How structural disorder and polyelectrolyte properties of prothymosin α enable its large interactome
FEBS Letters, EarlyView.In this review, complexes of the fully disordered and highly negatively charged prothymosin α are collected, described, and discussed. Linked to its poly‐electrostatic character, prothymosin α engages a large interactome through multiple different binding modes ranging from fully disordered complexes to short linear motif (SLiM)‐driven interactions ...
Ketty C. Tamburrini +3 more
wiley +1 more source
Origins and Function of VL30 lncRNA Packaging in Small Extracellular Vesicles: Implications for Cellular Physiology and Pathology. [PDF]
Biomedicines, 2021 Mantziou S, Markopoulos GS.
europepmc +1 more source
Kinetic analyses of vasculogenesis inform mechanistic studies
, 2017 Vasculogenesis is a complex process by which endothelial stem and progenitor cells undergo de novo vessel formation. Quantitative assessment of vasculogenesis is a central readout of endothelial progenitor cell functionality. However, current assays lack
Dunn, Kenneth W. +7 more
core +1 more source
Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment
Molecular Oncology, EarlyView.This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley +1 more source
Compensatory ion transport buffers daily protein rhythms to regulate osmotic balance and cellular physiology. [PDF]
Nat Commun, 2021 Stangherlin A +23 more
europepmc +1 more source
Therapeutic Potential of eMedica\u27s Electron-Driven Cell Therapy in Treating Cancer: Addressing Fundamental Aspects of Cellular Physiology [PDF]
Cancer remains one of the leading causes of morbidity and mortality globally, prompting continuous exploration of innovative therapeutic modalities. eMedica’s electron-driven cell therapy represents a promising frontier in cancer treatment, harnessing ...
Reddy , Dr. B Sridhar +5 more
core +1 more source
Hijacking emergency granulopoiesis: Neutrophil ontogeny and reprogramming in cancer
Molecular Oncology, EarlyView.Neutrophils are highly plastic innate immune cells; their functions in cancer extend beyond the tumour microenvironment. This Review summarises current understanding of neutrophil maturation and heterogeneity and highlights tumour‐induced granulopoiesis as a systemic programme that expands immature, immunosuppressive neutrophils via tumour‐derived ...
Gabriela Marinescu, Yi Feng
wiley +1 more source
Publisher Correction: Compensatory ion transport buffers daily protein rhythms to regulate osmotic balance and cellular physiology. [PDF]
Nat Commun, 2021 Stangherlin A +23 more
europepmc +1 more source
Molecular Oncology, EarlyView.Circulating microRNAs as biomarkers of cachexia and sex‐specific cancer in senior dogs. In 25 client‐owned dogs, four circulating miRNAs (miR‐15a, miR‐15b, miR‐16, miR‐140) were downregulated in cachexia, with miR‐16 the strongest individual biomarker (AUC = 0.899).
Soon‐Seok Park +6 more
wiley +1 more source
Physiology Question paper-2018
, 2018 Physiology Question ...
Vidyasagar University
core +1 more source