Vaccine-induced protection against SARS-CoV-2 requires IFN-γ-driven cellular immune response
Nature Communications, 2023 The overall success of worldwide mass vaccination in limiting the negative effect of the COVID-19 pandemics is inevitable, however, recent SARS-CoV-2 variants of concern, especially Omicron and its sub-lineages, efficiently evade humoral immunity mounted
Xiaolei Wang +15 more
doaj +1 more source
Reprogramming Exosomes as Nanoscale Controllers of Cellular Immunity.
Journal of the American Chemical Society, 2018 Exosomes are naturally occurring membranous vesicles secreted by various types of cells. Given their unique and important biological and pharmacological properties, exosomes have been emerging as a promising form of nanomedicine acting via efficient ...
Qinqin Cheng +5 more
semanticscholar +1 more source
Reviewing the effects of food provisioning on wildlife immunity [PDF]
, 2018 While urban expansion increasingly encroaches on natural habitats, many wildlife species capitalize on anthropogenic food resources, which have the potential to both positively and negatively influence their responses to infection.
Babayan, Simon A. +2 more
core +1 more source
Ubiquitin in Influenza Virus Entry and Innate Immunity [PDF]
, 2016 Viruses are obligatory cellular parasites. Their mission is to enter a host cell, to transfer the viral genome, and to replicate progeny whilst diverting cellular immunity.
Rudnicka, Alina, Yamauchi, Yohei
core +5 more sources
Circumventing antivector immunity: potential use of nonhuman adenoviral vectors [PDF]
, 2014 Adenoviruses are efficient gene delivery vectors based on their ability to transduce a wide variety of cell types and drive high-level transient transgene expression. While there have been advances in modifying human adenoviral (HAdV) vectors to increase
Beard C.W. +30 more
core +3 more sources
Cellular immune reactions in the lung [PDF]
Immunological Reviews, 2012 SummaryThe lung constantly interacts with the environment through thousands of liters of air that are inhaled daily. This continually transports toxic chemicals and particles or pathogenic microorganisms deep into the respiratory system, posing a challenge to physicochemical barriers and the local immune system.
Hasenberg, Mike +2 more
openaire +4 more sources
Understanding how T helper cells learn to coordinate effective immune responses through the lens of reinforcement learning [PDF]
Phys. Rev. Research 3, 013222 (2021), 2019 The adaptive immune system of vertebrates can detect, respond to, and memorize diverse pathogens from past experience. While the clonal selection of T helper (Th) cells is the simple and established mechanism to better recognize new pathogens, the question that still remains unexplored is how the Th cells can acquire better ways to bias the responses ...
arxiv +1 more source
Restriction Factors: From Intrinsic Viral Restriction to Shaping Cellular Immunity Against HIV-1
Frontiers in Immunology, 2018 Antiviral restriction factors are host cellular proteins that constitute a first line of defense blocking viral replication and propagation. In addition to interfering at critical steps of the viral replication cycle, some restriction factors also act as
M. Colomer-Lluch +3 more
semanticscholar +1 more source
Regulating the adaptive immune response to respiratory virus infection [PDF]
, 2012 This article is made available for unrestricted research re-use and secondary analysis in any form or by any means with acknowledgement of the original source.
Braciale, Thomas J. +2 more
core +1 more source
Building Correlation Immune Functions from Sets of Mutually Orthogonal Cellular Automata [PDF]
arXiv, 2022 Correlation immune Boolean functions play an important role in the implementation of efficient masking countermeasures for side-channel attacks in cryptography. In this paper, we investigate a method to construct correlation immune functions through families of mutually orthogonal cellular automata (MOCA).
arxiv