Evaluation of Histologically and Histochemically Proven Cases of Vitiligo and its Correlation with CD4+ and CD8+ Lymphocyte Counts using Flow Cytometry [PDF]
Journal of Clinical and Diagnostic Research, 2017 Introduction: Vitiligo is an acquired cutaneous disorder characterized by progressive and selective destruction of melanocytes from the epidermis. Autoimmunity is strongly implicated in its pathogenesis.
Moninder Kaur +3 more
doaj +1 more source
Cellular Automaton Model for Immunology of Tumor Growth [PDF]
arXiv, 1998 The stochastic discrete space-time model of an immune response on tumor spreading in a two-dimensional square lattice has been developed. The immunity-tumor interactions are described at the cellular level and then transferred into the setting of cellular automata (CA).
arxiv
Cellular Innate Immunity: An Old Game with New Players
Journal of Innate Immunity, 2016 Innate immunity is a rapidly evolving field with novel cell types and molecular pathways being discovered and paradigms changing continuously. Innate and adaptive immune responses are traditionally viewed as separate from each other, but emerging ...
G. Gasteiger +5 more
semanticscholar +1 more source
Decoding the dual role of autophagy in cancer through transcriptional and epigenetic regulation
FEBS Letters, EarlyView.Transcriptional and epigenetic regulation controls autophagy, which exerts context‐dependent effects on cancer: Autophagy suppresses tumorigenesis by maintaining cellular homeostasis or promotes tumor progression by supporting survival under stress. In this “In a Nutshell” article, we explore the intricate mechanisms of the dual function of autophagy ...
Young Suk Yu, Ik Soo Kim, Sung Hee Baek
wiley +1 more source
TLR3 Deficiency Leads to a Dysregulation in the Global Gene-Expression Profile in Murine Oviduct Epithelial Cells Infected with Chlamydia muridarum [PDF]
, 2019 OBJECTIVE Describe the implementation and effects of Mobile Acute Care for Elders (MACE) consultation at a Veterans Affairs Medical Center (VAMC). DESIGN Retrospective cohort analysis.
Derbigny, Wilbert A, Kumar, Ramesh
core +1 more source
Molecular Therapy: Methods & Clinical Development, 2020 Pompe disease is a lysosomal storage disorder caused by malfunctions of the acid alpha-glucosidase (GAA) enzyme with a consequent toxic accumulation of glycogen in cells.
Giuseppa Piras +17 more
doaj
Immunology of oral candidiasis
Journal of Pharmacy and Bioallied Sciences, 2014 A successful pathogen is one that is able to effectively survive and evade detection by the host immune defense. Oral candidiasis has adopted strategies, which evade host defense and eventually cause disease in at-risk patients.
Janardhanam Dineshshankar +5 more
doaj +1 more source
SIMMUNE, a tool for simulating and analyzing immune system behavior [PDF]
arXiv, 1999 We present a new approach to the simulation and analysis of immune system behavior. The simulations that can be done with our software package called SIMMUNE are based on immunological data that describe the behavior of immune system agents (cells, molecules) on a microscopial (i.e.
arxiv
Transition between immune and disease states in a cellular automaton model of clonal immune response [PDF]
, 1997 In this paper we extend the Celada-Seiden (CS) model of the humoral immune response to include infectious virus and cytotoxic T lymphocytes (cellular response). The response of the system to virus involves a competition between the ability of the virus to kill the host cells and the host's ability to eliminate the virus.
arxiv +1 more source
Cellular immunity to viral antigens limits E1-deleted adenoviruses for gene therapy.
Proceedings of the National Academy of Sciences of the United States of America, 1994 An important limitation that has emerged in the use of adenoviruses for gene therapy has been loss of recombinant gene expression that occurs concurrent with the development of pathology in the organ expressing the transgene.
Yiping Yang +5 more
semanticscholar +1 more source