Results 141 to 150 of about 9,650,343 (306)

The Fetal-to-Adult Hematopoietic Stem Cell Transition and its Role in Childhood Hematopoietic Malignancies. [PDF]

Stem Cell Rev Rep, 2021
Mack R, Zhang L, Breslin Sj P, Zhang J.
europepmc   +1 more source

The ubiquitin system in normal and infected germinal center B cells

FEBS Letters, EarlyView.
The ubiquitin system plays a central role in germinal center (GC) B cells, influencing differentiation to long‐lived memory B cells. Oncogenic gammaherpesviruses gain access to memory B cells by establishing latency in GC B cells. Mapping ubiquitin mechanisms in normal and infected GC B cells will define specific molecular circuits in B cells germane ...
Destiny Davis, Lesly Mejia, Emily K Moser   +2 more
wiley   +1 more source

Epithelial mesenchymal transition traits in human breast cancer cell lines

, 2008
Epithelial mesenchymal transition (EMT) has long been associated with breast cancer cell invasiveness and evidence of EMT processes in clinical samples is growing rapidly.
Widodo, E., Waltham, M., Hugo, Honor J., E. Widodo, Thompson, E.W., Neve, R.M., H. Hugo, Blick, T., E. W. Thompson, T. Blick, M. E. Lenburg, Lenburg, M.E., M. Waltham, R. M. Neve   +13 more
core   +1 more source

Impaired AT2 to AT1 cell transition in PM2.5-induced mouse model of chronic obstructive pulmonary disease. [PDF]

Respir Res, 2022
Yu H, Lin Y, Zhong Y, Guo X, Lin Y, Yang S, Liu J, Xie X, Sun Y, Wang D, Li B, Ran P, Dai J.   +12 more
europepmc   +1 more source

Metastatic niche shaped by host factors influences disseminated cancer cell fate

FEBS Letters, EarlyView.
Metastasis is shaped not only by cancer cells but also by the environments they encounter. This review explores how factors such as aging, diet, the microbiome, lifestyle, and environmental exposures remodel organ‐specific niches in the lung, liver, bone, and brain, influencing where metastatic cells survive, remain dormant, or grow, and ultimately ...
Gwennan Delyth Ward, Álvaro Ruiz‐Tabas, Patricia Altea‐Manzano   +2 more
wiley   +1 more source

5-Alpha reductase inhibitors induce a prostate luminal to club cell transition in human benign prostatic hyperplasia. [PDF]

J Pathol, 2022
Joseph DB, Henry GH, Malewska A, Reese JC, Mauck RJ, Gahan JC, Hutchinson RC, Mohler JL, Roehrborn CG, Strand DW.   +9 more
europepmc   +1 more source

Smaller is better: nanobodies meet NMR

FEBS Letters, EarlyView.
Nanobodies are single‐domain antigen‐binding fragments derived from camelid heavy chain antibodies. Their small size, high stability, and exceptional specificity make nanobodies uniquely useful probes for NMR studies of protein dynamics, transient conformational states, and protein–protein interactions.
Oleg Y. Dmitriev
wiley   +1 more source

TGF-β and the Smad signaling pathway support transcriptomic reprogramming during epithelial-mesenchymal cell transition

, 2005
Epithelial-mesenchymal transition (EMT) contributes to normal tissue patterning and carcinoma invasiveness. We show that transforming growth factor (TGF)-beta/activin members, but not bone morphogenetic protein (BMP) members, can induce EMT in normal ...
Kowanetz, Marcin,, Valcourt, Ulrich,, Niimi, Hideki,, Heldin, Carl-Henrik,, Moustakas, Aristidis,   +4 more
core   +1 more source

Invisible but not inaccessible—Revealing transient oligomers formed by intrinsically disordered proteins with solution NMR and complementary methods

FEBS Letters, EarlyView.
Transient oligomers formed by intrinsically disordered proteins may be ‘invisible’ to direct detection yet remain accessible to solution NMR through equilibrium‐exchange measurements and pressure‐jump experiments. Complementary methods report on mass, stoichiometry, selected distance distributions, morphology, and internal packing.
Martin D. Gelenter, Ad Bax
wiley   +1 more source

A Transition Odyssey Technical Assistance about Transition and the Rehabilitation Act (NCSET Capacity Building Institute)

, 2001
A transcript of a Capacity Building Institute (CBI) that was sponsored by NCSET and PACER Center. It included nationally recognized speakers on transition planning and discussion groups focusing on parent involvement in postsecondary education ...
National Center on Secondary Education and Transition
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