Results 191 to 200 of about 2,055,112 (303)

Proteome-wide curation of experimentally validated HPV T-cell epitopes identifies key gaps in our understanding of cellular immunity to HPV and informs vaccine design. [PDF]

Front Immunol
Putra SP, Cankat S, Swadling L.
europepmc   +1 more source

Accurate and noninvasive prostate cancer detection using plasma‐derived extracellular vesicle RNA

FEBS Open Bio, EarlyView.
Plasma extracellular vesicles were captured with WGA‐conjugated magnetic beads and profiled for RNA biomarkers. A three‐RNA panel (NM_024955, NR_047469, and NR_002564) distinguished prostate cancer from healthy controls and benign prostatic hyperplasia, supporting a simple, noninvasive approach to improve prostate cancer detection.
Hanping Wei, Haoran Wu, Wei Feng
wiley   +1 more source

Enhanced Th1 Cellular Immunity Induced by an RSV-F mRNA Vaccine Rationally Designed Using NLP Algorithms. [PDF]

Vaccines (Basel)
Xia ZW, Tang Q, Pan JJ, Liu J, Jia LX, Zhang GM, Xie MN, Zheng JH, Lv CS, Zhang L, Shi YH, He L, Luo M, Zhao JL.   +13 more
europepmc   +1 more source

Delivery of DNA‐encoded vaccines and proteins in mice using cutaneous suction‐mediated transfection

FEBS Open Bio, EarlyView.
Cutaneous suction‐mediated transfection in mice for delivery of DNA‐encoded vaccines and proteins. A critical limitation of DNA vaccines and other therapeutics is transfection in vivo to produce the encoded antigens or therapeutic proteins. Cutaneous suction‐based methods have demonstrated effectiveness in many animal models and have been successfully ...
Emran O. Lallow, Isabel Brandtjen, Yaxin Mo, Melissa Gulley, Louis Osorio, Sagar Kudchodkar, Nandita C. Jhumur, Christine C. Roberts, Lisa K. Denzin, David I. Shreiber, Biju Parekkadan, Hao Lin, Joel N. Maslow   +12 more
wiley   +1 more source

Reconstitution of cellular immunity after allogenic hematopoietic stem cell transplantation

Tato práce se zabývá problematikou transplantací hematopoetických kmenových buněk a potransplantační rekonstituci buněčné imunity. V práci jsou popsány základní údaje o hematopoetických kmenových buňkách, buněčné imunitě, dárcovství a samotných ...
Jansová, Štěpánka
core  

Cellular Immunity in Obesity: Pathophysiological Insights and the Impact of Bariatric Surgery. [PDF]

Int J Mol Sci
Rivera-Carranza T, León-Téllez-Girón A, González-Vázquez R, Vázquez-Cárdenas P, Esquivel-Campos AL, Mendoza-Pérez F, Rojano-Rodríguez ME, Mimiaga-Hernández C, Cifuentes-Goches JC, Peralta-Valle OE, Zúñiga-León E, Bojalil-Parra R.   +11 more
europepmc   +1 more source

Structural studies and functional engineering of NanX: an anhydro‐sialic acid transporter from Escherichia coli

FEBS Open Bio, EarlyView.
Biophysical characterisation shows that NanX, a membrane transport protein from the major facilitator superfamily (MFS), forms both monomers and dimers after purification. AlphaFold modelling and substrate docking provide information on residues likely involved in substrate recognition for NanX and another MFS member, NanT.
Michael C. Newton‐Vesty, Kelsi R. Hall, Zachary D. Tillett, Liam S. Turk, James S. Davies, Michael J. Currie, Hamish G. Brown, Sepideh Valimehr, Peter D. Mace, Andrew E. Whitten, Santosh Panjikar, Eric Hanssen, Rachel A. North, Renwick C.J. Dobson   +13 more
wiley   +1 more source

The Effects of Past COVID-19 and Vaccination on Antibody Levels, Cellular Immunity, and Cytokine Production by Peripheral Blood Mononuclear Cells. [PDF]

Biomedicines
Desheva YA, Gupalova TV, Kudar PA, Leontieva GF, Kudryavtsev IV, Trulioff AS, Guzenkov DS, Matyushenko VA, Bormotova EA, Sokolovsky DD, Matveev GA, Nikolaev BP, Suvorov AN.   +12 more
europepmc   +1 more source

Avidin is evolutionarily conserved in fish but dispensable for development and resistance against Streptococcus agalactiae in zebrafish

FEBS Open Bio, EarlyView.
The presence of biotin‐binding avidin proteins in fish and their biological significance are poorly characterized. We cataloged fish avidins and demonstrate that they are widely present and evolutionarily conserved. We created avd knockout zebrafish and show that zebavidin is dispensable for development and that resistance of avd knockout embryos in ...
Anni K. Saralahti, Markus J. T. Ojanen, Mataleena Parikka, Otto Kauko, Mika Rämet, Vesa P. Hytönen   +5 more
wiley   +1 more source

T cell antigenic recognition sequencing (TAR-seq) enables precise characterization of vaccine-elicited cellular immunity ex vivo and <i>in vivo</i>. [PDF]

Front Immunol
Chaunzwa M, McElfresh GW, Morrow D, Boggy GJ, Kaza M, Benjamin S, Feltham S, Ojha S, Swarbrick GM, Rott KH, Gilbride RM, Labriola CS, Axthelm MK, Joag V, Kain D, Plessis ND, Walzl G, Lewinsohn DA, Lewinsohn DM, Hansen SG, Picker LJ, Bimber BN.   +21 more
europepmc   +1 more source