Results 51 to 60 of about 103,075 (235)

Participation of Candida albicans transcription factor RLM1 in cell wall biogenesis and virulence. [PDF]

PLoS ONE, 2014
Candida albicans cell wall is important for growth and interaction with the environment. RLM1 is one of the putative transcription factors involved in the cell wall integrity pathway, which plays an important role in the maintenance of the cell wall ...
Yolanda Delgado-Silva, Catarina Vaz, Joana Carvalho-Pereira, Catarina Carneiro, Eugénia Nogueira, Alexandra Correia, Laura Carreto, Sónia Silva, Augusto Faustino, Célia Pais, Rui Oliveira, Paula Sampaio   +11 more
doaj   +1 more source

Functional Characterization of Two Cell Wall Integrity Pathway Components of the MAPK Cascade inPhomopsis longicolla

Molecular Plant-Microbe Interactions®, 2023
The pathogenic fungus Phomopsis longicolla causes numerous plant diseases, such as Phomopsis seed decay, pod and stem blight, and stem canker, which seriously affect the yield and quality of soybean production worldwide. Because of a lack of technology for efficient manipulation of genes for functional genomics, understanding of P.
Chen Zhang, Haifeng Zhang, Xiaobo Zheng, Yuanchao Wang, Wenwu Ye   +4 more
openaire   +3 more sources

The importance of connections between the cell wall integrity pathway and the unfolded protein response in filamentous fungi [PDF]

Briefings in Functional Genomics, 2014
In the external environment, or within a host organism, filamentous fungi experience sudden changes in nutrient availability, osmolality, pH, temperature and the exposure to toxic compounds. The fungal cell wall represents the first line of defense, while also performing essential roles in morphology, development and virulence.
Iran, Malavazi, Gustavo Henrique, Goldman, Neil Andrew, Brown   +2 more
openaire   +2 more sources

Genome‐wide analysis of gene expression regulated by the yeast cell wall integrity signalling pathway [PDF]

Molecular Microbiology, 1999
The cell integrity pathway of Saccharomyces cerevisiae monitors cell wall remodelling during growth and differentiation. Additionally, this pathway responds to environmental stresses that challenge the integrity of the cell wall. We conducted a genome‐wide survey of genes whose expression was altered in response to activation of Mpk1/Slt2, the MAP ...
U S, Jung, D E, Levin
openaire   +2 more sources

Fission yeast cell wall biosynthesis and cell integrity signalling

The Cell Surface, 2018
The cell wall is a structure external to the plasma membrane that is essential for the survival of the fungi. This polysaccharidic structure confers resistance to the cell internal turgor pressure and protection against mechanical injury. The fungal wall
Pilar Pérez, Juan C.G. Cortés, Jose Cansado, Juan C. Ribas   +3 more
doaj   +1 more source

Cdc48 and cofactors Npl4-Ufd1 are important for G1 progression during heat stress by maintaining cell wall integrity in Saccharomyces cerevisiae. [PDF]

PLoS ONE, 2011
The ubiquitin-selective chaperone Cdc48, a member of the AAA (ATPase Associated with various cellular Activities) ATPase superfamily, is involved in many processes, including endoplasmic reticulum-associated degradation (ERAD), ubiquitin- and proteasome ...
Meng-Ti Hsieh, Rey-Huei Chen
doaj   +1 more source

Microbiome−host proteostasis crosstalk—An emerging perspective on mechanisms and interventions toward healthy longevity

FEBS Letters, EarlyView.
Proteostasis and the gut microbiota play a key role in shaping host physiology. Microbiota‐derived metabolites, vitamins, and RNA modulate host proteostasis. Findings from model systems, including C. elegans, indicate microbes can either stabilize or disrupt host proteostasis.
Abhishek Anil Dubey, Maria Ermolaeva
wiley   +1 more source

Atkinesin-13A modulates cell-wall synthesis and cell expansion in Arabidopsis thaliana via the THESEUS1 pathway. [PDF]

PLoS Genetics, 2014
Growth of plant organs relies on cell proliferation and expansion. While an increasingly detailed picture about the control of cell proliferation is emerging, our knowledge about the control of cell expansion remains more limited.
Ushio Fujikura, Lore Elsaesser, Holger Breuninger, Clara Sánchez-Rodríguez, Alexander Ivakov, Thomas Laux, Kim Findlay, Staffan Persson, Michael Lenhard   +8 more
doaj   +1 more source

From mice to humans—divergent strategies for intestinal homeostasis and regeneration

FEBS Letters, EarlyView.
Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa, Shinya Sugimoto, Toshiro Sato   +2 more
wiley   +1 more source

Identification and Functional Testing of Novel Interacting Protein Partners for the Stress Sensors Wsc1p and Mid2p of Saccharomyces cerevisiae

G3: Genes, Genomes, Genetics, 2019
Wsc1p and Mid2p are transmembrane signaling proteins of cell wall stress in the budding yeast Saccharomyces cerevisiae. When an environmental stress compromises cell wall integrity, they activate a cell response through the Cell Wall Integrity (CWI ...
Ednalise Santiago-Cartagena, Sahily González-Crespo, Vladimir Vélez, Nelson Martínez, Jamie Snider, Matthew Jessulat, Hiroyuki Aoki, Zoran Minic, Pearl Akamine, Inoushka Mejías, Luis M. Pérez, Brian C. Rymond, Mohan Babu, Igor Stagljar, José R. Rodríguez-Medina   +14 more
doaj   +1 more source