Results 171 to 180 of about 5,248,930 (285)

Consideration of Grid Cell Size to Represent Stream Networks for the Conterminous United States. [PDF]

Ground Water
Fleming BJ, Belitz K, Killian CD.
europepmc   +1 more source

Targeting the AKT/mTOR pathway attenuates the metastatic potential of colorectal carcinoma circulating tumor cells in a murine xenotransplantation model

Molecular Oncology, EarlyView.
Dual targeting of AKT and mTOR using MK2206 and RAD001 reduces tumor burden in an intracardiac colon cancer circulating tumor cell xenotransplantation model. Analysis of AKT isoform‐specific knockdowns in CTC‐MCC‐41 reveals differentially regulated proteins and phospho‐proteins by liquid chromatography coupled mass spectrometry. Circulating tumor cells
Daniel J. Smit, Thais Pereira‐Veiga, Helena Brauer, Michael Horn, Paula Nissen, Thomas Mair, Bente Siebels, Hannah Voß, Ruimeng Zhuang, Marie‐Therese Haider, Desiree Loreth, Margarita Iskhakova, Bele Lindemann, Julian Kött, Laure Cayrefourcq, Jasmin Wellbrock, Hartmut Schlüter, Klaus Pantel, Catherine Alix‐Panabières, Manfred Jücker   +19 more
wiley   +1 more source

Heat shock transcription factor-mediated thermal tolerance and cell size plasticity in marine diatoms. [PDF]

Nat Commun
Huang D, Cheng CQ, Zhang HY, Huang Y, Li SY, Huang YT, Huang XL, Pei LL, Luo Z, Zou LG, Yang WD, Zheng XF, Li DW, Li HY.   +13 more
europepmc   +1 more source

Cell Size Contributes to Single-Cell Proteome Variation. [PDF]

J Proteome Res, 2023
Lanz MC, Fuentes Valenzuela L, Elias JE, Skotheim JM.   +3 more
europepmc   +1 more source

Interplay of integrins and selectins in metastasis

Molecular Oncology, EarlyView.
Here we review the role of integrins and their interplay with selectins in metastasis. The efficacy of integrin‐targeted therapies may be reduced in tumors where metastasis relies heavily on selectins. In certain tumors, integrins and selectins exhibit a synergistic interaction during intraperitoneal dissemination.
Diana Maltseva, Ashot Nersisyan, Alexander Tonevitsky   +2 more
wiley   +1 more source

Swi4-dependent SWI4 transcription couples cell size to cell cycle commitment. [PDF]

iScience
Goswami P, Ghimire A, Coffin C, Cheng J, Coulombe-Huntington J, Ghazal G, Thattikota Y, Guerra MF, Tyers M, Tollis S, Royer CA.   +10 more
europepmc   +1 more source

Inhibitor of DNA binding‐1 is a key regulator of cancer cell vasculogenic mimicry

Molecular Oncology, EarlyView.
Elevated expression of transcriptional regulator inhibitor of DNA binding 1 (ID1) promoted cancer cell‐mediated vasculogenic mimicry (VM) through regulation of pro‐angiogenic and pro‐cancerous genes (e.g. VE‐cadherin (CDH5), TIE2, MMP9, DKK1). Higher ID1 expression also increased metastases to the lung and the liver.
Emma J. Thompson, Emma L. Dorward, Kristyn Jurrius, Nathalie Nataren, Markus Tondl, Kay K. Myo Min, Michaelia P. Cockshell, Anahita Fouladzadeh, John Toubia, Mark DeNichilo, Delphine Merino, Claudine S. Bonder   +11 more
wiley   +1 more source

Cell size explains shift in phytoplankton community structure following storm-induced changes in light and nutrients. [PDF]

Ecology
Guislain ALN, Nejstgaard JC, Köhler J, Sperfeld E, Mischke U, Skjelbred B, Grossart HP, Lyche Solheim A, Gessner MO, Berger SA.   +9 more
europepmc   +1 more source

MET and NF2 alterations confer primary and early resistance to first‐line alectinib treatment in ALK‐positive non‐small‐cell lung cancer

Molecular Oncology, EarlyView.
Alectinib resistance in ALK+ NSCLC depends on treatment sequence and EML4‐ALK variants. Variant 1 exhibited off‐target resistance after first‐line treatment, while variant 3 and later lines favored on‐target mutations. Early resistance involved off‐target alterations, like MET and NF2, while on‐target mutations emerged with prolonged therapy.
Jie Hu, Ning Ding, Xiaobo Xu, Yedan Chen, Yong Zhang, Jingwen Liu, Jiebai Zhou, Hairong Bao, Donghui Zhang, Yijun Song, Yang Shao, Yuanlin Song   +11 more
wiley   +1 more source

The CIN-TCP transcription factors regulate endocycle progression and pavement cell size by promoting cell wall pectin degradation. [PDF]

Nat Commun
Shen F, Zhang H, Wan M, Yang Y, Kuang Z, Xiao L, Zuo D, Li Z, Qin G, Li L.   +9 more
europepmc   +1 more source