Results 191 to 200 of about 2,153,248 (300)

Innate immune responsiveness predicts enhanced cellular immunity and symptomatic disease after controlled human influenza infection. [PDF]

Nat Med
Papargyris L, Xu J, Broderick C, Huang A, Gore T, Reynaldi A, Dayananda P, Collins AM, Ascough S, Wong N, Guy J, Song J, Kar S, Bergstrom E, Slater L, Gardener Z, Paterson S, Marjaneh MM, Nichols SJ, Wright VJ, Park MK, McKendry R, Nicholson B, McClain M, Burke TW, Wagstaffe H, Klein J, Levin M, Grifoni A, Woods CW, Davenport MP, Tsang JS, Chain B, Kaforou M, Chiu C.   +34 more
europepmc   +1 more source

Vascular normalization confers an endothelial immune suppressive gene expression profile

Molecular Oncology, EarlyView.
We compare the immunoregulatory gene expression profiles of healthy endothelial cells or endothelial cells from tumors having a normalized endothelium (low leakage) with that of wild‐type tumors (high leakage) and observe that the wild‐type tumor endothelium exhibits immunostimulatory properties.
Liqun He, Michael Welsh
wiley   +1 more source

Foot-and-mouth disease virus-like particle mRNA vaccine induces strong humoral and cellular immunity. [PDF]

Appl Microbiol Biotechnol
Liu H, Zhang Y, Mu S, Hou F, Jiang L, Wang Z, Dong H, Mehdi MM, Guo H, Sun S.   +9 more
europepmc   +1 more source

RoundMi: A quantitative method to analyze mitochondrial morphology in mitotic cells

FEBS Open Bio, EarlyView.
RoundMi is a workflow for rapid analysis of mitochondrial morphology in mitotic cells. By combining adaptive preprocessing with automated segmentation and quantification, it enables accurate measurements from single focal plane images, reducing acquisition time and computational demands while remaining compatible with high‐throughput fixed and live ...
Elmira Parvindokht Bararpour, Christine Volmert, Valentina Piano   +2 more
wiley   +1 more source

High-dose influenza vaccine augments serological and cellular immunity of older people with HIV. [PDF]

JCI Insight
Kupritz J, Davis S, Liu T, Singh P, Díaz-Pachón DA, Rodriguez A, Boyd SD, Pahwa R, Pallikkuth S, Pahwa SG.   +9 more
europepmc   +1 more source

UiO‐66 metal–organic frameworks in biomedicine: From structural tunability to bioimaging, photodiagnostics, and photodynamic cancer therapy

FEBS Open Bio, EarlyView.
UiO‐66(Zr) metal–organic frameworks are chemically stable, biocompatible, and highly tunable nanomaterials. Their modular structure enables controlled drug delivery, multimodal bioimaging, and light‐activated photodynamic therapy, supporting integrated diagnostic and therapeutic (theranostic) applications in cancer and biomedical research.
Veronika Huntošová, Grigorii Rakhalskii, Miroslav Almáši   +2 more
wiley   +1 more source

Proteome-wide curation of experimentally validated HPV T-cell epitopes identifies key gaps in our understanding of cellular immunity to HPV and informs vaccine design. [PDF]

Front Immunol
Putra SP, Cankat S, Swadling L.
europepmc   +1 more source

Aquaporin‐3 and aquaporin‐5 impact the development of pancreatic ductal adenocarcinoma spheroids

FEBS Open Bio, EarlyView.
Schematic representation of the role of aquaporin‐3 (AQP3) and aquaporin‐5 (AQP5) in pancreatic ductal adenocarcinoma (PDAC). Both proteins are upregulated in PDAC and are associated with tumor progression and metastatic potential. Silencing AQP3 or AQP5 in PDAC spheroids results in decreased diameter, area, and overall growth, underscoring their key ...
Catarina Pimpão, Diogo M. Engrácia, Graça Soveral, Filipa Mendes   +3 more
wiley   +1 more source

Cellular Immunity in Obesity: Pathophysiological Insights and the Impact of Bariatric Surgery. [PDF]

Int J Mol Sci
Rivera-Carranza T, León-Téllez-Girón A, González-Vázquez R, Vázquez-Cárdenas P, Esquivel-Campos AL, Mendoza-Pérez F, Rojano-Rodríguez ME, Mimiaga-Hernández C, Cifuentes-Goches JC, Peralta-Valle OE, Zúñiga-León E, Bojalil-Parra R.   +11 more
europepmc   +1 more source

Small RNA pathways in mammalian oocytes

FEBS Open Bio, EarlyView.
Three distinct small RNA pathways operate in mammalian oocytes: RNAi interference (RNAi), the microRNA (miRNA) pathway, and the PIWI‐associated RNA (piRNA) pathway. These pathways use small RNAs to guide sequence‐specific repression and contribute to oocyte biology by targeting genes and mobile elements or appear insignificant since different ...
Petr Svoboda, Josef Pasulka
wiley   +1 more source