Results 281 to 290 of about 776,463 (349)

Oncogenic Mechanisms of Kaposi's Sarcoma-Associated Herpesvirus on Cell Metabolism and Cell Transformation. [PDF]

J Med Virol
Wan Q, Tucker AJ, Zhao J.
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Adenovirus E1B-55K regulates p53-dependent and -independent gene expression during infection. [PDF]

PLoS Pathog
Seddar L, von Stromberg K, Bertzbach LD, Grundhoff A, Dobner T, Ip WH.   +5 more
europepmc   +1 more source

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Cell-Driven Viral Transformation

1985
Since the advent of hybridoma technology, one of the most provocative applications for monoclonal antibodies has been immunotherapy. Early reports of experiments performed in mice suggested that monoclonal antibody therapy was beneficial against murine T-cell lymphoma (Bernstein et al., 1980) and that it might be useful to deliver potent toxins to ...
Anthony W. Siadak, Mark E. Lostrom
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Proteolytic Enzymes, Cell Surface Changes, and Viral Transformation

Advances in Cancer Research, 1976
Publisher Summary This chapter reviews the evidence for and against the view that proteolysis plays a role in determining some of the phenotypic characteristics of virus-transformed cells. It discusses some aspects of the structure of the cellular membrane surface because one possible mechanism by which proteases might alter cell properties is via ...
R, Robin, I N, Chou, P H, Black
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Cell Transformation By The Viral SRC Oncogene

Annual Review of Cell and Developmental Biology, 1987
Richard Jove, Hidesaburo Hanafusa
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Viral Transformation of Epithelial Cells

2012
Approximately 18% of human cancers have a viral etiology and the majority of these involve transformation of epithelial cells. Viral proteins transform epithelia by inducing alterations in the normal cell growth and differentiation pathways through the targeting of host proteins.
Jennifer A, Regan, Laimonis A, Laimins
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Cell Transformation by the Viral src Oncogene

Annual Review of Cell Biology, 1987
PERSPECTIVES AND SUMMARy . .... . . ... ......... . . . . . . . . .. . . . . 31 OVERVIEW OF CELL TRANSFORMATION . .. ..... . ......... . . .. ". . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 32 ORIGIN OF VIRAL src . ..... ..... . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .....
R, Jove, H, Hanafusa
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The viral genome in transformed cells

Proceedings of the Royal Society of London. Series B. Biological Sciences, 1971
Polyoma and SV 40-transformed cells carry multiple copies of the entire genome in their chromosomes; the viral DNA sequences appear to be covalently integrated into the host cell’s DNA but it is not known whether they are clustered in a reiterated tandem sequence or whether they are distributed singly or in clusters throughout the cell’s chromosomes ...
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Viral Transformation of Monkey Kidney Cell Cultures

Nature, 1967
Simian tumour virus SV40 induces transformation of primary cultures of cercopithecus monkey kidney cells. The cells become highly vacuolated, complement fixing viral antigen is formed and the cells become resistant to the cytopathic effects of the virus. It is probable that a persistent association develops between the cells and the virus genome.
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Epidermal Growth Factors Enhances Viral Transformation of Granulosa Cells

Science, 1981
Kirsten sarcoma virus produced a low incidence of transient morphological transformation in primary cultures of rat ovarian granulosa cells. In the presence of epidermal growth factor, the incidence of transient transformation increased severalfold and two continuous cell lines were established.
J, Harrison, N, Auersperg
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