Modulation of Lysosomal Cl− Mediates Migration and Apoptosis through the TRPML1 as a Lysosomal Cl− Sensor [PDF]
Lysosomes are responsible for protein degradation and clearance in cellular recycling centers. It has been known that the lysosomal chloride level is enriched and involved in the intrinsic lysosomal function.
Jeong Hee Hong, Dongun Lee
core +1 more source
Temperature-sensitive migration dynamics in neutrophil-differentiated HL-60 cells
Cell migration plays an essential role in wound healing and inflammatory processes inside the human body. Peripheral blood neutrophils, a type of polymorphonuclear leukocyte (PMN), are the first cells to be activated during inflammation and subsequently ...
Galina Khachaturyan +9 more
doaj +1 more source
Applications of Multiparametric Imaging Atomic Force Microscopy in Probing Cellular and Molecular Mechanics [PDF]
The advent of atomic force microscopy (AFM) provides a powerful tool for probing the physical properties of native biological samples with unprecedented spatiotemporal resolution at the micro/nanoscale, significantly complementing traditional biochemical
Li Mi +3 more
core +1 more source
Rho GTPases as Key Molecular Players within Intestinal Mucosa and GI Diseases [PDF]
Rho proteins operate as key regulators of the cytoskeleton, cell morphology and trafficking. Acting as molecular switches, the function of Rho GTPases is determined by guanosine triphosphate (GTP)/guanosine diphosphate (GDP) exchange and their lipidation
Luz d. C. Martínez-Sánchez +9 more
core +2 more sources
The Review of Bioeffects of Static Magnetic Fields on the Oral Tissue-Derived Cells and Its Application in Regenerative Medicine [PDF]
Magnets have been widely used in dentistry for orthodontic tooth movement and denture retention. Nevertheless, criticisms have arisen regarding the biosafety of static magnetic field (SMF) effects on surrounding tissues.
Haw-Ming Huang +3 more
core +1 more source
Fundamental Concepts in Biophysics [PDF]
HANDBOOK OF MODERN BIOPHYSICS Series Editor Thomas Jue, PhD Handbook of Modern Biophysics brings current biophysics topics into focus, so that biology, medical, engineering, mathematics, and physical-science students or researchers can learn fundamental ...
Jue, Thomas
core +1 more source
Gold nanoparticles explore cells: cellular uptake and their use as intracellular probes [PDF]
Understanding uptake of nanomaterials by cells and their use for intracellular sensing is important for studying their interaction and toxicology as well as for obtaining new biological insight.
Septiadi, Dedy +7 more
core +1 more source
Single-Molecule Cellular Biophysics [PDF]
Research on single-molecule cellular biophysics is an emerging field that is rapidly advancing based on the development of new instrumentation and experimental designs. To understand complex biological systems, researchers require instrumentation and techniques that span many orders of scale.
openaire +2 more sources
RyR1-related myopathy mutations in ATP and calcium binding sites impair channel regulation
The type 1 ryanodine receptor (RyR1) is an intracellular calcium (Ca2+) release channel on the sarcoplasmic/endoplasmic reticulum that is required for skeletal muscle contraction.
Qi Yuan +9 more
doaj +1 more source
High Throughput strategies Aimed at Closing the GAP in Our Knowledge of Rho GTPase Signaling [PDF]
Since their discovery, Rho GTPases have emerged as key regulators of cytoskeletal dynamics. In humans, there are 20 Rho GTPases and more than 150 regulators that belong to the RhoGEF, RhoGAP, and RhoGDI families.
Mélanie Laurin +2 more
core +1 more source

