Results 21 to 30 of about 2,251,671 (317)
Survival of auditory hair cells [PDF]
Cell and Tissue Research, 2015 The inability of mammals to regenerate auditory hair cells creates a pressing need to understand the means of enhancing hair cell survival following insult or injury. Hair cells are easily damaged by noise exposure, by ototoxic medications and as a consequence of aging processes, all of which lead to progressive and permanent hearing impairment as hair
Michelle L, Seymour, Fred A, Pereira
openaire +2 more sources
PTEN Regulates Glucose Transporter Recycling by Impairing SNX27 Retromer Assembly
Cell Reports, 2017 Summary: The tumor suppressor PTEN executes cellular functions predominantly through its phosphatase activity. Here we identified a phosphatase-independent role for PTEN during vesicular trafficking of the glucose transporter GLUT1.
Swapnil Rohidas Shinde +1 more
doaj +1 more source
Chromosome 9p deletion in clear cell renal cell carcinoma predicts recurrence and survival following surgery [PDF]
, 2014 Background:Wider clinical applications of 9p status in clear cell renal cell carcinoma (ccRCC) are limited owing to the lack of validation and consensus for interphase fluorescent in situ hybridisation (I-FISH) scoring technique.
Fleming, S. +15 more
core +1 more source
Cell Transplantation, 1995 Tissue storage prior to intracerebral transplantation would represent a major advantage when conducting clinical transplantation trials in that the procurement of the embryonic donor tissue and the timing of neurosurgery could be planned more efficiently.
Eva M. Frodl +3 more
doaj +1 more source
Expression of CXCL10 is associated with response to radiotherapy and overall survival in squamous cell carcinoma of the tongue [PDF]
, 2014 Five-year survival for patients with oral cancer has been disappointingly stable during the last decades, creating a demand for new biomarkers and treatment targets.
Philip John Coates +17 more
core +1 more source
The PDGF/VEGF Receptor Controls Blood Cell Survival in Drosophila
, 2019 The Drosophila PDGF/VEGF receptor (PVR) has known functions in the guidance of cell migration. We now demonstrate that during embryonic hematopoiesis, PVR has a role in the control of antiapoptotic cell survival.
Brückner, Katja +5 more
core +1 more source
Cancer cells survive with survivin
Cancer Science, 2008 Survivin has multiple functions including cytoprotection, inhibition of cell death, and cell‐cycle regulation, especially at the mitotic process stage, all of which favor cancer survival. Many studies on clinical specimens have shown that survivin expression is invariably up‐regulated in human cancers and is associated with resistance to chemotherapy ...
Hirofumi, Yamamoto +2 more
openaire +2 more sources
Frontiers in Physiology, 2020 Dementia is one among the consequences of aging, and amnesia is often one of the most common symptoms. The lack of memory, as a consequence of both “healthy” aging or neurodegenerative conditions, such as in Alzheimer’s disease, has a dramatic impact on ...
Flavia Messina +4 more
doaj +1 more source
Autophagy in Viral Development and Progression of Cancer
Frontiers in Oncology, 2021 Autophagy is a complex degradative process by which eukaryotic cells capture cytoplasmic components for subsequent degradation through lysosomal hydrolases.
Alejandra Suares +5 more
doaj +1 more source
Gene trapping identifies transiently induced survival genes during programmed cell death
, 2001 Background: The existence of a constitutively expressed machinery for death in individual cells has led to the notion that survival factors repress this machinery and, if such factors are unavailable, cells die by default.
Yang, Ji-Yeon +3 more
core +1 more source