Results 151 to 160 of about 2,084,390 (260)

Translating whole‐genome doubling into precision medicine in cancer

Molecular Oncology, EarlyView.
Whole‐genome doubling creates a WGD‐positive tumor state characterized by persistent chromosomal instability, karyotypic diversification, and cellular stress. These same biological pressures drive aggressive tumor evolution while exposing therapeutic vulnerabilities, providing a rationale for WGD‐informed precision medicine. Whole‐genome doubling (WGD)
Sejung Lee, Junghyeok Lim, Jinhyuk Bhin
wiley   +1 more source

Targeting transcription factors associated with hemoglobinopathies: Lessons from successful interventions and implications for cancer

Molecular Oncology, EarlyView.
This review summarizes the transcription factors, repressive chromatin‐modifying complexes, and epigenetic mechanisms that control fetal hemoglobin repression. Notably, many regulators of γ‐globin silencing also function in transcriptional and epigenetic networks that drive cancer, highlighting opportunities to translate advances in hemoglobinopathy ...
Meigen Yu, Puspa Das, Xing Zhang, Xiaodong Cheng   +3 more
wiley   +1 more source

PANoptosis in the pathogenesis of myelodysplastic syndromes

Molecular Oncology, EarlyView.
PANoptosis, a combination of three types of programmed cell death, is mediated by a large protein complex called a PANoptosome. In healthy bone marrow hematopoietic cells, PANoptosis is restricted by inhibitory signaling. In MDS, bone marrow cells become sensitive to the PANoptotic stimuli due to the aberrant inactivation of inhibitory signaling or ...
Rohit Thalla, Jyoti Lamichhane, Cameron Lewis, Peter Breslin, Jiwang Zhang   +4 more
wiley   +1 more source

Comparative biochemistry and physiology.

Gesplitst in ... en: Comparative biochemistry and physiology. A. Comparative physiology [ISSN 0300-9629]Gesplitst in ... en: Comparative biochemistry and physiology. B. Comparative biochemistry [ISSN 0305-0491]Gesplitst in ...
American Society of Zoologists.Division of Comparative Physiology.
core  

Physiology in Central and South America and hope for better times

Cellular and Molecular Physiology Laboratory (CMPL) Department of Obstetrics Division of Obstetrics and Gynaecology School of Medicine Faculty of Medicine Pontificia Universidad Católica de ChileDepartment of Physiology Faculty of Pharmacy Universidad de
Sobrevia, Luis [UNESP]
core   +1 more source

Welcome to the Relaunched Journal of Cellular Physiology. [PDF]

J Cell Physiol
Trevorrow P, Heath RJW.
europepmc   +1 more source

Roles and Functions of ROS and RNS in Cellular Physiology and Pathology. [PDF]

Cells, 2020
Zarkovic N.
europepmc   +1 more source

Spatial biology in cancer epigenetics

Molecular Oncology, EarlyView.
Spatial epigenomics combines molecular profiling with tissue architecture to reveal how gene regulation is organized within intact tissues. In cancer, these technologies uncover the mechanisms driving tumor heterogeneity and microenvironmental interactions, opening new opportunities for biomarker discovery and precision medicine.
Eva Crespo‐García, Manel Esteller
wiley   +1 more source

Light-dependent processes in algae across scales: from cellular physiology to ecological organization. [PDF]

Plant Physiol
Hallmann A.
europepmc   +1 more source

Regulator of G protein signaling 10: Structure, expression and functions in cellular physiology and diseases. [PDF]

Cell Signal, 2020
Almutairi F, Lee JK, Rada B.
europepmc   +1 more source