Results 191 to 200 of about 2,209,887 (300)

Cell surface CD11c as a neutrophil aging marker molecule

FEBS Open Bio, EarlyView.
Cell surface CD11chi neutrophils were more aged and had better phagocytic function than CD11c−/lo neutrophils. Transcriptomic analysis of CD11chi neutrophils and CD11c−/lo neutrophils in pediatric population showed that the most difference was seen in infants.
Sophia Koutsogiannaki, Fahd Alhamdan, Erik Malm, Marie Bermudez, Samuel Y. Kim, Koichi Yuki   +5 more
wiley   +1 more source

Differential Effect of Ticagrelor Versus Clopidogrel by Causative Classification of Stroke Classification and Vascular Cellular Adhesion Molecule-1 Level on the Risk of Recurrent Stroke: A Post Hoc Analysis of the CHANCE-2 Trial. [PDF]

J Am Heart Assoc
Li H, Xia X, Xu Q, Meng X, Wang Y, Wang A.   +5 more
europepmc   +1 more source

In silico design and validation of high-affinity RNA aptamers targeting epithelial cellular adhesion molecule dimers. [PDF]

Proc Natl Acad Sci U S A, 2020
Bell DR, Weber JK, Yin W, Huynh T, Duan W, Zhou R.   +5 more
europepmc   +1 more source

The C‐terminal domain of yeast Arginyltransferase1 is essential for its catalytic activity

FEBS Open Bio, EarlyView.
Arginyltransferase 1 (Ate1), a eukaryotic enzyme, catalyses arginylation, transferring arginine from tRNA‐Arg to the amino terminus of the target protein. Overexpression of Ate1 in yeast is lethal and is dependent on arginylation. This study elucidates how mutations in the cofactor‐binding and active site of Ate1 and truncation of its structural ...
Vikas Kumar Yadav, Shweta Shweta, Manisha Malhotra, Vikash Maurya, Akhilesh Kumar   +4 more
wiley   +1 more source

STAT3 expression is reduced in cardiac pericytes in HFpEF and its loss reduces cellular adhesion and induces pericyte senescence. [PDF]

FEBS Lett
Vanicek LR, Fischer A, Ruz Jurado M, Tamiato A, Procida-Kowalski T, Wilhelm J, Hecker D, Merten M, Escher F, Kattih B, Puntmann V, John D, Schulz MH, Nagel E, Dimmeler S, Luxán G.   +15 more
europepmc   +1 more source

IGF2 knockout reduces but does not abolish osteosarcoma growth in vitro and in vivo

FEBS Open Bio, EarlyView.
To test whether endogenous IGF2 promotes osteosarcoma growth, IGF2 was knocked out in Saos2 cells via CRISPR‐Cas9. KO cells showed reduced proliferation in vitro, and knockout xenografts in mice reached only ~25% of wild‐type tumor volume. Insulin‐like growth factor 2 (IGF2) is implicated in osteosarcoma, but direct functional evidence of its role is ...
Shun Yao, Marco Archetti
wiley   +1 more source

Functionalization of Polyethylene Terephthalate (PETE) Membranes for the Enhancement of Cellular Adhesion in Organ-on-a-Chip Devices. [PDF]

ACS Appl Mater Interfaces
Sobejano de la Merced C, Doveri L, Muñoz Santoro T, García J, Garmendia J, Cortés Domínguez I, Díaz Fernández YA, Ortiz de Solórzano C.   +7 more
europepmc   +1 more source

Fluorination: A strategy to tune the interactions of molecules and nanoscale systems with biological matter

FEBS Open Bio, EarlyView.
This minireview explores fluorination as a key strategy to optimize therapeutic molecules and nanocarriers. By incorporating different fluorinated motifs—from single atoms to linear and branched chains—drug delivery, cellular uptake, and colloidal stability can be improved and fine‐tuned.
Martina Beccalli, Beatrice Lucia Bona, Francesca Baldelli Bombelli   +2 more
wiley   +1 more source

Absence of immunoreaction and cellular adhesion in a polyvinylpyrrolidone-coated ventricular catheter with choroid plexus obstruction: A case report. [PDF]

Surg Neurol Int
Romero B, Jison G, Self S, Lee S, Sato S, Tran CT, Castaneyra-Ruiz L, Muhonen M.   +7 more
europepmc   +1 more source

Correction for Bell et al., In silico design and validation of high-affinity RNA aptamers targeting epithelial cellular adhesion molecule dimers. [PDF]

Proc Natl Acad Sci U S A, 2021
europepmc   +1 more source