Results 21 to 30 of about 121,160 (299)
Mitochondrial Impairment: A Common Motif in Neuropsychiatric Presentation? The Link to the Tryptophan–Kynurenine Metabolic System [PDF]
, 2022 Nearly half a century has passed since the discovery of cytoplasmic inheritance of human chloramphenicol resistance. The inheritance was then revealed to take place maternally by mitochondrial DNA (mtDNA).
Szabó, Ágnes +11 more
core +1 more source
The Multiple Functions of Rho GTPases in Fission Yeasts [PDF]
, 2021 The Rho family of GTPases represents highly conserved molecular switches involved in a plethora of physiological processes. Fission yeast Schizosaccharomyces pombe has become a fundamental model organism to study the functions of Rho GTPases over the ...
Jero Vicente-Soler +4 more
core +1 more source
FRET sensors reveal the retinal entry pathway in the G protein-coupled receptor rhodopsin
iScience, 2022 Summary: The photoreceptor rhodopsin (Rho) becomes active when a tethered inverse agonist ligand (11CR) is photoconverted to an agonist (ATR). The ligand-binding pocket of inactive rhodopsin is completely enclosed, whereas active rhodopsin displays pores
He Tian +4 more
doaj +1 more source
Biophysical Tools to Study Cellular Mechanotransduction [PDF]
Bioengineering, 2017 The cell membrane is the interface that volumetrically isolates cellular components from the cell’s environment. Proteins embedded within and on the membrane have varied biological functions: reception of external biochemical signals, as membrane channels, amplification and regulation of chemical signals through secondary messenger molecules ...
Muhamed, Ismaeel +2 more
openaire +4 more sources
Scientific Reports, 2021 In recent years’ synthesis of metal nanoparticle using plants has been extensively studied and recognized as a non-toxic and efficient method applicable in biomedical field.
Enerelt Urnukhsaikhan +4 more
doaj +1 more source
Metabolomic profiling of ZrO2 nanoparticles in MC3T3‐E1 cells
IET Nanobiotechnology, 2021 The authors' previous study showed that zirconium oxide nanoparticles (ZrO2 NPs) induce toxic effects in MC3T3‐E1 cells; however, its toxicological mechanism is still unclear.
Mingfu Ye +3 more
doaj +1 more source
Cell Reports, 2016 Release site clearance is an important process during synaptic vesicle (SV) recycling. However, little is known about its molecular mechanism. Here we identify self-assembly of exocytosed Synaptobrevin 2 (Syb2) and Synaptophysin 1 (Syp1) by homo- and ...
Rajit Rajappa +4 more
doaj +1 more source
iScience, 2022 Summary: Cholesterol is a major regulator of multiple types of ion channels. Although there is increasing information about cholesterol binding sites, the molecular mechanisms through which cholesterol binding alters channel function are virtually ...
Nicolas Barbera +8 more
doaj +1 more source
MMP-9 Signaling Pathways That Engage Rho GTPases in Brain Plasticity [PDF]
, 2021 The extracellular matrix (ECM) has been identified as a critical factor affecting synaptic function. It forms a functional scaffold that provides both the structural support and the reservoir of signaling molecules necessary for communication between ...
Paulina Rybak +6 more
core +1 more source
In vitro assembly, positioning and contraction of a division ring in minimal cells
Nature Communications, 2022 Constructing a minimal protein machinery for self-division of membrane compartments is a major goal of bottom-up synthetic biology. Here, authors achieved the assembly, placement and onset of contraction of a minimal division ring in lipid vesicles.
Shunshi Kohyama +2 more
doaj +1 more source