Results 91 to 100 of about 14,296,855 (364)

Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?

open access: yesFEBS Letters, EarlyView.
This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes   +3 more
wiley   +1 more source

Sickle Cell Health Awareness, Perspectives, and Experiences (SHAPE) Survey: Perspectives of Physicians in Gulf Cooperation Council Countries on Sickle Cell Disease [PDF]

open access: bronze, 2023
Wasil Jastaniah   +7 more
openalex   +1 more source

Simultaneous characterization of cellular RNA structure and function with in-cell SHAPE-Seq

open access: yesNucleic Acids Research, 2015
Many non-coding RNAs form structures that interact with cellular machinery to control gene expression. A central goal of molecular and synthetic biology is to uncover design principles linking RNA structure to function to understand and engineer this ...
Kyle E. Watters   +2 more
semanticscholar   +1 more source

Cell Shape: Taking the Heat [PDF]

open access: yesCurrent Biology, 2008
Preservation of cell architecture under physically stressful conditions is a basic requirement for many biological processes and is critical for mechanosensory systems built to translate subtle changes in cell shape into changes in organism behaviour. A new study reveals how an extracellular protein--Spam--helps mechanosensory organs in the fruit fly ...
Kunda, Patricia   +2 more
openaire   +2 more sources

The role and implications of mammalian cellular circadian entrainment

open access: yesFEBS Letters, EarlyView.
At their most fundamental level, mammalian circadian rhythms occur inside every individual cell. To tell the correct time, cells must align (or ‘entrain’) their circadian rhythm to the external environment. In this review, we highlight how cells entrain to the major circadian cues of light, feeding and temperature, and the implications this has for our
Priya Crosby
wiley   +1 more source

CuticleTrace: A toolkit for capturing cell outlines from leaf cuticle with implications for paleoecology and paleoclimatology

open access: yesApplications in Plant Sciences
Premise Leaf epidermal cell morphology is closely tied to the evolutionary history of plants and their growth environments and is therefore of interest to many plant biologists. However, cell measurement can be time consuming and restrictive with current
Benjamin A. Lloyd   +6 more
doaj   +1 more source

Radially patterned cell behaviours during tube budding from an epithelium

open access: yeseLife, 2018
The budding of tubular organs from flat epithelial sheets is a vital morphogenetic process. Cell behaviours that drive such processes are only starting to be unraveled. Using live-imaging and novel morphometric methods, we show that in addition to apical
Yara E Sanchez-Corrales   +2 more
doaj   +1 more source

Orchestration of microtubules and the actin cytoskeleton in trichome cell shape determination by a plant-unique kinesin

open access: yeseLife, 2015
Microtubules (MTs) and actin filaments (F-actin) function cooperatively to regulate plant cell morphogenesis. However, the mechanisms underlying the crosstalk between these two cytoskeletal systems, particularly in cell shape control, remain largely ...
Juan Tian   +7 more
semanticscholar   +1 more source

Matrix mimics shape cell studies [PDF]

open access: yesNature, 2019
The extracellular matrix governs a surprising number of cellular functions. New techniques are revealing how cells and matrix communicate — and why this cross-talk matters. The extracellular matrix governs a surprising number of cellular functions. New techniques are revealing how cells and matrix communicate — and why this cross-talk matters.
openaire   +2 more sources

Shaping the Archaeal Cell Envelope [PDF]

open access: yesArchaea, 2010
Although archaea have a similar cellular organization as other prokaryotes, the lipid composition of their membranes and their cell surface is unique. Here we discuss recent developments in our understanding of the archaeal protein secretion mechanisms, the assembly of macromolecular cell surface structures, and the release of S-layer-coated vesicles ...
Ellen, Albert F.   +3 more
openaire   +5 more sources

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