Results 41 to 50 of about 2,251,671 (317)

Poly(ADP-ribose) polymerase family member 14 (PARP14) is a novel effector of the JNK2-dependent pro-survival signal in multiple myeloma [PDF]

, 2013
Copyright @ 2013 Macmillan Publishers Limited. This is the author's accepted manuscript. The final published article is available from the link below.Regulation of cell survival is a key part of the pathogenesis of multiple myeloma (MM).
Papa, S, Rahemtulla, A, Chaidos, A, Barbarulo, A, Karadimitris, A, Iansante, V, Naresh, K, Haskard, DO, Bubici, C, Franzoso, G   +9 more
core   +1 more source

Programming plasma cell survival [PDF]

Journal of Experimental Medicine, 2014
![Figure][1] Insight from Ulf Klein In this issue, two independent groups show that the transcription factor ZBTB20 is required for the maintenance of long-lived plasma cells following immunization with the commonly used adjuvant, alum.
openaire   +2 more sources

Clinical and Biological Features of Response in Resistant Neuroblastoma to 131I‐Metaiodobenzylguanidine Radiotherapy in the Anti‐GD2 Immunotherapy Era

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background 131I‐metaiodobenzylguanidine (131I‐MIBG) radiotherapy is a key treatment for relapsed and refractory (R/R) neuroblastoma (NB). Patients with R/R disease treated in the modern era are increasingly exposed to anti‐GD2 immunotherapy, which exerts selective pressure and may modify both tumor cell state and microenvironment.
Benjamin J. Lerman, Katherine K. Matthay, Fabienne Hollinger, Catriona Black, Ann A. Lazar, Miguel Pampaloni, Steven G. DuBois, Kieuhoa T. Vo   +7 more
wiley   +1 more source

A LisH-domain protein interaction map reveals a Lis1-ARIH2-dynein regulatory axis

iScience
Summary: LisH-domain-containing proteins are involved in diverse cellular processes and disease mechanisms, yet their functional interaction landscape remains poorly characterized.
Devanshi Gupta, Subbareddy Maddika
doaj   +1 more source

The Role of Insulin-Like Growth Factor-2 on the Cellular Viability and Differentiation to the Osteogenic Lineage and Mineralization of Stem Cells Cultured on Deproteinized Bovine Bone Mineral

Applied Sciences, 2020
Insulin-like growth factors (IGFs) plays various roles, including differentiation and mitogenesis, and IGFs are reported to regulate the bone growth and maintenance.
Hyunjin Lee, Sae Kyung Min, Yoon-Hee Park, Jun-Beom Park   +3 more
doaj   +1 more source

Melatonin Ameliorates Apoptosis of A549 Cells Exposed to Chicken House PM_2.5: A Novel Insight in Poultry Production

Toxics, 2023
The particulate matter 2.5 (PM2.5) from the chicken production system can cause lung injury and reduce productivity through prolonged breath as it attaches large amounts of harmful substances and microbes.
Pengyuan Dai, Jiakun Shen, Dan Shen, Xiaotong Li, Tin-Tin Win-Shwe, Chunmei Li   +5 more
doaj   +1 more source

Signalling for B cell survival. [PDF]

, 2017
The number of mature B cells is carefully controlled by signalling from receptors that support B cell survival. The best studied of these are the B cell antigen receptor (BCR) and BAFFR.
Tybulewicz, VL, Schweighoffer, E
core   +1 more source

Deep Sequencing of FLT3‐ITD Enables Response Evaluation and Post‐Treatment Monitoring in Childhood AML: An Exploratory Study

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background An internal tandem duplication in the gene encoding Fms‐like tyrosine kinase 3 (FLT3‐ITD) is associated with high relapse risk and poor prognosis in acute myeloid leukemia (AML) and plays a crucial role in treatment decisions. Measurable residual disease (MRD) analysis of FLT3‐ITD during and after treatment has shown prognostic ...
Sofie Johansson Alm, Bea Tornberg, Erik Delsing Malmberg, Henrik Hasle, Kristian Løvvik Juul‐Dam, Lars Palmqvist, Borhan R. Saeed, Giti Shah Barkhordar, Anastasia Soboli, Anna Staffas, Jonas Abrahamsson, Linda Fogelstrand   +11 more
wiley   +1 more source

Renalase: A Multi-Functional Signaling Molecule with Roles in Gastrointestinal Disease

Cells, 2021
The survival factor renalase (RNLS) is a recently discovered secretory protein with potent prosurvival and anti-inflammatory effects. Several evolutionarily conserved RNLS domains are critical to its function.
Thomas C. Pointer, Fred S. Gorelick, Gary V. Desir   +2 more
doaj   +1 more source

Nel positively regulates the genesis of retinal ganglion cells by promoting their differentiation and survival during development [PDF]

, 2014
Peer ...
Findlay, Amy S., Ouyang, Zhufeng, Zakrewska, Ewa, Kuan, Soh-Leh, Durward, Elaine, Nakamoto, Masaru, Findlay, Amy, Zakrzewska, Ewa, Nakamoto, Chizu, Kuan, Soh Leh, Endo, Takuma   +10 more
core   +1 more source