Results 31 to 40 of about 8,088,933 (310)
Frontiers in Cell and Developmental Biology, 2022 Humanin (HN) belongs to a member of mitochondrial-derived peptides (MDPs) which are encoded by mitochondrial genes. HN shares sequence homology with thirteen HN-like proteins, named MTRNR2L1 to MTRNR2L13, which encompass 24–28 amino acid residues in ...
Sipin Zhu +4 more
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Effects of zinc oxide and calcium–doped zinc oxide nanocrystals on cytotoxicity and reactive oxygen species production in different cell culture models [PDF]
Restorative Dentistry & Endodontics, 2020 ObjectivesThis study aimed to synthesize nanocrystals (NCs) of zinc oxide (ZnO) and calcium ion (Ca2+)-doped ZnO with different percentages of calcium oxide (CaO), to evaluate cytotoxicity and to assess the effects of the most promising NCs on ...
Gabriela Leite de Souza +7 more
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The PDGF/VEGF Receptor Controls Blood Cell Survival in Drosophila
, 2019 The Drosophila PDGF/VEGF receptor (PVR) has known functions in the guidance of cell migration. We now demonstrate that during embryonic hematopoiesis, PVR has a role in the control of antiapoptotic cell survival.
Brückner, Katja +5 more
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Frontiers in Physiology, 2020 Dementia is one among the consequences of aging, and amnesia is often one of the most common symptoms. The lack of memory, as a consequence of both “healthy” aging or neurodegenerative conditions, such as in Alzheimer’s disease, has a dramatic impact on ...
Flavia Messina +4 more
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Reduced hippocampal neurogenesis in R6/2 transgenic Huntington's disease mice
Neurobiology of Disease, 2005 We investigated whether cell proliferation and neurogenesis are altered in R6/2 transgenic Huntington's disease mice. Using bromodeoxyuridine (BrdU), we found a progressive decrease in the number of proliferating cells in the dentate gyrus of R6/2 mice ...
Joana M.A.C. Gil +6 more
doaj +1 more source
AKT signaling mediates IGF-I survival actions on otic neural progenitors [PDF]
, 2012 Background: Otic neurons and sensory cells derive from common progenitors whose transition into mature cells requires the coordination of cell survival, proliferation and differentiation programmes.
Sanchez-Calderon, Hortensia +19 more
core +2 more sources
BECLIN-1/BECN1 at the barrier: a gatekeeper of epithelial and endothelial homeostasis
Autophagy ReportsEpithelial and endothelial barriers are essential for tissue homeostasis, protecting the body from environmental insults while regulating selective transport. The integrity of these barriers relies on dynamic intercellular junctions whose composition and
Juliani Juliani +2 more
doaj +1 more source
Studies on the role of Coronin 1 and the actin cytoskeleton in T cell signaling and survival [PDF]
, 2009 Calcium ions (Ca2+) function as universal second messengers in most if not all eukaryotic cells, including the cells of the immunesystem. Ca2+ signals are required for the proper activation of lymphocytes, such as T-lymphocytes, their proliferation ...
Müller, Philipp
core +1 more source
Autophagy ReportsDisrupted intestinal homeostasis and barrier function contribute to the development of diseases such as inflammatory bowel disease. BECLIN-1, a core component of two class III phosphatidylinositol 3 kinase complexes, has a dual role in autophagy and ...
Juliani Juliani +10 more
doaj +1 more source
Spatiotemporal evolution of early innate immune responses triggered by neural stem cell grafting [PDF]
, 2012 INTRODUCTION: Transplantation of neural stem cells (NSCs) is increasingly suggested to become part of future therapeutic approaches to improve functional outcome of various central nervous system disorders. However, recently it has become clear that only
Van Der Linden, Anne-Marie +24 more
core +1 more source