Results 111 to 120 of about 2,209,887 (300)

Hijacking emergency granulopoiesis: Neutrophil ontogeny and reprogramming in cancer

Molecular Oncology, EarlyView.
Neutrophils are highly plastic innate immune cells; their functions in cancer extend beyond the tumour microenvironment. This Review summarises current understanding of neutrophil maturation and heterogeneity and highlights tumour‐induced granulopoiesis as a systemic programme that expands immature, immunosuppressive neutrophils via tumour‐derived ...
Gabriela Marinescu, Yi Feng
wiley   +1 more source

The effect of IL-1β on cellular invasion (a) and adhesion (b).

, 2022
a, In melanoma cells, cellular invasion was undetectable. b, Cellular adhesion of IL-1β, UK356618, and UK356618+ IL-1β-treated cells showed no significant difference compared to control.
Tomohiro Nakayama (30894), Hiroshi Sugiya (412101), Rei Nakano (820735), Shinichi Namba (3350288), Taku Kitanaka (3350276), Nanako Kitanaka (3350285), Masumi Nakano (11648962), Mana Sugimura (10098514), Manami Kuji (10098511), Atsuto Naruke (11648956), Naoya Yachiku (10098508), Junichi Nunomura (11648959), Yoko Suwabe (9468965)   +12 more
core   +1 more source

Epithelial cell chirality emerges through the dynamic concentric pattern of actomyosin cytoskeleton

eLife
The chirality of tissues and organs is essential for their proper function and development. Tissue-level chirality derives from the chirality of individual cells that comprise the tissue, and cellular chirality is considered to emerge through the ...
Takaki Yamamoto, Tomoki Ishibashi, Yuko Mimori-Kiyosue, Sylvain Hiver, Naoko Tokushige, Mitsusuke Tarama, Masatoshi Takeichi, Tatsuo Shibata   +7 more
doaj   +1 more source

Metastasis on pause: How dormant tumor cells stay hidden within the tumor microenvironment and evade immune surveillance

Molecular Oncology, EarlyView.
Dormant cancer cells can hide in distant organs for years, evading treatment and the immune system. This review highlights how signals from the surrounding tissue and immune environment keep these cells inactive or trigger their reawakening. Understanding these mechanisms may help develop therapies to eliminate or control dormant cells and prevent ...
Kanishka Tiwary, Jose Javier Bravo‐Cordero   +1 more
wiley   +1 more source

Cellular adhesion on PEG-DA hydrogels.

, 2018
Cells adhered to PEG-DMA hydrogels with RGD peptides (RGD++) on days 1, 6, 11, and 15. Cells appeared more rounded and sparse on hydrogels without RGD (RGD-).
Derek M. Doroski (5680664), Holly N. Baca (5680649), Colleen M. Rylatt (5680652), Karina E. Diaz (5680661), Jace J. VanSteenburg (5680658), Jessica C. Belkowski (5680634), Daniel A. Schmitt (5680637), Elizabeth M. Hernandez (5680640), Isaac S. Steffes (5680655), Rosita R. Asawa (5680631), Ann E. Babcock (5680643), Christina K. Lochner (5680646)   +11 more
core   +1 more source

The relationship between cellular adhesion and surface roughness in polystyrene modified by microwave plasma radiation

International Journal of Nanomedicine, 2011
Esmaeil Biazar1, Majid Heidari2, Azadeh Asefnezhad2, Naser Montazeri11Department of Chemistry, Islamic Azad University, Tonekabon Branch, Mazandaran; 2Department of Biomaterial Engineering, Faculty of Biomedical Engineering, Science and Research Branch ...
Biazar E, Heidari M, Asfnezhad A, Montazeri N   +3 more
doaj  

Podosomes as smart regulators of cellular adhesion

European Journal of Cell Biology, 2006
Podosomes are punctate adhesion structures first described in osteoclasts and next found in src-transformed cells of mesenchymal origin. Podosomes were never observed in cultured epithelial cells where cell-matrix adhesion structures were represented only by focal contacts and hemidesmosomes interacting with microfilaments and intermediate filaments ...
Laura, Spinardi, Pier Carlo, Marchisio
openaire   +2 more sources

Flow Enabled Target Capture Halbach‐based magnetic enrichment increases circulating tumor cell capture from blood in metastatic cancer patients

Molecular Oncology, EarlyView.
Pair‐wise comparison of the CellSearch and FETCH enrichment technologies for circulating tumor cells (CTCs) from metastatic breast, prostate, and small cell lung cancer patients shows an increased capture of CTCs using FETCH enrichment. The clinical implementation of circulating tumor cells (CTCs) as a predictive tool for therapy efficacy in the ...
Michiel Stevens, Anouk Mentink, Tom Niessink, Frank Coumans, Leonie Mekenkamp, Ruchi Bansal, Jeroen Hiltermann   +6 more
wiley   +1 more source

Oncogenic DMTF1β promotes cancer cell motility by regulating autophagy through ULK1 stabilization

Molecular Oncology, EarlyView.
In the current study, we demonstrate that the oncogene DMTF1β regulates ULK1 stability by reducing its proteasomal degradation in cancer cells. This stabilization enables ULK1 to induce autophagy, which in turn facilitates cancer cell migration. Consequently, reduced DMTF1β levels lead to decreased autophagy and impaired cancer cell migration.
Jun Xu, Nicolas J. Niklaus, Anna M. Schläfli, Igor Tokarchuk, Magali Humbert, Federico La Manna, Bich Vu, David Maul, Ramin Radpour, Marianna Kruithof‐de Julio, Inti Zlobec, Jörn Dengjel, Bruce E. Torbett, Mario P. Tschan   +13 more
wiley   +1 more source

Priming stem cells with protein kinase C activator enhances early stem cell-chondrocyte interaction by increasing adhesion molecules

Biological Research, 2018
Background Osteoarthritis (OA) can be defined as degradation of articular cartilage of the joint, and is the most common degenerative disease. To regenerate the damaged cartilage, different experimental approaches including stem cell therapy have been ...
Dong-Sik Chae, Chang Youn Lee, Jiyun Lee, Hyang-Hee Seo, Chong-Hyuk Choi, Seahyoung Lee, Ki-Chul Hwang   +6 more
doaj   +1 more source