Results 121 to 130 of about 2,084,390 (260)
MFAP5+ synovial fibroblasts drive LOX upregulation to promote osteoarthritis progression
iScienceSummary: Synovial fibroblasts (SFs), the predominant synovial cell population, drive osteoarthritis (OA) pathogenesis. Understanding SF reprogramming in OA progression may reveal potential targets.
Linzhu Wang +17 more
doaj +1 more source
Molecular Interplay at the Membrane and Impact on Cellular Physiology. [PDF]
J Membr Biol, 2021 Pucadyil T, Kulkarni K, Sengupta D.
europepmc +1 more source
FEBS Letters, EarlyView.Encapsulins are protein nanocompartments that play an important role in iron storage. In the Myxococcus xanthus encapsulin system, two cargo proteins called EncB and EncC contribute to iron mineralization. Here, we show that EncB and EncC generate iron‐containing minerals with distinct chemical compositions, suggesting that the composition of stored ...
Harry B. McDowell +2 more
wiley +1 more source
Frontiers in Physiology is a field journal of the "Frontiers in" journal series. Physiology investigates the function of all living systems. Frontiers in Physiology publishes tier 1 and tier 2 article types that cover this diverse subject from the ...
CAROSELLI, ERIK
core +3 more sources
Long non-coding RNAs: novel regulators of cellular physiology and function. [PDF]
Pflugers Arch, 2022 Oo JA, Brandes RP, Leisegang MS.
europepmc +1 more source
‘Guide and Prejudice’— How Argonautes recognize targets across domains of life
FEBS Letters, EarlyView.Argonaute proteins use short nucleic‐acid guides to locate and regulate specific targets across all domains of life. Despite striking diversity—from human gene silencing to bacterial immune defence—all Argonautes share a conserved three‐stage recognition logic: guide‐directed sampling, progressive target pairing with a conformational checkpoint and ...
Jack P. K. Bravo
wiley +1 more source
Recent Advances in Fluorescence Recovery after Photobleaching for Decoupling Transport and Kinetics of Biomacromolecules in Cellular Physiology. [PDF]
Polymers (Basel), 2022 Cai N +5 more
europepmc +1 more source
The Shewanella oneidensis Fic enzyme SoFic targets the switch‐I region of EF‐Tu for AMPylation
FEBS Letters, EarlyView.Fic enzymes mediate diverse post‐translational modifications across all domains of life, including AMPylation. Prokaryotic EF‐Tu can be AMPylated and deAMPylated by the conserved Fic enzyme SoFic. Structural and biochemical approaches were used to characterize the effect of AMPylation on EF‐Tu, SoFic's enzymatic activities, and the enzyme‐target ...
Svenja Runge +6 more
wiley +1 more source
An expanded whole-cell model of E. coli links cellular physiology with mechanisms of growth rate control. [PDF]
NPJ Syst Biol Appl, 2022 Ahn-Horst TA +4 more
europepmc +1 more source
FEBS Letters, EarlyView.Synechocystis strains deficient in succinate dehydrogenase (SDH) secrete more succinate than the WT under dark anaerobic conditions, supporting that SDH then primarily acts as SDH, not as a fumarate reductase. L‐aspartate oxidase (Laspo) from Synechocystis is functional under anaerobic conditions, reducing fumarate to succinate.
Kateryna Kukil +3 more
wiley +1 more source