Results 11 to 20 of about 9,990 (205)

Automated muscle histopathology analysis using CellProfiler [PDF]

open access: yesSkeletal Muscle, 2018
Background Histological assessment of skeletal muscle sections is important for the research of muscle physiology and diseases. Quantifiable measures of skeletal muscle often include mean fiber diameter, fiber size distribution, and centrally nucleated ...
Yeh Siang Lau   +3 more
doaj   +4 more sources

CellProfiler 4: improvements in speed, utility and usability [PDF]

open access: yesBMC Bioinformatics, 2021
Background Imaging data contains a substantial amount of information which can be difficult to evaluate by eye. With the expansion of high throughput microscopy methodologies producing increasingly large datasets, automated and objective analysis of the ...
David R. Stirling   +5 more
doaj   +5 more sources

CellProfiler plugins – An easy image analysis platform integration for containers and Python tools [PDF]

open access: yesJournal of Microscopy, 2023
AbstractCellProfiler is a widely used software for creating reproducible, reusable image analysis workflows without needing to code. In addition to the >90 modules that make up the main CellProfiler program, CellProfiler has a plugins system that allows for the creation of new modules which integrate with other Python tools or tools that are ...
Erin Weisbart   +9 more
openaire   +5 more sources

CellProfiler™: free, versatile software for automated biological image analysis [PDF]

open access: yesBioTechniques, 2007
Careful visual examination of biological samples is quite powerful, but many visual analysis tasks done in the laboratory are repetitive, tedious, and subjective.
Michael R. Lamprecht   +2 more
doaj   +3 more sources

CellProfiler: image analysis software for identifying and quantifying cell phenotypes [PDF]

open access: yesGenome Biology, 2006
AbstractBiologists can now prepare and image thousands of samples per day using automation, enabling chemical screens and functional genomics (for example, using RNA interference). Here we describe the first free, open-source system designed for flexible, high-throughput cell image analysis, CellProfiler.
Carpenter, Anne E.   +11 more
openaire   +6 more sources

An image analysis protocol using CellProfiler for automated quantification of post-ischemic cardiac parameters

open access: yesSTAR Protocols, 2022
Summary: Quantitative assessment of post-ischemic cardiac remodeling is often hampered by tissue complexity and structural heterogeneity of the scar.
Alexander O. Ward   +4 more
doaj   +3 more sources

Automated lipid droplet quantification system for phenotypic analysis of adipocytes using CellProfiler

open access: yesToxicology Mechanisms and Methods, 2020
Adipogenic differentiation is the process by which preadipocytes become mature adipocytes, cells that store energy and regulate metabolic homeostasis. During differentiation, neutral lipids that accumulate in adipocytes can be detected using stains and used as an index of cell differentiation.
Victoria Adomshick   +2 more
openaire   +4 more sources

ImageJ and CellProfiler: Complements in Open‐Source Bioimage Analysis

open access: yesCurrent Protocols, 2021
AbstractImageJ and CellProfiler have long been leading open‐source platforms in the field of bioimage analysis. ImageJ's traditional strength is in single‐image processing and investigation, while CellProfiler is designed for building large‐scale, modular analysis pipelines. Although many image analysis problems can be well solved with one or the other,
Dobson ETA   +5 more
openaire   +4 more sources

Automated segmentation and quantitative analysis of organelle morphology, localization and content using CellProfiler.

open access: yesPLoS ONE, 2023
One of the most used and versatile methods to study number, dimensions, content and localization of secretory organelles is confocal microscopy analysis.
Sebastiaan N J Laan   +5 more
doaj   +4 more sources

CellProfiler Analyst: data exploration and analysis software for complex image-based screens [PDF]

open access: yesBMC Bioinformatics, 2008
Background Image-based screens can produce hundreds of measured features for each of hundreds of millions of individual cells in a single experiment. Results Here, we describe CellProfiler Analyst, open-source software for the interactive exploration and
Papallo Adam   +7 more
doaj   +6 more sources

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