammalian fibroblasts (Flow 7000) on the surface of hydrophilic (copolymer of N-vinyl-2-pyrrolidone and methyl methacrylate) and hydrophobic [polymethylmethacrylate (PMMA) stereocomplex] hydrogels with a wide range in water content were studied morphologically and quantitatively.
Shoji Nagaoka   +2 more
openaire   +2 more sources

Cell proliferation

The Journal of Pathology, 1991
AbstractThe composition of a series of critical summaries is necessarily idiosyncratic, but in this compliation I have been guided by the recent publication of reviews and monographs on the subject.1–3 consequently, it seems reasonable to focus on more fundamental areas of research which may lie outside the normal reading of most pathologists ...
openaire   +2 more sources

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