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Cell size: Single cells illuminate the rules of cell size control
Current Biology, 2023A new study uses Chlamydomonas reinhardtii to understand how cell size homeostasis emerges from stochastic individual cell behaviors within a population. The authors find that a simple power law model was a poor predictor of cell size regulation; rather, it is better explained by a modified threshold model.
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Why size matters: altering cell size
Current Opinion in Genetics & Development, 2002Several genes involved in growth control have lately been demonstrated to exhibit more potent effects on cell size than on cell proliferation. Many of these genes direct protein and ribosomal synthesis, highlighting the interdependence between cell size and macromolecular content.
Leslie J, Saucedo, Bruce A, Edgar
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Dielectrophoresis of cell-size liposomes
Biochimica et Biophysica Acta (BBA) - Biomembranes, 1994The dielectrophoresis (DEP) behavior of cell size liposomes were studied in the frequency range from 20 kHz to 3 MHz. Liposomes in the size of about 10 microns in diameter were made from egg phosphatidylcholine (PC), egg phosphatidylethanolamine (PE), egg phosphatidylglycerol (PG) and brain phosphatidylserine (PS).
N G, Stoicheva, S W, Hui
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BioEssays, 2000
For many years, it has been believed that diffusion is the principle motive force for distributing molecules within the cell. Yet, our current information about the cell makes this improbable. Furthermore, the argument that limitations responsible for the relative constancy of cell size--which seldom varies by more than a factor of 2, whereas organisms
P S, Agutter, D N, Wheatley
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For many years, it has been believed that diffusion is the principle motive force for distributing molecules within the cell. Yet, our current information about the cell makes this improbable. Furthermore, the argument that limitations responsible for the relative constancy of cell size--which seldom varies by more than a factor of 2, whereas organisms
P S, Agutter, D N, Wheatley
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Nature Materials, 2018
Macrophage confinement reduces the ‘late’ inflammatory gene response to lipopolysaccharide through myocardin-related transcription factor, an actin-binding transcription factor.
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Macrophage confinement reduces the ‘late’ inflammatory gene response to lipopolysaccharide through myocardin-related transcription factor, an actin-binding transcription factor.
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Annual Review of Genetics, 2019
The genetic control of the characteristic cell sizes of different species and tissues is a long-standing enigma. Plants are convenient for studying this question in a multicellular context, as their cells do not move and are easily tracked and measured from organ initiation in the meristems to subsequent morphogenesis and differentiation.
Marco, D'Ario, Robert, Sablowski
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The genetic control of the characteristic cell sizes of different species and tissues is a long-standing enigma. Plants are convenient for studying this question in a multicellular context, as their cells do not move and are easily tracked and measured from organ initiation in the meristems to subsequent morphogenesis and differentiation.
Marco, D'Ario, Robert, Sablowski
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Trends in Genetics, 2002
To remain viable, cells have to coordinate cell growth with cell division. In yeast, this occurs at two control points: the boundaries between G1 and S phases, also known as Start, and between G2 and M phases. Theoretically, coordination can be achieved by independent regulation of growth and division, or by participation of surveillance mechanisms in ...
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To remain viable, cells have to coordinate cell growth with cell division. In yeast, this occurs at two control points: the boundaries between G1 and S phases, also known as Start, and between G2 and M phases. Theoretically, coordination can be achieved by independent regulation of growth and division, or by participation of surveillance mechanisms in ...
exaly +3 more sources