Results 11 to 20 of about 1,727 (169)

Antibacterial activity and characteristics of silver nanoparticles biosynthesized from Carduus crispus

open access: yesScientific Reports, 2021
In recent years’ synthesis of metal nanoparticle using plants has been extensively studied and recognized as a non-toxic and efficient method applicable in biomedical field.
Enerelt Urnukhsaikhan   +4 more
doaj   +1 more source

Synaptophysin 1 Clears Synaptobrevin 2 from the Presynaptic Active Zone to Prevent Short-Term Depression

open access: yesCell Reports, 2016
Release site clearance is an important process during synaptic vesicle (SV) recycling. However, little is known about its molecular mechanism. Here we identify self-assembly of exocytosed Synaptobrevin 2 (Syb2) and Synaptophysin 1 (Syp1) by homo- and ...
Rajit Rajappa   +4 more
doaj   +1 more source

Metabolomic profiling of ZrO2 nanoparticles in MC3T3‐E1 cells

open access: yesIET Nanobiotechnology, 2021
The authors' previous study showed that zirconium oxide nanoparticles (ZrO2 NPs) induce toxic effects in MC3T3‐E1 cells; however, its toxicological mechanism is still unclear.
Mingfu Ye   +3 more
doaj   +1 more source

Cholesterol-induced suppression of Kir2 channels is mediated by decoupling at the inter-subunit interfaces

open access: yesiScience, 2022
Summary: Cholesterol is a major regulator of multiple types of ion channels. Although there is increasing information about cholesterol binding sites, the molecular mechanisms through which cholesterol binding alters channel function are virtually ...
Nicolas Barbera   +8 more
doaj   +1 more source

Temperature-sensitive migration dynamics in neutrophil-differentiated HL-60 cells

open access: yesScientific Reports, 2022
Cell migration plays an essential role in wound healing and inflammatory processes inside the human body. Peripheral blood neutrophils, a type of polymorphonuclear leukocyte (PMN), are the first cells to be activated during inflammation and subsequently ...
Galina Khachaturyan   +9 more
doaj   +1 more source

In vitro assembly, positioning and contraction of a division ring in minimal cells

open access: yesNature Communications, 2022
Constructing a minimal protein machinery for self-division of membrane compartments is a major goal of bottom-up synthetic biology. Here, authors achieved the assembly, placement and onset of contraction of a minimal division ring in lipid vesicles.
Shunshi Kohyama   +2 more
doaj   +1 more source

RyR1-related myopathy mutations in ATP and calcium binding sites impair channel regulation

open access: yesActa Neuropathologica Communications, 2021
The type 1 ryanodine receptor (RyR1) is an intracellular calcium (Ca2+) release channel on the sarcoplasmic/endoplasmic reticulum that is required for skeletal muscle contraction.
Qi Yuan   +9 more
doaj   +1 more source

Synthetic cell division via membrane-transforming molecular assemblies

open access: yesBMC Biology, 2019
Reproduction, i.e. the ability to produce new individuals from a parent organism, is a hallmark of living matter. Even the simplest forms of reproduction require cell division: attempts to create a designer cell therefore should include a synthetic cell ...
Simon Kretschmer   +3 more
doaj   +1 more source

Organizing the interface—Plasma membrane architecture and receptor dynamics in virus‐cell interactions

open access: yesFEBS Letters, EarlyView.
Plasma membranes contain dynamic nanoscale domains that organize lipids and receptors. Because viruses operate at similar scales, this architecture shapes early infection steps, including attachment, receptor engagement, and entry. Using influenza A virus and HIV‐1 as examples, we highlight how receptor nanoclusters, multivalent glycan interactions ...
Jan Schlegel, Christian Sieben
wiley   +1 more source

Biophysical approaches for studying viral entry

open access: yesFEBS Letters, EarlyView.
Viruses infect all living organisms and have been responsible for major epidemics and pandemics. Their ongoing evolutionary battle with host defenses creates a constant need for improved tools to study viral behavior. Advancing methods to probe viral attachment, fusion, and genome release deepen our understanding of how infections begin and support the
Inbar Yosibash, Raya Sorkin
wiley   +1 more source

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