Results 1 to 10 of about 2,227,755 (198)

Simvastatin inhibits POVPC-mediated induction of endothelial-to-mesenchymal cell transition [PDF]

open access: yesJournal of Lipid Research, 2021
Endothelial-to-mesenchymal transition (EndMT), the process by which an endothelial cell (EC) undergoes a series of molecular events that result in a mesenchymal cell phenotype, plays an important role in atherosclerosis.
Yan Li   +13 more
doaj   +2 more sources

Single cell transcriptomics of human epidermis identifies basal stem cell transition states [PDF]

open access: yesNature Communications, 2020
The mechanisms regulating stem cells to give rise to human interfollicular epidermis are unclear. Here, the authors use single cell RNA sequencing to identify heterogeneity within the human neonatal interfollicular epidermis and distinct spatial ...
Shuxiong Wang   +11 more
doaj   +2 more sources

Transition state characteristics during cell differentiation.

open access: yesPLoS Computational Biology, 2018
Models describing the process of stem-cell differentiation are plentiful, and may offer insights into the underlying mechanisms and experimentally observed behaviour.
Rowan D Brackston   +2 more
doaj   +6 more sources

Familial Transitional Cell Carcinoma [PDF]

open access: yesThe Journal of Urology, 1996
Bladder cancer is a common malignancy, and a frequent cause of urological consultation and surgical intervention. Except for smoking and certain occupational exposures, the etiology of bladder cancer is largely unknown. Although the majority of patients with bladder cancer do not have a family history of transitional cell carcinoma of the urinary tract,
Kiemeney, L.A.L.M., Schoenberg, M.P.
openaire   +4 more sources

Plant cell cycle transitions [PDF]

open access: yesCurrent Opinion in Plant Biology, 2003
Three decades have passed since the first recognition of restriction checkpoints in the plant cell cycle. Although many core cell cycle genes have been cloned, the mechanisms that control the G1-->S and G2-->M transitions in plants have only recently started to be understood.
Lieven, De Veylder   +2 more
openaire   +2 more sources

Canine Transitional Cell Carcinoma [PDF]

open access: yesJournal of Veterinary Internal Medicine, 2003
Transitional cell carcinoma (TCC) of the urinary bladder, the most common malignancy of the urinary tract in dogs, is challenging to both diagnose and treat effectively. The prevalence of this disease may be increasing. The etiology of canine TCC is likely multifactorial. Epidemiological studies of TCC in the dog have revealed a number of risk factors,
Anthony J, Mutsaers   +2 more
openaire   +2 more sources

Zfp281 Inhibits the Pluripotent-to-Totipotent State Transition in Mouse Embryonic Stem Cells

open access: yesFrontiers in Cell and Developmental Biology, 2022
The cell-fate transition between pluripotent and totipotent states determines embryonic development and the first cell-lineage segregation. However, limited by the scarcity of totipotent embryos, regulators on this transition remain largely elusive.
Xinpeng Wen   +7 more
doaj   +1 more source

Knockdown of TPT1-AS1 inhibits cell proliferation, cell cycle G1/S transition, and epithelial–mesenchymal transition in gastric cancer

open access: yesBiomolecules & Biomedicine, 2021
Long non-coding RNAs are considered to be critical regulators of tumor progression. Tumor protein translationally controlled 1 antisense RNA 1 (TPT1-AS1) was shown to have an oncogenic role in cervical and ovarian cancer.
Jun Tang   +6 more
doaj   +1 more source

Microbiome and morbid obesity increase pathogenic stimulus diversity

open access: yes4 open, 2019
The microbiome, the relationship between environmental factors, a high-fat diet, morbid obesity, and host response have been associated with cancer, only a small fraction of which (
Brücher Björn L.D.M., Jamall Ijaz S.
doaj   +1 more source

Precancerous niche (PCN), a product of fibrosis with remodeling by incessant chronic inflammation

open access: yes4 open, 2019
Fibroblasts are actively involved in the creation of the stroma and the extracellular matrix which are important for cell adhesion, cell–cell communication, and tissue metabolism.
Brücher Björn L.D.M., Jamall Ijaz S.
doaj   +1 more source

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