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[Chromosomal telomere and neoplastic transformation and aging of cells].
Nihon Naika Gakkai zasshi. The Journal of the Japanese Society of Internal Medicine, 1997 openaire +1 more source
Radiation-induced neoplastic transformation of human cells. [PDF]
Scanning microscopy, 1993 Ionizing radiation can induce cancers in humans and animals and can cause in vitro neoplastic transformation of various rodent cell systems. However, numerous attempts to achieve neoplastic transformation of human cells by radiation have generally proven unsuccessful.
Rhim, J. S. +4 more
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Some Characteristics of Neoplastic Cell Transformation in Transgenic Mice
1996The role of the expression of different cellular genes and viral oncogenes in malignant cell transformation is discussed. We pay special attention to the role of the genes for growth factors and their receptors and homeobox genes in oncogenesis. Based on both the literature and our own data, specific features of tumors developed in transgenic mice are ...
I N, Shvemberger, A N, Ermilov
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The Pathway of Neoplastic Transformation of Human Breast Epithelial Cells
Radiation Research, 2001The morphological analysis of breast cancer development indicates this to be a multistep process that progressively evolves from ductal hyperplasia and atypical ductal hyperplasia, which represent the initial stages of neoplastic growth, to carcinoma in situ, invasive carcinoma, and ultimately metastasis, as has been documented for a number of other ...
J, Russo, I H, Russo
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Infrared parameters in the characterization of the neoplastic cell transformation
Microchemical Journal, 1992Abstract In this paper we report the results on the characterization of neoplastic cells by means of FT-IR spectroscopy. Spectral differences have been found in examining normal and leukemic lymphocytes. Through analyzing also nuclei extracted from normal and leukemic lymphocytes an increase of DNA with respect to proteic components was observed in ...
Enzo Benedetti +7 more
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Epigenetic Transformation by RNA from Human Neoplastic Cells
Oncology, 2009The study of biologic properties of nucleic acids from either normal or malignant cells transcends the search for subviral infectivity. The differing results obtained in studying the behavior of nucleic acids from human malignant cells on primary cultures are critically reviewed in the light of the methodology involved.
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In Which Cells Does Neoplastic Transformation Occur in Myelomatosis?
1992Myelomatosis is strictly a neoplasm of plasma cells in bone marrow. It does not involve other sites of antibody production; thus, even when the monoclonal protein produced by the neoplastic clone is IgA1 or IgA2 the neoplastic cells are not found in the lamina propria of the gut (Leonard et al 1979).
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[Differentiation and the neoplastic transformation of normal cells].
Tsitologiia, 1984It is suggested that blastomogenic factors can be considered as the means isolating normal cells from each other. Carcinogenic substances caused cell functions to disturb, to inhibit or to intensify the synthesis of specific substances, to change the cell surface disrupted contacts of interactions between cells, pressing cells to become on the way of ...
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Neoplastic transformation of human cells in vitro.
Critical reviews in oncogenesis, 1993Efforts to investigate the progression of events that lead normal human cells in culture to become neoplastic in response to carcinogenic agents have been aided by the development of the suitable in vitro model systems. For initial human cell transformation studies, a flat, nontumorigenic clonal line, originally derived from a human osteosarcoma (HOS),
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