Results 231 to 240 of about 6,734,183 (300)

Redefining CHI3L1: Therapeutic Opportunities at the Crossroads of Immune Suppression and Disease Progression

open access: yesMedicinal Research Reviews, EarlyView.
ABSTRACT Chitinase‐3‐like‐1 (CHI3L1, also known as YKL‐40) has been recognized as a biomarker of inflammation and tissue remodeling and has now emerged as a pseudoenzymatic immune checkpoint. Recent structural, immunological, and translational studies redefine it as an active regulator of immune suppression rather than a passive disease marker. Despite
Kirti Upmanyu   +2 more
wiley   +1 more source

An Ulcerated Nodule on the Scalp

open access: yes
JEADV Clinical Practice, EarlyView.
Zainab Asghar   +2 more
wiley   +1 more source

The FGF/FGFR System in the Biology and Therapeutic Landscape of Pediatric CNS Tumors

open access: yesMedicinal Research Reviews, EarlyView.
ABSTRACT Central nervous system (CNS) tumors are the most common solid malignancies in children, comprising a highly heterogeneous group of neoplasms defined by distinct molecular alterations and clinical behaviors. Advances in molecular genetics have underscored the relevance of specific signaling pathways in driving pediatric tumorigenesis, among ...
Serena Filiberti   +6 more
wiley   +1 more source

ALDH, SOX and CD147 Εxpression in Oral Lichen Planus Compared to Oral Squamous Cell Carcinoma Epithelium: An Immunohistochemical Study. [PDF]

open access: yesCureus
Zisis V   +12 more
europepmc   +1 more source

Differential Transcriptome Analysis of Lung Squamous Cell Carcinoma Under Different RUNX3 Expression Patterns

open access: yesMedicine Advances, EarlyView.
RUNX3 status in lung squamous cell carcinoma (LUSC) is associated with subtle gene‐level differences but reveals exploratory pathway‐level patterns, including epithelial differentiation, extracellular matrix remodeling, and hypoxia‐related programs. These findings generate testable hypotheses for RUNX3's biological role in LUSC.
Weibin Liu   +10 more
wiley   +1 more source

2025 American Thyroid Association Management Guidelines for Adult Patients With Differentiated Thyroid Cancer: What's New for Surgeons?

open access: yesOtolaryngology–Head and Neck Surgery, EarlyView.
Abstract The American Thyroid Association (ATA) has published an update to the 2015 management guidelines for adult patients with thyroid nodules and differentiated thyroid cancer (DTC). This updated version focuses solely on the management of differentiated thyroid cancer, offering a comprehensive set of guidelines for all stakeholders in the care of ...
Chau Nguyen   +2 more
wiley   +1 more source

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