Results 171 to 180 of about 2,209,887 (300)

Dose‐dependent hepatotoxicity of hydrogen peroxide in HepG2 cells and its modulation by CYP450 induction

FEBS Open Bio, EarlyView.
NMR metabolomics revealed concentration‐dependent metabolic perturbations in HepG2 cells exposed to H2O2. Rifampicin pretreatment enhanced metabolic competence, attenuated toxin‐induced alterations and produced metabolite profiles more consistent with human liver physiology, supporting the use of CYP450‐induced HepG2 models for improved in vitro ...
Maren Jinks, Garth L. Maker, Emily C. Davies, Berin A. Boughton, Samantha Lodge   +4 more
wiley   +1 more source

Cellular adhesion-dependent 3D morphogenesis indicating brain tumor aggressiveness and chemosensitivity in spherical cavity culture. [PDF]

Exp Hematol Oncol
Huynh T, Kim J, Amartumur S, Choi I, Lee JY, Lee LP, Heo C.   +6 more
europepmc   +1 more source

KDAC6 alters cell morphology and motility through positive and negative modulation of F‐actin distribution

FEBS Open Bio, EarlyView.
KDAC6 has been associated with cell motility and actin structures, but specific domain contributions are not established. The two catalytic domains have differential effects on motility and F‐actin regulation, affecting cortical F‐actin density, motility, stress fibers, and cell spreading.
Taylor V. Joseph, Andrea B. Pham, Kiara E. Bornes, Razan H. Hammad, Chelsea A. Rousseve‐Ross, Thomas M. Huckaba, Terry J. Watt, Tasha B. Toro   +7 more
wiley   +1 more source

Organization and Dynamics of Focal Adhesions: Light Diffraction Analysis of Cellular Adhesion on Nanopatterned Surfaces. [PDF]

ACS Appl Mater Interfaces
Szekacs I, Novák S, Kovacs B, Dicső Z, Péter B, Bonyár A, Popov R, Frutiger A, Horvath R.   +8 more
europepmc   +1 more source

Comparative proteomics analysis indicates that palmatine contributes to transepithelial migration by regulating cellular adhesion. [PDF]

Pharm Biol, 2020
Hui W, Feng Y, Ruihua X, Jiongjie H, Dongan C, Yan S, Shidong Z.   +6 more
europepmc   +1 more source

Identifying and characterising a plant GH1 β‐glucosidase that exhibits hydrolytic activity on N‐linked glucopyranoside

FEBS Open Bio, EarlyView.
We report the first β‐glucosidase with demonstrated hydrolytic activity on an N‐linked glycopyranoside. The enzyme, native to maize, was biochemically characterised for this novel reaction, and structural modelling of the enzyme–substrate complex revealed several clues to the underlying reduced catalytic rate relative to its native O‐glycopyranoside ...
Hani Gharabli, Carlotta Chiesa, Maher Abou Hachem, Ditte Hededam Welner   +3 more
wiley   +1 more source

Keratin Additive for Cellular Adhesion in Transcutaneous Prosthetics. [PDF]

J Tissue Eng Regen Med
Cagle AL, Szulc EL, Flaggert J, Arias Y, Nikhar A, Tadio D, Durant JA, Gitajn IL, Hixon KR.   +8 more
europepmc   +1 more source

Zeaxanthin-Rich Extract from Superfood Lycium barbarum Selectively Modulates the Cellular Adhesion and MAPK Signaling in Melanoma versus Normal Skin Cells In Vitro. [PDF]

Molecules, 2021
Cenariu D, Fischer-Fodor E, Țigu AB, Bunea A, Virág P, Perde-Schrepler M, Toma VA, Mocan A, Berindan-Neagoe I, Pintea A, Crișan G, Cenariu M, Maniu A.   +12 more
europepmc   +1 more source

Structural studies and functional engineering of NanX: an anhydro‐sialic acid transporter from Escherichia coli

FEBS Open Bio, EarlyView.
Biophysical characterisation shows that NanX, a membrane transport protein from the major facilitator superfamily (MFS), forms both monomers and dimers after purification. AlphaFold modelling and substrate docking provide information on residues likely involved in substrate recognition for NanX and another MFS member, NanT.
Michael C. Newton‐Vesty, Kelsi R. Hall, Zachary D. Tillett, Liam S. Turk, James S. Davies, Michael J. Currie, Hamish G. Brown, Sepideh Valimehr, Peter D. Mace, Andrew E. Whitten, Santosh Panjikar, Eric Hanssen, Rachel A. North, Renwick C.J. Dobson   +13 more
wiley   +1 more source

5-氨基酮戊酸光動力效應誘發細胞骨架重組及其與粒線體功能異常之關聯性

, 2008
Background and Objective: This study investigated the early cellular events which occurred after mitochondrial photodamage induced by 5- aminolevulinic acid-mediated photodynamic therapy (ALA-PDT).
蔡瑞章;吳佳倫;簡雄飛;陳進庭, TSAI, JUI-CHANG;WU, CHIA-LUN;CHIEN, HSIUNG-FEI;CHEN, CHIN-TIN   +1 more
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