Results 71 to 80 of about 2,153,248 (300)

Design and analysis strategies for robust microbiome ageing research

FEBS Letters, EarlyView.
The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik, İsmail Güderer, Yi Wang, Tayyaba Alvi, Prasoon Pandey, Handan Melike Dönertaş   +5 more
wiley   +1 more source

Diabetes mellitus and cellular immunity [PDF]

, 2006
Interaction between diabetes mellitus and cellular immunity is reviewed in several aspects. Importance of cellular immunity in the development of type 1 diabetes mellitus is discussed.
Kėvelaitis, Egidijus, Paknys, Gintaras, Kondrotas, Anatolijus Juozas   +2 more
core  

Related Article from Rehabilitation for Oncogene Addiction: Role of Immunity in Cellular Sobriety

, 2012
Related Article from Rehabilitation for Oncogene Addiction: Role of Immunity in Cellular ...
Robert H. Vonderheide (14881547), David L. Bajor (14986871)   +1 more
core   +1 more source

Toll-like Receptors and the Control of Immunity

, 2020
The study of innate immunity and its link to inflammation and host defense encompasses diverse areas of biology, ranging from genetics and biophysics to signal transduction and physiology.
Fitzgerald, Katherine A, Kagan, Jonathan C   +1 more
core   +1 more source

FEATURES OF CELLULAR IMMUNITY IN CHILDREN WITH CHRONIC HERPES VIRUS INFECTION DEPENDING ON THE AGE AND DEGREE OF EXPOSURE TO THE DIFFERENT TYPES VIRUSES [PDF]

Annals of Mechnikov's Institute, 2013
The basic parameters of cellular immunity and leukocyte composition of peripheral blood of children suffering HGVI caused by herpes viruses of I-VI types, age groups 3-5, 6-11, 12-14 years, corresponding to different degrees of maturity of immune system,
Volyanskiy A.Yu., Romanova E. A., Igumnova N. I., Sidorenko T. A., Yuchimenko V. I., Konareva K. S.   +5 more
doaj  

ABL kinase‐dependent phosphorylation of SH proteins promotes their direct interaction with CRK family SH2 domains

FEBS Letters, EarlyView.
CT10 regulator of kinase (CRK) and CRK‐Like (CRKL) are signaling adaptors driving cell adhesion, motility, differentiation, and proliferation. SH2‐domain containing (SH) proteins are enriched in YXXP motifs which when phosphorylated create preferred binding sites for CRK family SH2 domains.
Phoebe M. Cousens, Brendan W. Chandler, Anna M. Schmoker, Jaye L. Weinert, Charlotte A. Kearns, Warren T. Yacawych, Amila Šemić, Alicia M. Ebert, Bryan A. Ballif   +8 more
wiley   +1 more source

Malaria impairs T cell clustering and immune priming despite normal signal 1 from dendritic cells [PDF]

, 2007
Interactions between antigen-presenting dendritic cells (DCs) and T cells are essential for the induction of an immune response. However, during malaria infection, DC function is compromised and immune responses against parasite and heterologous antigens
Owain R Millington, Bernd H. Zinselmeyer, Zinselmeyer Bernd H, Brewer James M, Paul Garside, Rush, Catherine M., Rush, C.M., Owain R. Millington, Millington, O.R., Vivienne B Gibson, Catherine M. Rush, Bernd H Zinselmeyer, Rush, C., R. Stephen Phillips, Vivienne B. Gibson, Phillips, R.S., R Stephen Phillips, Catherine M Rush, Zinselmeyer, B.H., Millington, Owain R., Brewer, James M., Gibson Vivienne B, Millington Owain R, Brewer, J.M., Gibson, Vivienne B., Phillips R. Stephen, Garside Paul, Rush Catherine M, Phillips, R. Stephen, Zinselmeyer, Bernd H., Garside, P., James M. Brewer, Garside, Paul, James M Brewer   +33 more
core   +1 more source

Cellular immunity of naïve and BCG vaccinated neonates [PDF]

, 2010
Includes abstract.Includes bibliographical references (leaves 153-187).Despite more than 95% vaccination coverage with Mycobacterium bovis Bacille Calmette-Guérin (BCG), tuberculosis (TB) remains epidemic in South Africa.
Watkins, Marcia Linda Vivienne
core   +1 more source

Immunology of oral candidiasis

Journal of Pharmacy and Bioallied Sciences, 2014
A successful pathogen is one that is able to effectively survive and evade detection by the host immune defense. Oral candidiasis has adopted strategies, which evade host defense and eventually cause disease in at-risk patients.
Janardhanam Dineshshankar, Muniapillai Sivakumar, M Karthikeyan, P Udayakumar, K T Shanmugam, G Kesavan   +5 more
doaj   +1 more source

Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential

FEBS Letters, EarlyView.
Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta, Hari Baskar Balasubramanian, Amir Pasokh, Marietta Zille   +3 more
wiley   +1 more source