Results 101 to 110 of about 14,131,086 (234)

In wound repair vimentin mediates the transition of mesenchymal leader cells to a myofibroblast phenotype. [PDF]

open access: yes, 2018
Following injury, mesenchymal repair cells are activated to function as leader cells that modulate wound healing. These cells have the potential to differentiate to myofibroblasts, resulting in fibrosis and scarring.
Alnwibit, A. A.   +4 more
core   +1 more source

Irf6 directs glandular lineage differentiation of epidermal progenitors and promotes limited sweat gland regeneration in a mouse burn model

open access: yesStem Cell Research & Therapy, 2018
Background Damaged or malfunctioning sweat glands (SGs) after a burn injury would cause significant hyperthermia and even death, and there is an unmet need for effective treatment.
Bin Yao   +7 more
doaj   +1 more source

The Treatment of Neurodegenerative Disorders Using Umbilical Cord Blood and Menstrual Blood-Derived Stem Cells

open access: yesCell Transplantation, 2011
Stem cell transplantation is a potentially important means of treatment for a number of disorders. Two different stem cell populations of interest are mononuclear umbilical cord blood cells and menstrual blood-derived stem cells.
Paul R. Sanberg   +8 more
doaj   +1 more source

Evolutionary dynamics of adult stem cells: Comparison of random and immortal strand segregation mechanisms

open access: yes, 2004
This paper develops a point-mutation model describing the evolutionary dynamics of a population of adult stem cells. Such a model may prove useful for quantitative studies of tissue aging and the emergence of cancer.
A. T. Natarajan   +4 more
core   +1 more source

Targeting ectodysplasin promotor by CRISPR/dCas9-effector effectively induces the reprogramming of human bone marrow-derived mesenchymal stem cells into sweat gland-like cells

open access: yesStem Cell Research & Therapy, 2018
Background Patients with a deep burn injury are characterized by losing the function of perspiration and being unable to regenerate the sweat glands. Because of their easy accession, multipotency, and lower immunogenicity, bone marrow-derived mesenchymal
Sujing Sun   +6 more
doaj   +1 more source

Cells' puncture repair kit [PDF]

open access: yesThe Journal of Cell Biology, 2008
A cell with a torn or perforated membrane has to close the breach fast. To heal wounds inflicted by bacteria, cells rely on endocytosis, [Idone et al.][1] show. ![Figure][2] Endosomes contain either removed bacterial toxins (left) or damaged membrane (right).
openaire   +1 more source

Gain of 20q11.21 in human pluripotent stem cells enhances differentiation to retinal pigment epithelium

open access: yesStem Cell Research & Therapy
Background Cell therapies based on human pluripotent stem cells (hPSCs) are in clinical trials with the aim of restoring vision in people with age-related macular degeneration.
Loriana Vitillo   +7 more
doaj   +1 more source

Photoporation-mediated spatial intracellular delivery of stem cell-derived cardiomyocytes

open access: yesMethodsX
Human induced pluripotent stem cell-derived cardiomyocytes (iPSCCMs) are promising candidates for disease modeling and therapeutic purposes, however, non-viral intracellular delivery in these cells remains challenging.
Laurens Léger   +5 more
doaj   +1 more source

A novel splice variant of the DNA-PKcs gene is associated with clinical and cellular radiosensitvity in a xeroderma pigmentosum patient [PDF]

open access: yes, 2009
This article has been made available through the Brunel Open Access Publishing Fund.Background: Radiotherapy-induced DNA double strand breaks (DSB) are critical cytotoxic lesions.
Abbaszadeh, F   +9 more
core  

Home - About - Disclaimer - Privacy