Results 81 to 90 of about 14,964,075 (408)
MAM kinases: physiological roles, related diseases, and therapeutic perspectives—a systematic review
Cellular & Molecular Biology LettersMitochondria-associated membranes (MAMs) are tethering regions amid the membranes of the endoplasmic reticulum (ER) and mitochondria. They are a lipid raft-like structure occupied by various proteins that facilitates signal transduction between the two ...
A. Anjana Mohan, Priti Talwar
doaj +1 more source
Frontiers in Cell and Developmental Biology, 2021 Leucine-rich α2-glycoprotein-1 (LRG1) has been shown to impact both apoptosis and cell survival, pleiotropic effects similar to one of its known ligands, transforming growth factor-beta 1 (TGF-β1).
Ronald Jemmerson
doaj +1 more source
Comparative Survival Analysis of Deinococcus Radiodurans and the Haloarchaea Natrialba Magadii and Haloferax Volcanii, Exposed to Vacuum Ultraviolet Irradiation [PDF]
, 2011 The haloarchaea Natrialba magadii and Haloferax volcanii, as well as the radiation-resistant bacterium Deinococcus radiodurans, were exposed to vacuum-UV (V-UV) radiation at the Brazilian Synchrotron Light Laboratory (LNLS). Cell monolayers (containing 105 - 106 cells per sample) were prepared over polycarbonate filters and irradiated under high vacuum
arxiv +1 more source
Structural Derivative Model for Tissue Radiation Response [PDF]
, 2017 By means of a recently-proposed metric or structural derivative, called scale-q-derivative approach, we formulate differential equation that models the cell death by a radiation exposure in tumor treatments.
Sotolongo-Costa, Oscar +1 more
core +3 more sources
FEBS Letters, EarlyView.In lymphoid organs, antigen recognition and B cell receptor signaling rely on integrins and the cytoskeleton. Integrins act as mechanoreceptors, couple B cell receptor activation to cytoskeletal remodeling, and support immune synapse formation as well as antigen extraction.
Abhishek Pethe, Tanja Nicole Hartmann
wiley +1 more source
PTEN Regulates Glucose Transporter Recycling by Impairing SNX27 Retromer Assembly
Cell Reports, 2017 Summary: The tumor suppressor PTEN executes cellular functions predominantly through its phosphatase activity. Here we identified a phosphatase-independent role for PTEN during vesicular trafficking of the glucose transporter GLUT1.
Swapnil Rohidas Shinde +1 more
doaj
GM-CSF-Dependent Inflammatory Pathways
Frontiers in Immunology, 2019 Pre-clinical models and clinical trials demonstrate that targeting the action of the cytokine, granulocyte macrophage-colony stimulating factor (GM-CSF), can be efficacious in inflammation/autoimmunity reinforcing the importance of understanding how GM ...
John A. Hamilton, John A. Hamilton
doaj +1 more source
Cells, 2023 Cervical cancer is the most prevalent gynecological tumor among women worldwide. Although the incidence and mortality of cervical cancer have been declining thanks to the wide-scale implementation of cytological screening, it remains a major challenge in
Jun Zhang +5 more
doaj +1 more source
Parasite infection in a cell population with deaths [PDF]
arXiv, 2020 We introduce a general class of branching Markov processes for the modelling of a parasite infection in a cell population. Each cell contains a quantity of parasites which evolves as a diffusion with positive jumps. The growth rate, diffusive function and positive jump rate of this quantity of parasites depend on its current value. The division rate of
arxiv
Phase 1 Trial of Vaccination with Autologous Tumor Cells and Antisense Directed Against the Insulin Growth Factor Type 1 Receptor (IGF-1R AS ODN) in Patients with Recurrent Glioblastoma [PDF]
, 2018 Background: Extending a previous Phase I study, we report the results of a second Phase I autologous tumor cell vaccination trial for patients with recurrent glioblastomas (IND 14379-101, NCT01550523). Methods: Following surgery, subjects were treated by
Andrews MD, David W. +3 more
core +2 more sources