Results 31 to 40 of about 9,990 (205)
CP2Image: Generating High-Quality Single-Cell Images Using CellProfiler Representations [PDF]
, 2023 Single-cell high-throughput microscopy images contain key biological information underlying normal and pathological cellular processes. Image-based analysis and profiling are powerful and promising for extracting this information but are made difficult ...
Cutiongco, Marie F.A. +3 more
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Image-based cell profiling enhancement via data cleaning methods.
PLoS ONE, 2022 With the advent of high-throughput assays, a large number of biological experiments can be carried out. Image-based assays are among the most accessible and inexpensive technologies for this purpose.
Arghavan Rezvani +2 more
doaj +1 more source
A novel method for automated assessment of megakaryocyte differentiation and proplatelet formation
Platelets, 2018 Transfusion of platelet concentrates represents an important treatment for various bleeding complications. However, the short half-life and frequent contaminations with bacteria restrict the availability of platelet concentrates and raise a clear demand ...
M. Salzmann +9 more
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Open Research Europe, 2022 Microscopy has revolutionised our view on biology and has been vital for many discoveries since its invention around 200 years ago. Recent developments in cell biology have led to a strong interest in generating spheroids and organoids ...
Fredrik Wieland +5 more
doaj +1 more source
Head-to-head comparison of three experimental methods of quantifying competitive fitness in C. elegans. [PDF]
PLoS ONE, 2018 Organismal fitness is relevant in many contexts in biology. The most meaningful experimental measure of fitness is competitive fitness, when two or more entities (e.g., genotypes) are allowed to compete directly.
Timothy A Crombie +4 more
doaj +1 more source
An open access, machine learning pipeline for high-throughput quantification of cell morphology
STAR Protocols, 2023 Summary: Cell morphology is influenced by many factors and can be used as a phenotypic marker. Here we describe a machine-learning-based protocol for high-throughput morphological measurement of human fibroblasts using a standard fluorescence microscope ...
Emma M. Welter +2 more
doaj +1 more source
QuickCount®: a novel automated software for rapid cell detection and quantification
BioTechniques, 2018 We describe a novel automated cell detection and counting software, QuickCount® (QC), designed for rapid quantification of cells. The Bland–Altman plot and intraclass correlation coefficient (ICC) analyses demonstrated strong agreement between cell ...
Kai Hung Tiong +8 more
doaj +1 more source
STAR Protocols, 2022 Summary: Nucleocytoplasmic transport (NCT) plays critical roles in maintaining cellular homeostasis. Here, we present a protocol to measure NCT for both transcript and protein cargos in cultured cells.
Haochen Cui +5 more
doaj +1 more source
BioTechniques, 2023 Single cell cytometry has demonstrated plausible immuno-heterogeneity of mesenchymal stem cells (MSCs) owing to their multivariate stromal origin. To contribute successfully to next-generation stem cell therapeutics, a deeper understanding of their ...
Ayona Gupta +3 more
doaj +1 more source
CellProfiler: Open-Source Software to Automatically Quantify Images [PDF]
Microscopy Today, 2008 Abstract Researchers often examine samples by eye on the microscope — qualitatively scoring each sample for a particular feature of interest. This approach, while suitable for many experiments, sacrifices quantitative results and a permanent record of the experiment.
Martha S Vokes, Anne E Carpenter
openaire +1 more source