Results 11 to 20 of about 1,961,065 (268)
Rapid Delivery of Gold Nanoparticles into Colon Cancer HT-29 Cells by Electroporation: In-vitro Study [PDF]
Journal of Biomedical Physics and Engineering, 2020 Background: Electroporation has become a routine technique for rapid drug delivery for the treatment of cancer. Because of its simplicity and wide range of application, it has been applied for the transfer of gold-nanoparticles and can facilitate entry ...
Z Arab-Bafrani +2 more
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Cell Death and Disease, 2022 Cancer genomics and cancer mutation databases have made an available wealth of information about missense mutations found in cancer patient samples. Contextualizing by means of annotation and predicting the effect of amino acid change help identify which
Matteo Tiberti +6 more
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Amino Acid Activation of mTORC1 by a PB1-Domain-Driven Kinase Complex Cascade
Cell Reports, 2015 The mTORC1 complex is central to the cellular response to changes in nutrient availability. The signaling adaptor p62 contributes to mTORC1 activation in response to amino acids and interacts with TRAF6, which is required for the translocation of mTORC1 ...
Juan F. Linares +6 more
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CDDO and ATRA Instigate Differentiation of IMR32 Human Neuroblastoma Cells
Frontiers in Molecular Neuroscience, 2017 Neuroblastoma is the most common solid extra cranial tumor in infants. Improving the clinical outcome of children with aggressive tumors undergoing one of the multiple treatment options has been a major concern.
Namrata Chaudhari +3 more
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Cancer cells survive with survivin
Cancer Science, 2008 Survivin has multiple functions including cytoprotection, inhibition of cell death, and cell‐cycle regulation, especially at the mitotic process stage, all of which favor cancer survival. Many studies on clinical specimens have shown that survivin expression is invariably up‐regulated in human cancers and is associated with resistance to chemotherapy ...
Hirofumi, Yamamoto +2 more
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p63, Cell Adhesion and Survival [PDF]
Cell Cycle, 2007 The development of stratified epithelia and their derivatives is a complex process requiring a multifaceted transcriptional program. p63, the p53-related transcription factor, is fundamental to this process. However, the underlying mechanisms by which p63 exerts its influence on stratified epithelial development and integrity remain elusive.
Danielle K, Carroll +2 more
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Cell Transplantation, 1995 Tissue storage prior to intracerebral transplantation would represent a major advantage when conducting clinical transplantation trials in that the procurement of the embryonic donor tissue and the timing of neurosurgery could be planned more efficiently.
Eva M. Frodl +3 more
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Frontiers in Physiology, 2020 Dementia is one among the consequences of aging, and amnesia is often one of the most common symptoms. The lack of memory, as a consequence of both “healthy” aging or neurodegenerative conditions, such as in Alzheimer’s disease, has a dramatic impact on ...
Flavia Messina +4 more
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Autophagy in Viral Development and Progression of Cancer
Frontiers in Oncology, 2021 Autophagy is a complex degradative process by which eukaryotic cells capture cytoplasmic components for subsequent degradation through lysosomal hydrolases.
Alejandra Suares +5 more
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Reduced hippocampal neurogenesis in R6/2 transgenic Huntington's disease mice
Neurobiology of Disease, 2005 We investigated whether cell proliferation and neurogenesis are altered in R6/2 transgenic Huntington's disease mice. Using bromodeoxyuridine (BrdU), we found a progressive decrease in the number of proliferating cells in the dentate gyrus of R6/2 mice ...
Joana M.A.C. Gil +6 more
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