Results 71 to 80 of about 1,492,586 (335)

Systematic CRISPR-Cas9-Mediated Modifications of Plasmodium yoelii ApiAP2 Genes Reveal Functional Insights into Parasite Development

open access: yesmBio, 2017
Malaria parasites have a complex life cycle with multiple developmental stages in mosquito and vertebrate hosts, and different developmental stages express unique sets of genes.
Cui Zhang   +10 more
doaj   +1 more source

A Cre‐dependent lentiviral vector for neuron subtype‐specific expression of large proteins

open access: yesFEBS Letters, EarlyView.
We designed a versatile and modular lentivector comprising a Cre‐dependent switch and self‐cleaving 2A peptide and tested it for co‐expression of GFP and a 2.8 kb gene of interest (GOI) in mouse cortical parvalbumin (PV+) interneurons and midbrain dopamine (TH+) neurons.
Weixuan Xue   +6 more
wiley   +1 more source

Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?

open access: yesFEBS Letters, EarlyView.
This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes   +3 more
wiley   +1 more source

Energy Efficiency of Network Cooperation for Cellular Uplink Transmissions

open access: yes, 2013
There is a growing interest in energy efficient or so-called "green" wireless communication to reduce the energy consumption in cellular networks. Since today's wireless terminals are typically equipped with multiple network access interfaces such as ...
Zheng, Baoyu, Zhu, Jia, Zou, Yulong
core   +1 more source

Structural insights into lacto‐N‐biose I recognition by a family 32 carbohydrate‐binding module from Bifidobacterium bifidum

open access: yesFEBS Letters, EarlyView.
Bifidobacterium bifidum establishes symbiosis with infants by metabolizing lacto‐N‐biose I (LNB) from human milk oligosaccharides (HMOs). The extracellular multidomain enzyme LnbB drives this process, releasing LNB via its catalytic glycoside hydrolase family 20 (GH20) lacto‐N‐biosidase domain.
Xinzhe Zhang   +5 more
wiley   +1 more source

A Centralized SDN Architecture for the 5G Cellular Network

open access: yes, 2018
In order to meet the increasing demands of high data rate and low latency cellular broadband applications, plans are underway to roll out the Fifth Generation (5G) cellular wireless system by the year 2020. This paper proposes a novel method for adapting
Jha, Pranav   +2 more
core   +1 more source

The role and implications of mammalian cellular circadian entrainment

open access: yesFEBS Letters, EarlyView.
At their most fundamental level, mammalian circadian rhythms occur inside every individual cell. To tell the correct time, cells must align (or ‘entrain’) their circadian rhythm to the external environment. In this review, we highlight how cells entrain to the major circadian cues of light, feeding and temperature, and the implications this has for our
Priya Crosby
wiley   +1 more source

Traffic Prediction of Wireless Cellular Networks Based on Deep Transfer Learning and Cross-Domain Data

open access: yesIEEE Access, 2020
Wireless cellular traffic prediction is a critical issue for researchers and practitioners in the 5G/B5G field. However, it is very challenging since the wireless cellular traffic usually show high nonlinearities and complex patterns.
Qingtian Zeng   +5 more
doaj   +1 more source

Molecular bases of circadian magnesium rhythms across eukaryotes

open access: yesFEBS Letters, EarlyView.
Circadian rhythms in intracellular [Mg2+] exist across eukaryotic kingdoms. Central roles for Mg2+ in metabolism suggest that Mg2+ rhythms could regulate daily cellular energy and metabolism. In this Perspective paper, we propose that ancestral prokaryotic transport proteins could be responsible for mediating Mg2+ rhythms and posit a feedback model ...
Helen K. Feord, Gerben van Ooijen
wiley   +1 more source

Coexistence and Performance Limits for the Cognitive Broadband Satellite System and mmWave Cellular Network

open access: yesIEEE Access, 2020
The application of millimeter wave (mmWave) spectrum for the next generation broadband communications has received significant attention recently. In this work, we investigate the performance limits for the coexistence of the geo-stationary orbit (GEO ...
Qianfeng Zhang   +3 more
doaj   +1 more source

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