Results 161 to 170 of about 2,922,174 (317)

Focused Size Selection of Cell-Free DNA Samples for Liquid Biopsy Applications that Rely on Next-Generation Sequencing

, 2019
Christopher K. Raymond
openalex   +1 more source

Cis‐regulatory and long noncoding RNA alterations in breast cancer – current insights, biomarker utility, and the critical need for functional validation

Molecular Oncology, EarlyView.
The noncoding region of the genome plays a key role in regulating gene expression, and mutations within these regions are capable of altering it. Researchers have identified multiple functional noncoding mutations associated with increased cancer risk in the genome of breast cancer patients.
Arnau Cuy Saqués, Aracele Martinez‐Mendez, John Crown, Alex Eustace   +3 more
wiley   +1 more source

Hyperaminoacidemia from interrupted glucagon signaling increases pancreatic acinar cell proliferation and size via mTORC1 and YAP pathways

Chunhua Dai, Yue Zhang, Yulong Gong, Amber Bradley, Zihan Tang, Katelyn Sellick, Shristi Shrestha, Erick Spears, Brittney A. Covington, Jade Stanley, Regina Jenkins, Tiffany M. Richardson, REBEKAH BRANTLEY, Katie C. Coate, Diane C. Saunders, J. J. Wright, Marcela Briššová, E. Danielle Dean, Alvin C. Powers, Wenbiao Chen   +19 more
openalex   +1 more source

Methylation biomarkers can distinguish pleural mesothelioma from healthy pleura and other pleural pathologies

Molecular Oncology, EarlyView.
We developed and validated a DNA methylation–based biomarker panel to distinguish pleural mesothelioma from other pleural conditions. Using the IMPRESS technology, we translated this panel into a clinically applicable assay. The resulting two classifier models demonstrated excellent performance, achieving high AUC values and strong diagnostic accuracy.
Janah Vandenhoeck, Nele De Meulenaere, Thomas Vanpoucke, Joe Ibrahim, Dieter Peeters, Suresh Krishan Yogeswaran, Wen Wen, Paul Van Schil, Jeroen M. H. Hendriks, Jo Raskin, Jan van Meerbeeck, Guy Van Camp, Ken Op de Beeck   +12 more
wiley   +1 more source

The G1/S transition in mammalian stem cells in vivo is autonomously regulated by cell size. [PDF]

Nat Commun
Xie S, Zhang S, de Medeiros G, Liberali P, Skotheim JM.   +4 more
europepmc   +1 more source

Microgravity Significantly Influences Neural Stem Cells Size and Numbers: Implications for Long-term Space Missions

, 2021
Sophia Shaka, Nicolas Carpo, Victoria Tran, Carlos Cepeda, Araceli Espinosa‐Jeffrey   +4 more
openalex   +1 more source

Strength through diversity: how cancers thrive when clones cooperate

Molecular Oncology, EarlyView.
Intratumor heterogeneity can offer direct benefits to the tumor through cooperation between different clones. In this review, Kuiken et al. discuss existing evidence for clonal cooperativity to identify overarching principles, and highlight how novel technological developments could address remaining open questions.
Marije C. Kuiken, Maartje Witsen, Emile E. Voest, Krijn K. Dijkstra   +3 more
wiley   +1 more source

Is cell size a spandrel?

, 2017
Ariel Amir
openalex   +1 more source

Detection of circulating tumor DNA in colorectal cancer patients using a methylation‐specific droplet digital PCR multiplex

Molecular Oncology, EarlyView.
We developed a cost‐effective methylation‐specific droplet digital PCR multiplex assay containing tissue‐conserved and tumor‐specific methylation markers. The assay can detect circulating tumor DNA with high accuracy in patients with localized and metastatic colorectal cancer.
Luisa Matos do Canto, Louise Raunkilde, Jan Lindebjerg, Mads Malik Aagaard, Christina Therkildsen, Jakob Kleif, Lars Henrik Jensen, Torben Frøstrup Hansen, Rikke Fredslund Andersen   +8 more
wiley   +1 more source

Clinically feasible liver tumour cell size measurement through histology-informed in vivo diffusion MRI. [PDF]

Commun Med (Lond)
Grussu F, Grigoriou A, Bernatowicz K, Palombo M, Casanova-Salas I, Navarro-Garcia D, Barba I, Simonetti S, Serna G, Macarro C, Voronova AK, Garay V, Corral JF, Vidorreta M, García-Polo García P, Merino X, Mast R, Rosón N, Escobar M, Vieito M, Toledo R, Nuciforo P, Mateo J, Garralda E, Perez-Lopez R.   +24 more
europepmc   +1 more source