Results 81 to 90 of about 3,445,878 (379)

Hemispheric lateralisation and immune function: A systematic review of human research [PDF]

open access: yes, 2011
This is the post-print version of the final paper published in Journal of Neuroimmunology. The published article is available from the link below. Changes resulting from the publishing process, such as peer review, editing, corrections, structural ...
Gidron, Y   +4 more
core   +2 more sources

Insights into PI3K/AKT signaling in B cell development and chronic lymphocytic leukemia

open access: yesFEBS Letters, EarlyView.
This Review explores how the phosphoinositide 3‐kinase and protein kinase B pathway shapes B cell development and drives chronic lymphocytic leukemia, a common blood cancer. It examines how signaling levels affect disease progression, addresses treatment challenges, and introduces novel experimental strategies to improve therapies and patient outcomes.
Maike Buchner
wiley   +1 more source

Attack and defence in cellular decision-making: lessons from machine learning [PDF]

open access: yesPhys. Rev. X 9, 031012 (2019), 2018
Machine learning algorithms can be fooled by small well-designed adversarial perturbations. This is reminiscent of cellular decision-making where ligands (called antagonists) prevent correct signalling, like in early immune recognition. We draw a formal analogy between neural networks used in machine learning and models of cellular decision-making ...
arxiv   +1 more source

Taurine promotes glucagon‐like peptide‐1 secretion in enteroendocrine L cells

open access: yesFEBS Letters, EarlyView.
Taurine, a sulfur‐containing amino acid, is likely taken up by enteroendocrine L cells via the taurine transporter. This process increases the levels of cytosolic ATP. The increase in intracellular Ca2+ concentrations and glucagon‐like peptide‐1 secretion through membrane depolarization is caused by the closure of ATP‐sensitive potassium channels ...
Yuri Osuga   +6 more
wiley   +1 more source

A disease‐associated missense mutation in CYP4F3 affects the metabolism of leukotriene B4 via disruption of electron transfer

open access: yesJournal of Cachexia, Sarcopenia and Muscle, 2022
Background Cytochrome P450 4F3 (CYP4F3) is an ω‐hydroxylase that oxidizes leukotriene B4 (LTB4), prostaglandins, and fatty acid epoxides. LTB4 is synthesized by leukocytes and acts as a chemoattractant for neutrophils, making it an essential component of
Elien Smeets   +18 more
doaj   +1 more source

A Guideline for the Statistical Analysis of Compositional Data in Immunology [PDF]

open access: yesarXiv, 2022
The study of immune cellular composition has been of great scientific interest in immunology because of the generation of multiple large-scale data. From the statistical point of view, such immune cellular data should be treated as compositional. In compositional data, each element is positive, and all the elements sum to a constant, which can be set ...
arxiv  

Error-prone cellular automata as metaphors of immunity as computation [PDF]

open access: yesComplex Systems 24 (2015), 93-111, 2014
Modeling the immune system so that its essential functionalities stand out without the need for every molecular or cellular interaction to be taken into account has been challenging for many decades. Two competing approaches have been the clonal selection theory and the idiotypic-network theory, each stemming from a relatively separate set of ...
arxiv   +1 more source

Vaccination with Klebsiella pneumoniae-derived extracellular vesicles protects against bacteria-induced lethality via both humoral and cellular immunity

open access: yesExperimental and Molecular Medicine, 2015
The emergence of multidrug-resistant Klebsiella pneumoniae highlights the need to develop preventive measures to ameliorate Klebsiella infections. Bacteria-derived extracellular vesicles (EVs) are spherical nanometer-sized proteolipids enriched with ...
W. Lee   +5 more
semanticscholar   +1 more source

Pengaruh Asap Rokok Kretek Terhadap Imunitas Seluler Tikus Betina Strain Lmr [PDF]

open access: yes, 2006
Experimental research was done to understand the effect of cigarette smoke to cellular immunity. In this research, 3 groups of rats were exposed by cigarette smoke for 7, 14, and 21 estrous cycles.
Hartamto, H. (Hadi), Idris, R. (Rosila)
core  

Unraveling Mycobacterium tuberculosis acid resistance and pH homeostasis mechanisms

open access: yesFEBS Letters, EarlyView.
Mycobacterium tuberculosis exhibits a remarkable resilience to acid stress. In this Review, we discuss some of the molecular mechanisms and metabolic pathways used by the tubercle bacilli to adapt and resist host‐mediated acid stress. Mycobacterium tuberculosis (Mtb) is a successful pathogen that has developed a variety of strategies to survive and ...
Janïs Laudouze   +3 more
wiley   +1 more source

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