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Advancing neurofibromatosis research: a comparative review of animal models and their utility in dissecting the tumor microenvironment. [PDF]
Li AL, Chen YM.
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[Chromosomal telomere and neoplastic transformation and aging of cells].
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Cell surface protein and neoplastic transformation
Trends in Biochemical Sciences, 1976A major fibroblast glycoprotein that is diminished after malignant transformation has been isolated and partially characterized. Reconstitution experiments indicate that the glycoprotein helps maintain normal cell shape, adhesion, and contact inhibition of movement.
Kenneth M. Yamada, Ira Pastan
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The Neoplastic Transformation of SCID Cells by Radiation
Radiation Research, 1999Severe combined immunodeficiency (SCID) cells are hypersensitive to killing by ionizing radiation because of deregulation of DNA-dependent protein kinase (DNA-PK) and a concomitant deficiency in the repair of DNA double-strand breaks. The effect of this condition on the neoplastic transformation of SCID fibroblasts, designated SCID 3T1, has been ...
M, Lun +4 more
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Neoplastic Cell Transformation by Heavy Ions
Radiation Research, 1989We have studied the induction of morphological transformation by heavy ions. Golden hamster embryo cells were irradiated with 95 MeV 14N ions (530 keV/microns), 22 MeV 4He ions (36 keV/microns), and 22 MeV 4He ions with a 100-microns Al absorber (77 keV/microns) which were generated by a cyclotron at the Institute of Physical and Chemical Research in ...
M, Suzuki +4 more
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Neoplastic Cell Transformation by Heavy Charged Particles
Radiation Research Supplement, 1985With confluent cultures of the C3H10T1/2 mammalian cell line, we have investigated the effects of heavy-ion radiation on neoplastic cell transformation. Our quantitative data obtained with high-energy carbon, neon, silicon, argon, iron, and uranium particles show that RBE is both dose- and LET-dependent for malignant cell transformation.
T C, Yang +3 more
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Neoplastic transformation of primary tracheal epithelial cell cultures
Carcinogenesis, 1983Primary cultures of rat tracheal epithelial cells were treated with the chemical carcinogen N-methyl-N'-nitro-N-nitrosoguanidine (MNNG) to quantitatively study the early events during neoplastic transformation. Epithelial cells were dissociated from tracheas of specific-pathogen-free Fischer-344 rats and were plated on collagen-coated tissue culture ...
S B, Pai, V E, Steele, P, Nettesheim
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