Disruption of fusion results in mitochondrial heterogeneity and dysfunction [PDF]
, 2005 Mitochondria undergo continual cycles of fusion and fission, and the balance of these opposing processes regulates mitochondrial morphology. Paradoxically, cells invest many resources to maintain tubular mitochondrial morphology, when reducing both ...
Chan, David C. +2 more
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Біологічні студії, 2023 Background. Assessment of cell viability is crucial in cell studies. Testing plasma membrane integrity is a traditional approach of evaluating cell viability. Mitochondrial functional capacity closely correlates with plasma membrane integrity and overall
Anastasiia Zub +4 more
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Continuous chemotrophic growth and respiration of Chromatiaceae species at low oxygen concentrations [PDF]
, 1992 Endogenous and maximum respiration rates of nine purple sulfur bacterial strains were determined. Endogenous rates were below 10 nmol O2 · (mg protein · min)-1 for sulfur-free cells and 15–35 nmol O2 · (mg protein · min)-1 for cells containg ...
Overmann, Jörg, Pfennig, Norbert
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Role of Second Quinone Binding Site in Proton Pumping by Respiratory Complex I
Frontiers in Chemistry, 2019 Respiratory complex I performs the reduction of quinone (Q) to quinol (QH2) and pumps protons across the membrane. Structural data on complex I have provided spectacular insights into the electron and proton transfer paths, as well as into the long (~30 ...
Outi Haapanen +3 more
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The mycotoxin phomoxanthone A disturbs the form and function of the inner mitochondrial membrane. [PDF]
, 2018 Mitochondria are cellular organelles with crucial functions in the generation and distribution of ATP, the buffering of cytosolic Ca2+ and the initiation of apoptosis. Compounds that interfere with these functions are termed mitochondrial toxins, many of
Anand, Ruchika +25 more
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Living unicellular eukaryote Tetrahymena pyriformis as a model for study [PDF]
, 2011 Some animals are able to survive for a long time under conditions of drastically reduced oxidative metabolism, called metabolic depression. The most investigated type of metabolic depression is hibernation.
Elena Mokhova, Elena Mokhova
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THE RESPIRATION OF GROWING PLANT CELLS [PDF]
Plant Physiology, 1945 Growing cells of the hypocotyl of Helianthus seedlings were used, employing conditions identical with those of previous experiments cited above. The uppermost thirty-five millimeters of hypocotyl were cut in seven segments of uniform length (5 mm.). The region in which the cells were embryonic was not more than one millimeter long.
W, Donnelly, W A, Beck
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Lack of complex I activity in human cells carrying a mutation in MtDNA-encoded ND4 subunit is corrected by the Saccharomyces cerevisiae NADH-quinone oxidoreductase (NDI1) gene [PDF]
, 2001 The gene for the single subunit, rotenone-insensitive, and flavone-sensitive internal NADH-quinone oxidoreductase of Saccharomyces cerevisiae (NDI1) can completely restore the NADH dehydrogenase activity in mutant human cells that lack the essential ...
Attardi, Giuseppe +7 more
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Metformin promotes lifespan through mitohormesis via the peroxiredoxin PRDX-2 [PDF]
, 2014 The antiglycemic drug metformin, widely prescribed as first-line treatment of type II diabetes mellitus, has lifespan-extending properties. Precisely how this is achieved remains unclear.
Billen, Johan +8 more
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RESPIRATION OF RAT PERITONEAL MAST CELLS [PDF]
The Journal of Cell Biology, 1965 Methods for microgasometry of a few hundred mast cells are described. The Cartesian ampulla diver technique is used. The sample size is determined by counting the cells within the diver. The respiration rates at 37°C, expressed in microliters per cell per hour, are 0.29 x 10-6 without substrate and 0.47 x 10-6 with glucose.
N, Chakravarty, E, Zeuthen
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