The promoters of human cell cycle genes integrate signals from two tumor suppressive pathways during cellular transformation [PDF]
, 2005 Deciphering regulatory events that drive malignant transformation represents a major challenge for systems biology. Here we analyzed genome-wide transcription profiling of an in-vitro transformation process.
Assif Yitzhaky +17 more
core +3 more sources
The role of miR-200a in mammalian epithelial cell transformation.
Carcinogenesis, 2015 Cancer is a multistep disease that begins with malignant cell transformation and frequently culminates in metastasis. MicroRNAs (miRNAs) are small regulatory 21-25 nt RNA molecules and are frequently deregulated in cancer. miR-200a is a member of the miR-
Lindsey E. Becker +3 more
semanticscholar +1 more source
Identification of senescence and death in Emiliania huxleyi and Thalassiosira pseudonana: Cell staining, chlorophyll alterations, and dimethylsulfoniopropionate (DMSP) metabolism [PDF]
, 2012 We measured membrane permeability, hydrolytic enzyme, and caspase-like activities using fluorescent cell stains to document changes caused by nutrient exhaustion in the coccolithophore Emiliania huxleyi and the diatom Thalassiosira pseudonana, during ...
Airs, Ruth L. +6 more
core +1 more source
Low-frequency Selection Switch based Cell-to-Cell Battery Voltage Equalizer with Reduced Switch Count [PDF]
, 2020 A selection switch based cell-to-cell voltage equalizer requires only one dual-port dc-dc converter shared by all the cells. A cell-to-cell voltage equalizer is proposed that utilizes a capacitively level-shifted Cuk converter and low-frequency cell selection switches.
arxiv +1 more source
Oncogenic fusion protein BCR-FGFR1 requires the breakpoint cluster region-mediated oligomerization and chaperonin Hsp90 for activation. [PDF]
, 2020 Mutation and translocation of fibroblast growth factor receptors often lead to aberrant signaling and cancer. This work focuses on the t(8;22)(p11;q11) chromosomal translocation which creates the breakpoint cluster region (BCR) fibroblast growth factor ...
Bisom-Rapp, Ezra W +4 more
core +2 more sources
Fourier transform infrared cell for surface studies at controlled temperatures and in controlled atmospheres with time resolution and spatial resolution [PDF]
, 1996 A new micro-Fourier transform infrared cell has been constructed and evaluated using (i) the transformation of aurichalcite crystals at 298-475 K, (ii) the adsorption/desorption of pyridine on a Cu2O/ZnO junction, and (iii) the adsorption of CO on Pt ...
Greek B. F., P. A. Sermon, V. A. Self
core +1 more source
Analysis of the clinical relevance of histological classification of benign epithelial salivary gland tumours [PDF]
, 2019 IntroductionA vast increase in knowledge of numerous aspects of malignant salivary gland tumours has emerged during the last decade and, forseveral reasons, thishas not been the case in benign epithelial salivary gland tumours.
Andreasen, Simon +10 more
core +4 more sources
BK Virus in Cancer Development
Current Issues in Pharmacy and Medical Sciences, 2018 Polyomavirus (PyV) was discovered by accident in 1950 in the course of describing an infectious factor causing multiple tumours in rodents. The term is derived from two Greek words: poly (many) and oma (tumour).
Pasternak Justyna +2 more
doaj +1 more source
Dysplastic transformation of plasma cell myeloma
Journal of Applied Hematology, 2022 Rare cases of plasma cell myeloma with morphological variants have been reported. Here we report a case of a plasma cell myeloma with a very unusual presentation diagnosed based on flow cytometry, immunohistochemistry, and cytogenetic studies.
Laila Alsuhaibani, Tarek Owaidah
doaj +1 more source
Rab11 regulates E-cadherin expression and induces cell transformation in colorectal carcinoma
BMC Cancer, 2014 BackgroundIn the process of epithelial mesenchymal transition EMT, the disassembly of junctional adhesion complexes such as E-cadherin is a remarkable sign during changes in cell morphology and polarity.
Yuan‐Chiang Chung +6 more
semanticscholar +1 more source