Results 1 to 10 of about 2,227,755 (198)
Simvastatin inhibits POVPC-mediated induction of endothelial-to-mesenchymal cell transition [PDF]
Endothelial-to-mesenchymal transition (EndMT), the process by which an endothelial cell (EC) undergoes a series of molecular events that result in a mesenchymal cell phenotype, plays an important role in atherosclerosis.
Yan Li +13 more
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Single cell transcriptomics of human epidermis identifies basal stem cell transition states [PDF]
The mechanisms regulating stem cells to give rise to human interfollicular epidermis are unclear. Here, the authors use single cell RNA sequencing to identify heterogeneity within the human neonatal interfollicular epidermis and distinct spatial ...
Shuxiong Wang +11 more
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Transition state characteristics during cell differentiation.
Models describing the process of stem-cell differentiation are plentiful, and may offer insights into the underlying mechanisms and experimentally observed behaviour.
Rowan D Brackston +2 more
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Familial Transitional Cell Carcinoma [PDF]
Bladder cancer is a common malignancy, and a frequent cause of urological consultation and surgical intervention. Except for smoking and certain occupational exposures, the etiology of bladder cancer is largely unknown. Although the majority of patients with bladder cancer do not have a family history of transitional cell carcinoma of the urinary tract,
Kiemeney, L.A.L.M., Schoenberg, M.P.
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Plant cell cycle transitions [PDF]
Three decades have passed since the first recognition of restriction checkpoints in the plant cell cycle. Although many core cell cycle genes have been cloned, the mechanisms that control the G1-->S and G2-->M transitions in plants have only recently started to be understood.
Lieven, De Veylder +2 more
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Canine Transitional Cell Carcinoma [PDF]
Transitional cell carcinoma (TCC) of the urinary bladder, the most common malignancy of the urinary tract in dogs, is challenging to both diagnose and treat effectively. The prevalence of this disease may be increasing. The etiology of canine TCC is likely multifactorial. Epidemiological studies of TCC in the dog have revealed a number of risk factors,
Anthony J, Mutsaers +2 more
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Zfp281 Inhibits the Pluripotent-to-Totipotent State Transition in Mouse Embryonic Stem Cells
The cell-fate transition between pluripotent and totipotent states determines embryonic development and the first cell-lineage segregation. However, limited by the scarcity of totipotent embryos, regulators on this transition remain largely elusive.
Xinpeng Wen +7 more
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Long non-coding RNAs are considered to be critical regulators of tumor progression. Tumor protein translationally controlled 1 antisense RNA 1 (TPT1-AS1) was shown to have an oncogenic role in cervical and ovarian cancer.
Jun Tang +6 more
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Microbiome and morbid obesity increase pathogenic stimulus diversity
The microbiome, the relationship between environmental factors, a high-fat diet, morbid obesity, and host response have been associated with cancer, only a small fraction of which (
Brücher Björn L.D.M., Jamall Ijaz S.
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Precancerous niche (PCN), a product of fibrosis with remodeling by incessant chronic inflammation
Fibroblasts are actively involved in the creation of the stroma and the extracellular matrix which are important for cell adhesion, cell–cell communication, and tissue metabolism.
Brücher Björn L.D.M., Jamall Ijaz S.
doaj +1 more source

