Results 271 to 280 of about 14,964,075 (408)

A Low Oxygen-enhancement Ratio for Tumour-cell Survival as Compared with that for Tumour-growth Delay [PDF]

, 1972
Nicolas J. McNally
openalex   +1 more source

Landscape of BRAF transcript variants in human cancer

Molecular Oncology, EarlyView.
We investigate the annotation of BRAF variants, focusing on protein‐coding BRAF‐220 (formerly BRAF‐reference) and BRAF‐204 (BRAF‐X1). The IsoWorm pipeline allows us to quantify these variants in human cancer, starting from RNA‐sequencing data. BRAF‐204 is more abundant than BRAF‐220 and impacts patient survival.
Maurizio S. Podda, Danilo Tatoni, Gianluca Mattei, Alberto Magi, Romina D'Aurizio, Laura Poliseno   +5 more
wiley   +1 more source

Amyloidogenesis promotes HSF1 activity enhancing cell survival during breast cancer metastatic colonization. [PDF]

Cell Stress Chaperones
Hockaden N, Leriger G, Wang J, Ray H, Chakrabarti S, Downing N, Desmond J, Williams D, Hollenhorst PC, Longmore G, Carpenter RL.   +10 more
europepmc   +1 more source

Excess of Interfering over Infectious Particles in Herpes Simplex Virus Passaged at High m.o.i. and their Effect on Single-cell Survival

, 1978
Claus H. Schröder, G. Urbaczka
openalex   +1 more source

Eradication of the intramedullary Ph1 positive cell live without accompanying improved survival in chronic myelogenous leukemia [PDF]

, 1978
Bernard R. Greenberg, Richard M. Ikeda, Jerry P. Lewis   +2 more
openalex   +1 more source

Loss of proton‐sensing GPR4 reduces tumor progression in mouse models of colon cancer

Molecular Oncology, EarlyView.
G protein‐coupled receptor 4 (GPR4) is a pH‐sensing receptor activated by acidic pH. GPR4 expression is increased in patients with inflammatory bowel disease who are at high risk of developing colorectal cancer. In mouse models, loss of GPR4 attenuated tumor progression. This correlated with increased IL2 and natural killer cell activity.
Leonie Perren, Moana Busch, Pedro A. Ruiz, Ermanno Malagola, Valeria Baumeler, Federica Foti, Adelina Gross, Tobias Grütter, Hendrik Edel, Cordelia Schuler, Kristina Handler, Glenn De Lange, Isabelle C. Arnold, Cheryl de Vallière, Klaus Seuwen, Martin Hausmann, Gerhard Rogler   +16 more
wiley   +1 more source

The transmembrane protein Syndecan is required for stem cell survival and maintenance of their nuclear properties. [PDF]

PLoS Genet
Eldridge-Thomas BL, Bohere JG, Roubinet C, Barthelemy A, Samuels TJ, Teixeira FK, Kolahgar G.   +6 more
europepmc   +1 more source

TRPM8 levels determine tumor vulnerability to channel agonists

Molecular Oncology, EarlyView.
TRPM8 is a Ca2+ permissive channel. Regardless of the amount of its transcript, high levels of TRPM8 protein mark different tumors, including prostate, breast, colorectal, and lung carcinomas. Targeting TRPM8 with channel agonists stimulates inward calcium currents followed by emptying of cytosolic Ca2+ stores in cancer cells.
Alessandro Alaimo, Francesco Giuseppe Carbone, Kristi Buzo, Nicole Annesi, Sacha Genovesi, Annalisa Lorenzato, Karen Widmann, Michela Libergoli, Elisa Marmocchi, Giovanni Bertalot, Alberto Brolese, Mauro Giulio Papotti, Luca Molinaro, Orazio Caffo, Mattia Barbareschi, Alberto Bardelli, Alessandro Romanel, Sabrina Arena, Andrea Lunardi   +18 more
wiley   +1 more source

PFKM-Mediated Glycolysis: A Pathway for ASIC1 to Enhance Cell Survival in the Acidic Microenvironment of Liver Cancer. [PDF]

Biomolecules
Wu X, Wang B, Hou Y, Fang Y, Jiang Y, Song Y, Liu Y, Jin C.   +7 more
europepmc   +1 more source

Long-Term Survival of Mouse Thymic Lymphoid Cells in Vitro: Effect of Human Serum [PDF]

, 1973
Keiko Ozato
openalex   +1 more source