Results 211 to 220 of about 3,250,985 (308)

ATP increases murine neuroblastoma cell size through a PANX1- and macropinocytosis-dependent mechanism. [PDF]

Biol Open
Boyce AKJ, You H, Wicki-Stordeur LE, Swayne LA.   +3 more
europepmc   +1 more source

mRNA trafficking directs cell-size-scaling of mitochondria distribution and function. [PDF]

Nat Commun
Bradbury JJ, Hulmes GE, Viswanathan R, Costa G, Lovegrove HE, Herbert SP.   +5 more
europepmc   +2 more sources

Promiscuous stimulation of HSP70 ATPase activity by parasite‐derived J‐domains

FEBS Open Bio, EarlyView.
The malaria parasite Plasmodium falciparum exports three highly homologous yet functionally divergent J‐domain proteins into human erythrocytes. Here, we show that J‐domains isolated from all three proteins effectively stimulate the ATPase activity of both endogenous host and exported parasite HSP70 chaperones.
Julian Barth, Moritz Koch, Le‐Han Rössner, Johanna Eichhorn, Denys Pogoryelov, Matthias P. Mayer, Jude M. Przyborski   +6 more
wiley   +1 more source

Visceral, Not Abdominal Subcutaneous, Fat Cell Size Associates with Metabolic Dysfunction-Associated Liver Disease in Severe Obesity. [PDF]

Obes Facts
Tremblay EJ, Biertho L, Lebel S, Couture CY, Maltais-Payette I, Ostinelli G, Gauthier MF, Lajeunesse-Trempe F, Mauriège P, Tchernof A.   +9 more
europepmc   +1 more source

Identification of functional murine mitochondrial formyl peptides and their effects on myeloid‐derived suppressor cell generation

FEBS Open Bio, EarlyView.
We first identified functional murine mitochondrial N‐formyl peptides (MT‐FPs) and investigated their effects on the in vitro myeloid‐derived suppressor cell (MDSC) generation from bone marrow cells. We demonstrated that MT‐FPs acted directly on bone marrow cells to promote MDSC generation and modulated the polymorphonuclear (PMN)‐MDSC/monocyte (M ...
Miyako Ozawa, Saori Kagoshima, Akira Yamada   +2 more
wiley   +1 more source

Applicability of mitotic figure counting by deep learning: a development and pan‐cancer validation study

FEBS Open Bio, EarlyView.
In this study, we developed a deep learning method for mitotic figure counting in H&E‐stained whole‐slide images and evaluated its prognostic impact in 13 external validation cohorts from seven different cancer types. Patients with more mitotic figures per mm2 had significantly worse patient outcome in all the studied cancer types except colorectal ...
Joakim Kalsnes, Maria X. Isaksen, Frida Julbø, Manohar Pradhan, Andreas Kleppe, Sepp De Raedt, Ole‐Johan Skrede, Turid Torheim, John Arne Nesheim, Hans Martin Mohn, Hanne A. Askautrud, Karolina Cyll, Wanja Kildal, Emma Rewcastle, Melinda Lillesand, Vebjørn Kvikstad, Emiel Janssen, Robert Jones, Odd Terje Brustugun, Bjørn Brennhovd, Erik Skaaheim Haug, Lill‐Tove Rasmussen Busund, Elin Richardsen, Sigve Andersen, Tom Dønnem, Kristina Lindemann, Gunnar Kristensen, Neil A. Shepherd, Marco Novelli, Knut Liestøl, David Kerr, Håvard E. Danielsen, Tarjei S. Hveem   +32 more
wiley   +1 more source

Repeatability of in vivo MR cytometry for measuring cell size and density in healthy human livers. [PDF]

Magn Reson Imaging
Jiang X, Jin C, Kang H, Piantek G, Zu Z, Gore JC, Xu J.   +6 more
europepmc   +1 more source

Single‐molecule DNA flow‐stretch assays for high‐throughput DNA–protein interaction studies

FEBS Open Bio, EarlyView.
We describe an optimised single‐molecule DNA flow‐stretch assay that visualises DNA–protein interactions in real time. Linear DNA fragments are tethered to a surface and stretched by buffer flow for fluorescence imaging. Using λ and φX174 DNA, this protocol enhances reproducibility and accessibility, providing a versatile approach for studying diverse ...
Ayush Kumar Ganguli, Mohammad Nour Alsamsam, Ugnė Bagdonaitė, Van Truc Vu, Chun‐Jen Huang, Polina Kuzhir, Mindaugas Zaremba, Aurimas Kopūstas, Marijonas Tutkus   +8 more
wiley   +1 more source

Nanosecond pulsed electric fields induce cell-size-dependent selective permeabilization of urothelial cancer cells. [PDF]

Commun Biol
Kielbik A, Hellwich E, Bahlinger V, Sowa P, Lambton D, Kühs M, Barcena ML, Vakhrusheva O, Proebsting H, Walz S, Schäffer TE, Fend F, Novickij V, Amend B, Tsaur I.   +14 more
europepmc   +1 more source

Metabolic pathways further increase the complexity of cell size control in budding yeast

Microbial Cell, 2014
Jorrit M. Enserink
doaj   +1 more source